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Study Information
Study Attribute Value
CEBS Accession Number: 002-02671-0020-0000-0
Chemical Name: Phenolphthalein
CASRN: 77-09-8
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: A53649_CA
Study Result: Negative (Nonstandard Protocol)

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 08/15/96 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.0019
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
100         
 8 9.00 ± 1.00 0.0000
Test Chemical Phenolphthalein 
312.5       
 8 0.00 ± 0.00 0.5000
  
625         
 8 0.25 ± 0.25 0.1585
  
1250         
 8 0.25 ± 0.25 0.1585
  
2500         
 8 1.00 ± 0.38 0.0225
Vehicle Control No Stressor 
 0         
 8 0.00 ± 0.00 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed