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Study Information
Study Attribute Value
CEBS Accession Number: 002-02793-0023-0000-8
Chemical Name: Salicylazosulfapyridine
CASRN: 599-79-1
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: A93691_CA
Study Result: Negative (Nonstandard Protocol)

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 01/23/92 24 Mouse Male Bone Marrow Gavage x 1/study, 24 hour 0.4638
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
150         
 8 8.00 ± 1.51 0.0000
Test Chemical Salicylazosulfapyridine 
1000         
 8 1.25 ± 0.53 0.1274
  
2000         
 8 1.00 ± 0.53 0.2062
  
4000         
 8 0.75 ± 0.37 0.3269
Vehicle Control No Stressor 
 0         
 8 0.50 ± 0.33 0.0000


Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 02/18/92 72 Mouse Male Bone Marrow Gavage x 3/study, 72 hour 0.9249
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
100         
 8 15.25 ± 3.14 0.0000
Test Chemical Salicylazosulfapyridine 
1000         
 8 0.50 ± 0.33 0.5000
  
2000         
 8 0.25 ± 0.25 0.7185
  
4000         
 8 0.00 ± 0.00 0.9216
Vehicle Control No Stressor 
 0         
 8 0.50 ± 0.33 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed