COVID-19 is an emerging, rapidly evolving situation.

Get the latest public health information from CDC and research information from NIH.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:
Study Information
Study Attribute Value
CEBS Accession Number: 002-02857-0010-0000-5
Chemical Name: Sulfapyridine
CASRN: 144-83-2
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: A49990_CA
Study Result: Negative (Nonstandard Protocol)

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 01/16/92 24 Mouse Male Bone Marrow Gavage x 1/study, 24 hour 0.0000
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
150         
 0 0.00 ± 0.00 0.0000
Test Chemical Sulfapyridine 
500         
 0 0.00 ± 0.00 0.0000
  
1000         
 0 0.00 ± 0.00 0.0000
  
2000         
 0 0.00 ± 0.00 0.0000
Vehicle Control No Stressor 
 0         
 0 0.00 ± 0.00 0.0000


Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 02/11/92 72 Mouse Male Bone Marrow Gavage x 3/study, 72 hour 0.8234
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
100         
 8 15.75 ± 2.09 0.0000
Test Chemical Sulfapyridine 
500         
 8 1.00 ± 0.38 0.8777
  
1000         
 8 6.45 ± 0.56 0.6728
  
2000         
 8 1.00 ± 0.53 0.8777
Vehicle Control No Stressor 
 0         
 8 2.00 ± 0.53 0.0000


Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 12/22/92 17 Mouse Male Bone Marrow Gavage x 1/study, 17 hour 0.6841
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
100         
 8 3.75 ± 2.02 0.0002
Test Chemical Sulfapyridine 
500         
 8 1.00 ± 0.53 0.0892
  
1000         
 8 0.50 ± 0.33 0.2815
  
2000         
 8 0.25 ± 0.25 0.5000
Vehicle Control No Stressor 
 0         
 8 0.25 ± 0.25 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed