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Study Information
Study Attribute Value
CEBS Accession Number: 002-02202-0012-0000-1
Chemical Name: Geranyl acetate
CASRN: 105-87-3
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 125080_SCE
Study Result: Negative


Table Instructions and Notes:

Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.


Summary of Sister Chromatid Exchange Data (Trial 1)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 01/13/87 23 Mouse Male B6C3F1 Bone Marrow IP/IJ x 1,  23 hour
  Dose
(mg/kg)		 n SCE / Cell
(Mean ± SEM)		 Pairwise P
Vehicle Control Corn Oil 
 0         
 4 6.28 ± 0.860
Test Chemical Geranyl acetate 
425         
 3 5.35 ± 0.371
  
850         
 4 5.37 ± 0.965
  
1700         
 4 7.04 ± 0.395
Positive Control Dimethylbenzanthracene 
2.5       
 4 9.29 ± 0.314


Summary of Sister Chromatid Exchange Data (Trial 2)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 01/08/90 42 Mouse Male B6C3F1 Bone Marrow IP/IJ x 1,  42 hour
  Dose
(mg/kg)		 n SCE / Cell
(Mean ± SEM)		 Pairwise P
Vehicle Control Corn Oil 
 0         
 4 4.83 ± 0.879
Test Chemical Geranyl acetate 
425         
 4 6.43 ± 0.996
  
850         
 4 5.10 ± 1.021
  
1700         
 4 4.86 ± 0.293
Positive Control Dimethylbenzanthracene 
2.5       
 4 9.92 ± 1.043


Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed