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Study Information
Study Attribute Value
CEBS Accession Number: 002-02324-0014-0000-8
Chemical Name: Isoprene
CASRN: 78-79-5
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: A63977_CA
Study Result: Negative (Nonstandard Protocol)

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 11/21/86 2 Mouse Male Bone Marrow Inhalation x 10/study, 2 weeks 0.3585
Test Group Dose
(ppm)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Test Chemical Isoprene 
438         
 8 3.75 ± 1.03 0.1068
  
1750         
 8 4.50 ± 1.30 0.0390
  
7000         
 8 3.50 ± 0.73 0.1451
Vehicle Control No Stressor 
 0         
 8 2.25 ± 0.70 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed