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Study Information
Study Attribute Value
CEBS Accession Number: 002-02741-0013-0000-0
Chemical Name: Propiolactone
CASRN: 57-57-8
NTP Study Type: Genetic Toxicology - Drosophila Germ Cell Mutagenicity
NTP Study ID: 232716_RT
Study Result: Positive


You may also view: Sex-Linked Recessive Lethal Data for this study.


Drosophila Reciprocal Translocations Study Details
Route of Exposure Dose
ppm		 Solvent No. RTs / No. tests per sperm batch (in days of storage *) Total No. of Translocations Translocation
Frequency
(%)
0-3 3-7 7-10 10-14 14-17 17-20
Test Chemical 
1000         
 Normal Saline 0/1951 0/1617 0/1672 0/979 0/302 0/0 0/6521 0.00 
3000         
 Normal Saline 0/963 0/911 1/971 1/315 4/308 0/0 6/3468 0.17
 
Days of Storage: The number of days sperm were stored in the female before testing.