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Study Information
Study Attribute Value
CEBS Accession Number: 002-02196-0021-0000-3
Chemical Name: Furfuryl alcohol
CASRN: 98-00-0
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 150910_CA
Study Result: Negative

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 11/24/86 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.9733
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
100         
 8 17.00 ± 4.93 0.0000
Test Chemical Furfuryl alcohol 
75         
 8 2.00 ± 0.53 0.5000
  
150         
 8 4.00 ± 1.93 0.0487
  
300         
 8 0.00 ± 0.00 0.9978
Vehicle Control No Stressor 
 0         
 8 2.00 ± 1.00 0.0000


Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 04/12/88 36 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 36 hour 0.0031
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
100         
 8 27.50 ± 3.25 0.0000
Test Chemical Furfuryl alcohol 
50         
 8 2.00 ± 0.76 0.2749
  
100         
 8 4.00 ± 1.07 0.0166
  
200         
 8 4.50 ± 1.40 0.0075
Vehicle Control No Stressor 
 0         
 7 1.43 ± 0.57 0.0000


Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 01/09/89 36 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 36 hour 0.2665
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
50         
 7 24.86 ± 5.12 0.0000
Test Chemical Furfuryl alcohol 
50         
 8 1.50 ± 0.50 0.5000
  
100         
 8 1.75 ± 0.70 0.3899
  
200         
 8 2.00 ± 1.00 0.2949
Vehicle Control No Stressor 
 0         
 8 1.50 ± 0.82 0.0000


Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 04/02/90 36 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 36 hour 0.6025
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
50         
 8 18.00 ± 1.60 0.0000
Test Chemical Furfuryl alcohol 
50         
 8 1.25 ± 0.53 0.7196
  
100         
 8 0.75 ± 0.37 0.8985
  
200         
 8 1.50 ± 0.98 0.6101
Vehicle Control No Stressor 
 0         
 8 1.75 ± 0.59 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed