COVID-19 is an emerging, rapidly evolving situation.

Get the latest public health information from CDC and research information from NIH.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:
Study Information
Study Attribute Value
CEBS Accession Number: 002-02442-0012-0000-7
Chemical Name: Methyl methacrylate
CASRN: 80-62-6
NTP Study Type: Genetic Toxicology - Drosophila Germ Cell Mutagenicity
NTP Study ID: 901631_SLRL
Study Result: Negative

Table Instructions and Notes:

In some Drosophila SLRL studies, clusters (mutations concluded to result from a single spontaneous pre-meiotic event) in a single male were identified and all the data from that male were excluded from the study analysis. The published reports of these data present the adjusted values. The SLRL data on this web site are uncorrected for the removal of clusters. However, the overall conclusion of the study matches the published conclusion. If you require access to the corrected data, please refer to the associated journal or contact the NTP for a copy of the printed report.


Drosophilia Sex-Linked Recessive Lethal Study Details
Route of
Exposure		 Dose
(ppm)		 Percent
Mortality		 Percent
Sterility		 No. of Lethals / No. of X Chromosomes Tested Total Lethals / Total Tests Cluster Removed
Mating 1 Mating 2 Mating 3
Test Chemical 
14000         
 14 29 2/2431 4/1604 1/1730 7/5765 (0.12%) N
Vehicle Control 
 0         
 0/2862 2/2184 5/1748 7/6794 (0.10%) N
  P= 0.379
Test Chemical 
1400         
 53 0 2/1989 2/1981 1/1492 5/5462 (0.09%) Y
Vehicle Control 
 0         
 3/1737 2/1975 2/1482 7/5194 (0.13%) N
  P= 0.985
Abbreviations:
Br = Brood