COVID-19 is an emerging, rapidly evolving situation.

Get the latest public health information from CDC and research information from NIH.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:
Study Information
Study Attribute Value
CEBS Accession Number: 002-02479-0002-0000-6
Chemical Name: Mitomycin C
CASRN: 50-07-7
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: A55574_CA
Study Result: Positive (Nonstandard Protocol)

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 11/10/87 19 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 19 hour 0.0000
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Test Chemical Mitomycin C 
1         
 9 7.35 ± 0.30 0.0053
  
1.5       
 9 3.70 ± 0.56 0.0226
  
3.5       
 6 6.00 ± 2.16 0.0000
Vehicle Control No Stressor 
 0         
 10 0.25 ± 0.22 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed