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Study Information
Study Attribute Value
CEBS Accession Number: 002-02771-0002-0000-1
Chemical Name: Resorcinol
CASRN: 108-46-3
NTP Study Type: Genetic Toxicology - Mammalian Cell Cytogenetics
NTP Study ID: 101147_CA
Study Result: Positive

Study Result: Positive
Activation Trial Trial Call
No Activation  1  Questionable 
Induced Rat Liver S9  1_S9  Positive 

Trial #:1   Activation: No Activation    Date: 03/23/1983    Harvest Time: 23.8 hour(s)   Trial Call: Questionable   
  Dose
µg/mL		 Total
Cells Examined		 Total Aberrations Complex Aberrations Simple Aberrations Other Abs
No. of
Abs		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs
Vehicle Control: Negative (Not Specified) 
0         
 100 3 0.030 3.0 1 0.010 1.0 2 0.020 2.0 0 0.000 0.0
Water 
0         
 100 2 0.020 2.0 0 0.000 0.0 1 0.010 1.0 1 0.010 1.0
Test Chemical: Resorcinol 
750         
 100 9 0.090 7.0 6 0.060 5.0 3 0.030 2.0 0 0.000 0.0 
1000         
 100 15 0.150 12.0 7 0.070 7.0 7 0.070 7.0 1 0.010 1.0 
1500         
 100 3 0.030 3.0 1 0.010 1.0 2 0.020 2.0 0 0.000 0.0 
2000         
 0 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0
Positive Control: Mitomycin-C 
 0.05      
 50 53 1.060 52.0 27 0.540 40.0 24 0.480 34.0 2 0.040 4.0
Trend: 0.536 0.437 0.868  
Probability: 0.296 0.331 0.193  


Trial #:1_S9   Activation: Induced Rat Liver S9    Date: 03/23/1983    Harvest Time: 23.8 hour(s)   Trial Call: Positive   
  Dose
µg/mL		 Total
Cells Examined		 Total Aberrations Complex Aberrations Simple Aberrations Other Abs
No. of
Abs		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs
Vehicle Control: Negative (Not Specified) 
0         
 100 3 0.030 3.0 2 0.020 2.0 1 0.010 1.0 0 0.000 0.0
Water 
0         
 100 4 0.040 3.0 2 0.020 2.0 1 0.010 1.0 1 0.010 1.0
Test Chemical: Resorcinol 
4000         
 100 46 0.460 13.0 7 0.070 5.0 8 0.080 5.0 31 0.310 4.0 
4500         
 100 41 0.410 12.0 16 0.160 8.0 3 0.030 3.0 22 0.220 4.0 
5000         
 100 59 0.590 21.0 32 0.320 19.0 17 0.170 11.0 10 0.100 1.0
Positive Control: Cyclophosphamide 
10         
 50 11 0.220 20.0 7 0.140 12.0 3 0.060 6.0 1 0.020 2.0
Trend: 3.592 4.300 2.834  
Probability: 0.000 0.000 0.002