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Study Information
Study Attribute Value
CEBS Accession Number: 002-02670-0015-0000-3
Chemical Name: Phenol
CASRN: 108-95-2
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 329606_CA
Study Result: Positive (Nonstandard Protocol)

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 08/09/86 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.0000
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Mitomycin-C 
1         
 8 7.50 ± 0.91 0.0006
Test Chemical Phenol 
75         
 8 2.25 ± 0.70 0.5918
  
150         
 8 1.75 ± 0.59 0.7690
  
300         
 8 8.75 ± 3.89 0.0001
Vehicle Control No Stressor 
 0         
 8 2.50 ± 0.73 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed