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Study Information
Study Attribute Value
CEBS Accession Number: 002-02930-0002-0000-8
Chemical Name: Triallyl isocyanurate
CASRN: 1025-15-6
NTP Study Type: Genetic Toxicology - Mammalian Cell Cytogenetics
NTP Study ID: 652546_CA
Study Result: Negative

Study Result: Negative
Activation Trial Trial Call
No Activation  1  Negative 
Induced Rat Liver S9  1_S9  Negative 

Trial #:1   Activation: No Activation    Date: 05/20/1986    Harvest Time: 10.5 hour(s)   Trial Call: Negative   
  Dose
µg/mL		 Total
Cells Examined		 Total Aberrations Complex Aberrations Simple Aberrations Other Abs
No. of
Abs		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs
Vehicle Control: Dimethyl Sulfoxide 
0         
 200 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0
Test Chemical: Triallyl isocyanurate 
146         
 200 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0 
485         
 200 2 0.010 0.5 0 0.000 0.0 2 0.010 0.5 0 0.000 0.0 
1460         
 200 1 0.005 0.5 1 0.005 0.5 0 0.000 0.0 0 0.000 0.0
Positive Control: Mitomycin-C 
 0.75      
 400 57 0.143 12.0 35 0.088 8.0 22 0.055 4.8 0 0.000 0.0
Mitomycin-C 
5         
 50 23 0.460 26.0 13 0.260 24.0 10 0.200 14.0 0 0.000 0.0
Trend: 1.274 1.327 0.474  
Probability: 0.101 0.092 0.318  


Trial #:1_S9   Activation: Induced Rat Liver S9    Date: 05/20/1986    Harvest Time: 12 hour(s)   Trial Call: Negative   
  Dose
µg/mL		 Total
Cells Examined		 Total Aberrations Complex Aberrations Simple Aberrations Other Abs
No. of
Abs		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs
Vehicle Control: Dimethyl Sulfoxide 
0         
 200 10 0.050 4.0 0 0.000 0.0 10 0.050 4.0 0 0.000 0.0
Test Chemical: Triallyl isocyanurate 
291         
 200 4 0.020 2.0 0 0.000 0.0 3 0.015 1.5 1 0.005 1.0 
970         
 200 5 0.025 2.5 1 0.005 0.5 3 0.015 1.5 1 0.005 1.0 
2910         
 200 8 0.040 3.5 1 0.005 0.5 7 0.035 3.0 0 0.000 0.0
Positive Control: Cyclophosphamide 
50         
 50 23 0.460 38.0 7 0.140 14.0 14 0.280 22.0 2 0.040 2.0
Trend: -0.193 1.275 -0.623  
Probability: 0.576 0.101 0.733