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Study Information
Study Attribute Value
CEBS Accession Number: 002-02877-0012-0000-9
Chemical Name: Tetrachlorophthalic anhydride
CASRN: 117-08-8
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 927311_SCE
Study Result: Positive (Nonstandard Protocol)


Table Instructions and Notes:

Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.


Summary of Sister Chromatid Exchange Data (Trial 1)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 06/12/84 23 Mouse Male B6C3F1 Bone Marrow IP/IJ x 1,  23 hour
  Dose
(mg/kg)		 n SCE / Cell
(Mean ± SEM)		 Pairwise P
Vehicle Control Dimethyl Sulfoxide 
 0         
 4 4.47 ± 0.658
Test Chemical Tetrachlorophthalic anhydride 
100         
 4 5.40 ± 0.197
  
200         
 4 5.70 ± 0.298
  
400         
 4 6.52 ± 0.963
Positive Control Dimethylbenzanthracene 
10         
 4 12.79 ± 0.932


Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed