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Study Information
Study Attribute Value
CEBS Accession Number: 002-02194-0016-0000-5
Chemical Name: Furfural
CASRN: 98-01-1
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 991433_SCE
Study Result: Negative


Table Instructions and Notes:

Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.


Summary of Sister Chromatid Exchange Data (Trial 1)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 02/12/87 23 Mouse Male B6C3F1 Bone Marrow IP/IJ x 1,  23 hour
  Dose
(mg/kg)		 n SCE / Cell
(Mean ± SEM)		 Pairwise P
Vehicle Control Phosphate Buffered Saline 
 0         
 4 4.02 ± 0.216
Test Chemical Furfural 
50         
 4 4.84 ± 0.477
  
100         
 4 3.44 ± 0.392
  
200         
 4 4.18 ± 0.291
Positive Control Mitomycin-C 
 0.5       
 4 7.11 ± 0.494


Summary of Sister Chromatid Exchange Data (Trial 2)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 08/18/87 42 Mouse Male B6C3F1 Bone Marrow IP/IJ x 1,  42 hour
  Dose
(mg/kg)		 n SCE / Cell
(Mean ± SEM)		 Pairwise P
Vehicle Control Phosphate Buffered Saline 
 0         
 3 5.17 ± 0.932
Test Chemical Furfural 
50         
 4 4.30 ± 0.273
  
100         
 4 3.83 ± 0.343
  
200         
 4 4.05 ± 0.315
Positive Control Mitomycin-C 
 0.5       
 4 4.00 ± 0.145


Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed