Study Attribute | Value |
---|---|
CEBS Accession Number: | 002-02797-0016-0000-4 |
Chemical Name: | Selenium sulfide |
CASRN: | 7446-34-6 |
NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
NTP Study ID: | A25043_CA |
Study Result: | Positive (Nonstandard Protocol) |
Test Type | Start Date | Sample Time (h) | Species | Sex | Tissue | Protocol | Trend Test P |
---|---|---|---|---|---|---|---|
CA | 11/12/91 | 36 | Mouse | Male | Bone Marrow | Intraperitoneal Injection x 1/study, 36 hour | 0.0000 |
Test Group | Dose (mg/kg) | n | Percent Cells w/ Aberrations (Mean ± SEM) | Pairwise P | |
---|---|---|---|---|---|
Positive Control | Dimethylbenzanthracene | 100 | 8 | 16.75 ± 3.18 | 0.0000 |
200 | 8 | 21.50 ± 1.40 | 0.0000 | ||
Test Chemical | Selenium sulfide | 5 | 8 | 2.00 ± 0.65 | 0.2949 |
10 | 8 | 3.25 ± 0.53 | 0.0520 | ||
20 | 8 | 9.25 ± 2.20 | 0.0000 | ||
Vehicle Control | No Stressor | 0 | 8 | 1.50 ± 0.50 | 0.0000 |
Footnotes: IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed
INHAL: Inhalation
n: Number of animals analyzed