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Study Information
Study Attribute Value
CEBS Accession Number: 002-02877-0013-0000-0
Chemical Name: Tetrachlorophthalic anhydride
CASRN: 117-08-8
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 927311_CA
Study Result: Negative (Nonstandard Protocol)

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 06/29/84 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.6760
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
200         
 8 18.75 ± 3.21 0.0000
Test Chemical Tetrachlorophthalic anhydride 
100         
 8 0.50 ± 0.33 0.9719
  
200         
 8 1.25 ± 0.65 0.7992
  
400         
 8 1.25 ± 0.53 0.7992
Vehicle Control No Stressor 
 0         
 8 2.00 ± 1.25 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed