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Study Information
Study Attribute Value
CEBS Accession Number: 002-02806-0006-0000-4
Chemical Name: Sodium (2-ethylhexyl)alcohol sulfate
CASRN: 126-92-1
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 795640_SCE
Study Result: Positive


Table Instructions and Notes:

Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.


Summary of Sister Chromatid Exchange Data (Trial 1)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 05/05/87 23 Mouse Male B6C3F1 Bone Marrow IP/IJ x 1,  23 hour
  Dose
(mg/kg)		 n SCE / Cell
(Mean ± SEM)		 Pairwise P
Vehicle Control Phosphate Buffered Saline 
 0         
 4 3.62 ± 0.539
Test Chemical Sodium (2-ethylhexyl)alcohol sulfate 
275         
 4 4.39 ± 0.292
  
550         
 4 4.99 ± 0.473
  
1100         
 4 6.29 ± 0.539
Positive Control Mitomycin-C 
 0.5       
 4 8.28 ± 1.426


Summary of Sister Chromatid Exchange Data (Trial 2)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 08/01/88 23 Mouse Male B6C3F1 Bone Marrow IP/IJ x 1,  23 hour
  Dose
(mg/kg)		 n SCE / Cell
(Mean ± SEM)		 Pairwise P
Vehicle Control Phosphate Buffered Saline 
 0         
 4 4.25 ± 0.568
Test Chemical Sodium (2-ethylhexyl)alcohol sulfate 
825         
 4 7.41 ± 1.022
  
1100         
 4 7.77 ± 1.388
Positive Control Mitomycin-C 
1         
 4 6.76 ± 0.169


Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed