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Study Information
Study Attribute Value
CEBS Accession Number: 002-02793-0020-0000-5
Chemical Name: Salicylazosulfapyridine
CASRN: 599-79-1
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 459882_CA
Study Result: Negative (Nonstandard Protocol)

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 07/07/88 20 Mouse Male Bone Marrow Gavage x 1/study, 20 hour 0.6773
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
100         
 8 2.75 ± 0.92 0.0018
Test Chemical Salicylazosulfapyridine 
250         
 8 0.75 ± 0.37 0.1580
  
500         
 8 1.75 ± 1.49 0.0165
  
1000         
 8 0.00 ± 0.00 0.8415
Vehicle Control No Stressor 
 0         
 8 0.25 ± 0.25 0.0000


Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 09/27/88 17 Mouse Male Bone Marrow Gavage x 1/study, 17 hour 0.9844
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
100         
 8 5.00 ± 1.51 0.0012
Test Chemical Salicylazosulfapyridine 
250         
 8 1.00 ± 0.65 0.6313
  
500         
 8 0.75 ± 0.37 0.7614
  
1000         
 8 0.00 ± 0.00 0.9876
Vehicle Control No Stressor 
 0         
 8 1.25 ± 0.53 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed