Study Attribute | Value |
---|---|
CEBS Accession Number: | 002-02230-0010-0000-0 |
Chemical Name: | HC blue 2 |
CASRN: | 33229-34-4 |
NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
NTP Study ID: | 908121_SCE |
Study Result: | Positive |
Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.
Test Type | Start Date | Sample Time (h) | Species | Sex | Strain | Tissue | Protocol | Trend Test P |
---|---|---|---|---|---|---|---|---|
SCE | 01/28/86 | 23 | Mouse | Male | B6C3F1 | Bone Marrow | IP/IJ x 1, 23 hour |
Dose (mg/kg) | n | SCE / Cell (Mean ± SEM) | Pairwise P | ||
---|---|---|---|---|---|
Vehicle Control | Dimethyl Sulfoxide | 0 | 4 | 3.98 ± 0.136 | |
Test Chemical | HC blue 2 | 375 | 4 | 6.03 ± 0.254 | |
750 | 4 | 5.46 ± 0.245 | |||
1500 | 4 | 10.00 ± 0.400 | |||
Positive Control | Dimethylbenzanthracene | 2.5 | 4 | 12.15 ± 1.491 |
Test Type | Start Date | Sample Time (h) | Species | Sex | Strain | Tissue | Protocol | Trend Test P |
---|---|---|---|---|---|---|---|---|
SCE | 11/12/86 | 42 | Mouse | Male | B6C3F1 | Bone Marrow | IP/IJ x 1, 42 hour |
Dose (mg/kg) | n | SCE / Cell (Mean ± SEM) | Pairwise P | ||
---|---|---|---|---|---|
Vehicle Control | Dimethyl Sulfoxide | 0 | 4 | 3.76 ± 0.164 | |
Test Chemical | HC blue 2 | 1125 | 4 | 5.45 ± 0.396 | |
1500 | 4 | 4.94 ± 0.339 | |||
1875 | 3 | 4.84 ± 0.676 |
Test Type | Start Date | Sample Time (h) | Species | Sex | Strain | Tissue | Protocol | Trend Test P |
---|---|---|---|---|---|---|---|---|
SCE | 12/17/86 | 23 | Mouse | Male | B6C3F1 | Bone Marrow | IP/IJ x 1, 23 hour |
Dose (mg/kg) | n | SCE / Cell (Mean ± SEM) | Pairwise P | ||
---|---|---|---|---|---|
Vehicle Control | Dimethyl Sulfoxide | 0 | 4 | 3.85 ± 0.092 | |
Test Chemical | HC blue 2 | 1500 | 4 | 6.72 ± 0.983 | |
Positive Control | Dimethylbenzanthracene | 2.5 | 4 | 9.53 ± 0.786 |
n: Number of animals analyzed