Genetic Toxicology - Rodent Cytogenetics

Study Information
Study Attribute	Value
CEBS Accession Number:	002-02202-0012-0000-1
Chemical Name:	Geranyl acetate
CASRN:	105-87-3
NTP Study Type:	Genetic Toxicology - Rodent Cytogenetics
NTP Study ID:	125080_SCE
Study Result:	Negative

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Table Instructions and Notes:

Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.

Summary of Sister Chromatid Exchange Data (Trial 1)
Test Type	Start Date	Sample Time (h)	Species	Sex	Strain	Tissue	Protocol	Trend Test P
SCE	01/13/87	23	Mouse	Male	B6C3F1	Bone Marrow	IP/IJ x 1, 23 hour

		Dose (mg/kg)	n	SCE / Cell (Mean ± SEM)
Vehicle Control	Corn Oil	0	4	6.28 ± 0.860
Test Chemical	Geranyl acetate	425	3	5.35 ± 0.371
		850	4	5.37 ± 0.965
		1700	4	7.04 ± 0.395
Positive Control	Dimethylbenzanthracene	2.5	4	9.29 ± 0.314

Summary of Sister Chromatid Exchange Data (Trial 2)
Test Type	Start Date	Sample Time (h)	Species	Sex	Strain	Tissue	Protocol	Trend Test P
SCE	01/08/90	42	Mouse	Male	B6C3F1	Bone Marrow	IP/IJ x 1, 42 hour

		Dose (mg/kg)	n	SCE / Cell (Mean ± SEM)
Vehicle Control	Corn Oil	0	4	4.83 ± 0.879
Test Chemical	Geranyl acetate	425	4	6.43 ± 0.996
		850	4	5.10 ± 1.021
		1700	4	4.86 ± 0.293
Positive Control	Dimethylbenzanthracene	2.5	4	9.92 ± 1.043

Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed