| Study Attribute | Value |
|---|---|
| CEBS Accession Number: | 002-02745-0012-0000-3 |
| Chemical Name: | Propyl gallate |
| CASRN: | 121-79-9 |
| NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
| NTP Study ID: | 299865_SCE |
| Study Result: | Negative (Nonstandard Protocol) |
Table Instructions and Notes:
Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.
| Test Type | Start Date | Sample Time (h) | Species | Sex | Strain | Tissue | Protocol | Trend Test P |
|---|---|---|---|---|---|---|---|---|
| SCE | 02/03/88 | 23 | Mouse | Male | B6C3F1 | Bone Marrow | IP/IJ x 1, 23 hour |
| Dose (mg/kg) | n | SCE / Cell (Mean ± SEM) | Pairwise P | ||
|---|---|---|---|---|---|
| Vehicle Control | Corn Oil | 0 | 4 | 6.64 ± 0.844 | |
| Test Chemical | Propyl gallate | 100 | 4 | 5.58 ± 0.382 | |
200 | 4 | 5.04 ± 0.629 | |||
400 | 4 | 6.24 ± 0.547 | |||
| Positive Control | Dimethylbenzanthracene | 2.5 | 4 | 5.17 ± 0.287 | |
| Test Type | Start Date | Sample Time (h) | Species | Sex | Strain | Tissue | Protocol | Trend Test P |
|---|---|---|---|---|---|---|---|---|
| SCE | 01/08/90 | 42 | Mouse | Male | B6C3F1 | Bone Marrow | IP/IJ x 1, 42 hour |
| Dose (mg/kg) | n | SCE / Cell (Mean ± SEM) | Pairwise P | ||
|---|---|---|---|---|---|
| Vehicle Control | Corn Oil | 0 | 4 | 4.83 ± 0.879 | |
| Test Chemical | Propyl gallate | 50 | 4 | 3.47 ± 0.257 | |
100 | 4 | 5.03 ± 0.631 | |||
200 | 4 | 4.51 ± 0.142 | |||
| Positive Control | Dimethylbenzanthracene | 2.5 | 4 | 9.92 ± 1.043 | |
Footnotes: IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed
n: Number of animals analyzed