Study Attribute | Value |
---|---|
CEBS Accession Number: | 002-02670-0013-0000-1 |
Chemical Name: | Phenol |
CASRN: | 108-95-2 |
NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
NTP Study ID: | 170681_CA |
Study Result: | Positive (Nonstandard Protocol) |
Test Type | Start Date | Sample Time (h) | Species | Sex | Tissue | Protocol | Trend Test P |
---|---|---|---|---|---|---|---|
CA | 02/11/86 | 17 | Mouse | Male | Bone Marrow | Intraperitoneal Injection x 1/study, 17 hour | 0.0000 |
Test Group | Dose (mg/kg) | n | Percent Cells w/ Aberrations (Mean ± SEM) | Pairwise P | |
---|---|---|---|---|---|
Positive Control | Mitomycin-C | 1 | 8 | 13.50 ± 1.95 | 0.0000 |
Test Chemical | Phenol | 75 | 8 | 1.50 ± 0.33 | 0.9480 |
150 | 8 | 3.50 ± 1.05 | 0.4224 | ||
300 | 8 | 8.75 ± 1.31 | 0.0005 | ||
Vehicle Control | No Stressor | 0 | 8 | 3.25 ± 0.84 | 0.0000 |
Footnotes: IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed
INHAL: Inhalation
n: Number of animals analyzed