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Study Information
Study Attribute Value
CEBS Accession Number: 002-02393-0012-0000-2
Chemical Name: Melamine
CASRN: 108-78-1
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 951364_CA
Study Result: Positive (Nonstandard Protocol)

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 02/07/89 36 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 36 hour 0.3583
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
25         
 8 5.75 ± 1.44 0.0000
Test Chemical Melamine 
150         
 8 1.25 ± 0.75 0.2386
  
300         
 8 2.50 ± 1.05 0.0251
  
600         
 8 1.00 ± 0.38 0.3521
Vehicle Control No Stressor 
 0         
 8 0.75 ± 0.37 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed