Study Attribute | Value |
---|---|
CEBS Accession Number: | 002-02793-0022-0000-7 |
Chemical Name: | Salicylazosulfapyridine |
CASRN: | 599-79-1 |
NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
NTP Study ID: | 724355_CA |
Study Result: | Negative (Nonstandard Protocol) |
Test Type | Start Date | Sample Time (h) | Species | Sex | Tissue | Protocol | Trend Test P |
---|---|---|---|---|---|---|---|
CA | 11/07/90 | 17 | Mouse | Male | Bone Marrow | Gavage x 1/study, 17 hour | 0.6026 |
Test Group | Dose (mg/kg) | n | Percent Cells w/ Aberrations (Mean ± SEM) | Pairwise P | |
---|---|---|---|---|---|
Positive Control | Mitomycin-C | 1 | 8 | 10.00 ± 2.24 | 0.0000 |
Test Chemical | Salicylazosulfapyridine | 1250 | 8 | 2.25 ± 0.96 | 0.4032 |
2500 | 8 | 2.75 ± 1.00 | 0.2430 | ||
5000 | 8 | 1.75 ± 0.96 | 0.6028 | ||
Vehicle Control | No Stressor | 0 | 8 | 2.00 ± 0.65 | 0.0000 |
Footnotes: IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed
INHAL: Inhalation
n: Number of animals analyzed