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Study Information
Study Attribute Value
CEBS Accession Number: 002-02771-0001-0000-0
Chemical Name: Resorcinol
CASRN: 108-46-3
NTP Study Type: Genetic Toxicology - Mammalian Cell Cytogenetics
NTP Study ID: 101147_SCE
Study Result: Positive

Study Result: Positive
Activation Trial Trial Call
No Activation  1  Positive 
Induced Rat Liver S9  1_S9  Positive 

Trial #: 1    Activation: No Activation    Date: 03/08/1983    Trial Call: Positive   
  Dose
µg/mL		 Number
Cells
Examined		 Number
Chromosomes
Examined		 Total
Number
SCEs		 SCE /
Chromosome		 SCE /
Cell		 Hours in
BRDU		 % Increase
Over Solvent
Control
Vehicle Control Water 
0         
 50 1051 484 0.461 9.68 26.0 0.000
Test Chemical Resorcinol 
50         
 50 1045 508 0.486 10.16 26.0 5.561 
167         
 50 1030 904 0.878 18.08 32.5 90.585 
500         
 50 1032 1147 1.111 22.94 32.5 141.347 
1670         
 0 0 0 0.000 0.00 0.0 N/A
Positive Control Mitomycin-C 
 0.001     
 50 1048 742 0.708 14.84 26.0 53.745
Mitomycin-C 
 0.01      
 5 104 258 2.481 51.60 26.0 438.696
Trend: 19.744        
Probability: 0.000        

Trial #: 1_S9    Activation: Induced Rat Liver S9    Date: 03/08/1983    Trial Call: Positive   
  Dose
µg/mL		 Number
Cells
Examined		 Number
Chromosomes
Examined		 Total
Number
SCEs		 SCE /
Chromosome		 SCE /
Cell		 Hours in
BRDU		 % Increase
Over Solvent
Control
Vehicle Control Water 
0         
 50 1046 510 0.488 10.20 26.0 0.000
Test Chemical Resorcinol 
500         
 50 1047 501 0.479 10.02 26.0 -1.859 
1670         
 50 1045 623 0.596 12.46 26.0 22.274 
5000         
 50 1039 631 0.607 12.62 32.5 24.559
Positive Control Cyclophosphamide 
 0.3       
 50 1042 725 0.696 14.50 26.0 42.703
Cyclophosphamide 
2         
 5 105 201 1.914 40.20 26.0 292.616
Trend: 4.705        
Probability: 0.000