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Study Information
Study Attribute Value
CEBS Accession Number: 002-02202-0013-0000-2
Chemical Name: Geranyl acetate
CASRN: 105-87-3
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 125080_CA
Study Result: Positive

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 08/03/87 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.0066
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
100         
 8 14.50 ± 2.16 0.0000
Test Chemical Geranyl acetate 
425         
 8 4.25 ± 1.03 0.0337
  
850         
 8 1.25 ± 0.53 0.7992
  
1700         
 8 5.75 ± 1.33 0.0030
Vehicle Control No Stressor 
 0         
 8 2.00 ± 0.65 0.0000


Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 07/18/88 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.0027
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
100         
 8 19.50 ± 3.76 0.0000
Test Chemical Geranyl acetate 
1275         
 8 6.00 ± 1.00 0.2675
  
1700         
 8 11.00 ± 2.27 0.0009
Vehicle Control No Stressor 
 0         
 8 5.00 ± 1.65 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed