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Study Information
Study Attribute Value
CEBS Accession Number: 002-02642-0008-0000-4
Chemical Name: Pentachloroethane
CASRN: 76-01-7
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 868606_CA
Study Result: Negative

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 08/31/87 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.2243
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
100         
 8 16.00 ± 1.81 0.0000
Test Chemical Pentachloroethane 
475         
 8 1.75 ± 0.70 0.8772
  
950         
 8 1.75 ± 0.45 0.8772
  
1900         
 8 3.50 ± 1.59 0.3450
Vehicle Control No Stressor 
 0         
 8 3.00 ± 0.38 0.0000


Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 05/12/92 36 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 36 hour 0.3443
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
25         
 8 21.50 ± 2.35 0.0000
Test Chemical Pentachloroethane 
325         
 8 1.00 ± 0.38 0.5000
  
650         
 8 1.25 ± 0.75 0.3687
  
1300         
 8 1.25 ± 0.53 0.3687
Vehicle Control No Stressor 
 0         
 8 1.00 ± 0.38 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed