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Study Information
Study Attribute Value
CEBS Accession Number: 002-02806-0001-0000-9
Chemical Name: Sodium (2-ethylhexyl)alcohol sulfate
CASRN: 126-92-1
NTP Study Type: Genetic Toxicology - Mammalian Cell Cytogenetics
NTP Study ID: 316678_SCE
Study Result: Negative

Study Result: Negative
Activation Trial Trial Call
No Activation  1  Negative 
Induced Rat Liver S9  1_S9  Negative 

Trial #: 1    Activation: No Activation    Date: 05/22/1985    Trial Call: Negative   
  Dose
µg/mL		 Number
Cells
Examined		 Number
Chromosomes
Examined		 Total
Number
SCEs		 SCE /
Chromosome		 SCE /
Cell		 Hours in
BRDU		 % Increase
Over Solvent
Control
Vehicle Control Medium 
0         
 50 1047 349 0.333 6.98 26.5 0.000
Test Chemical Sodium (2-ethylhexyl)alcohol sulfate 
149         
 50 1033 338 0.327 6.76 26.5 -1.839 
498         
 50 1045 362 0.346 7.24 26.5 3.923 
1490         
 50 1051 380 0.362 7.60 26.5 8.468
Positive Control Mitomycin-C 
 0.0015    
 50 1042 538 0.516 10.76 26.5 54.894
Mitomycin-C 
 0.01      
 10 207 283 1.367 28.30 26.5 310.145
Trend: 1.283        
Probability: 0.100        

Trial #: 1_S9    Activation: Induced Rat Liver S9    Date: 05/22/1985    Trial Call: Negative   
  Dose
µg/mL		 Number
Cells
Examined		 Number
Chromosomes
Examined		 Total
Number
SCEs		 SCE /
Chromosome		 SCE /
Cell		 Hours in
BRDU		 % Increase
Over Solvent
Control
Vehicle Control Medium 
0         
 50 1049 441 0.420 8.82 25.5 0.000
Test Chemical Sodium (2-ethylhexyl)alcohol sulfate 
498         
 50 1054 414 0.393 8.28 25.5 -6.568 
1490         
 50 1047 430 0.411 8.60 25.5 -2.308 
4980         
 50 1051 482 0.459 9.64 25.5 9.089
Positive Control Cyclophosphamide 
 0.4       
 50 1047 777 0.742 15.54 25.5 76.527
Cyclophosphamide 
2.5       
 10 210 380 1.810 38.00 25.5 330.429
Trend: 1.501        
Probability: 0.067