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Study Information
Study Attribute Value
CEBS Accession Number: 002-02349-0002-0000-2
Chemical Name: Lauric acid diethanolamine condensate
CASRN: 120-40-1
NTP Study Type: Genetic Toxicology - Mammalian Cell Cytogenetics
NTP Study ID: 836554_CA
Study Result: Negative

Study Result: Negative
Activation Trial Trial Call
No Activation  1  Negative 
Induced Rat Liver S9  1_S9  Negative 

Trial #:1   Activation: No Activation    Date: 11/13/1986    Harvest Time: 10 hour(s)   Trial Call: Negative   
  Dose
µg/mL		 Total
Cells Examined		 Total Aberrations Complex Aberrations Simple Aberrations Other Abs
No. of
Abs		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs
Vehicle Control: Solvent 
0         
 200 7 0.035 2.5 1 0.005 0.5 3 0.015 1.5 3 0.015 1.0
Test Chemical: Lauric acid diethanolamine condensate 
4.99      
 200 9 0.045 4.0 0 0.000 0.0 9 0.045 4.0 0 0.000 0.0 
15         
 200 3 0.015 1.5 3 0.015 1.5 0 0.000 0.0 0 0.000 0.0 
49.9       
 200 1 0.005 0.5 0 0.000 0.0 0 0.000 0.0 1 0.005 1.0 
100         
 0 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0
Positive Control: Mitomycin-C 
1         
 200 33 0.165 15.5 10 0.050 4.5 23 0.115 11.0 0 0.000 0.0
Mitomycin-C 
5         
 50 53 1.060 58.0 26 0.520 36.0 26 0.520 44.0 1 0.020 1.0
Trend: -1.913 -0.041 -2.369  
Probability: 0.972 0.516 0.991  


Trial #:1_S9   Activation: Induced Rat Liver S9    Date: 11/13/1986    Harvest Time: 12 hour(s)   Trial Call: Negative   
  Dose
µg/mL		 Total
Cells Examined		 Total Aberrations Complex Aberrations Simple Aberrations Other Abs
No. of
Abs		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs
Vehicle Control: Solvent 
0         
 200 10 0.050 4.0 4 0.020 2.0 6 0.030 3.0 0 0.000 0.0
Test Chemical: Lauric acid diethanolamine condensate 
1.5       
 200 9 0.045 3.5 1 0.005 0.5 8 0.040 3.5 0 0.000 0.0 
4.99      
 200 14 0.070 5.0 3 0.015 1.0 11 0.055 4.5 0 0.000 0.0 
15         
 200 9 0.045 3.5 1 0.005 0.5 7 0.035 2.5 1 0.005 1.0 
30         
 0 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0
Positive Control: Cyclophosphamide 
50         
 50 119 2.380 72.0 35 0.700 40.0 40 0.800 38.0 44 0.880 8.0
Trend: 0.015 -1.230 -0.091  
Probability: 0.494 0.891 0.536