Study Attribute | Value |
---|---|
CEBS Accession Number: | 002-02202-0014-0000-3 |
Chemical Name: | Geranyl acetate |
CASRN: | 105-87-3 |
NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
NTP Study ID: | A07926_CA |
Study Result: | Negative (Nonstandard Protocol) |
Test Type | Start Date | Sample Time (h) | Species | Sex | Tissue | Protocol | Trend Test P |
---|---|---|---|---|---|---|---|
CA | 05/13/92 | 17 | Mouse | Male | Bone Marrow | Intraperitoneal Injection x 1/study, 17 hour | 0.0000 |
Test Group | Dose (mg/kg) | n | Percent Cells w/ Aberrations (Mean ± SEM) | Pairwise P | |
---|---|---|---|---|---|
Positive Control | Dimethylbenzanthracene | 100 | 0 | 0.00 ± 0.00 | 0.0000 |
200 | 0 | 0.00 ± 0.00 | 0.0000 | ||
Test Chemical | Geranyl acetate | 500 | 0 | 0.00 ± 0.00 | 0.0000 |
1000 | 0 | 0.00 ± 0.00 | 0.0000 | ||
1500 | 0 | 0.00 ± 0.00 | 0.0000 | ||
Vehicle Control | No Stressor | 0 | 0 | 0.00 ± 0.00 | 0.0000 |
Test Type | Start Date | Sample Time (h) | Species | Sex | Tissue | Protocol | Trend Test P |
---|---|---|---|---|---|---|---|
CA | 05/20/92 | 17 | Mouse | Male | Bone Marrow | Intraperitoneal Injection x 1/study, 17 hour | 0.4184 |
Test Group | Dose (mg/kg) | n | Percent Cells w/ Aberrations (Mean ± SEM) | Pairwise P | |
---|---|---|---|---|---|
Positive Control | Dimethylbenzanthracene | 100 | 8 | 4.25 ± 1.33 | 0.0020 |
200 | 8 | 8.50 ± 1.50 | 0.0000 | ||
Test Chemical | Geranyl acetate | 250 | 8 | 1.25 ± 0.53 | 0.3687 |
500 | 8 | 0.75 ± 0.53 | 0.6479 | ||
1000 | 8 | 1.25 ± 0.53 | 0.3687 | ||
Vehicle Control | No Stressor | 0 | 8 | 1.00 ± 0.53 | 0.0000 |
Footnotes: IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed
INHAL: Inhalation
n: Number of animals analyzed