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Study Information
Study Attribute Value
CEBS Accession Number: 002-02945-0025-0000-9
Chemical Name: Trichloroethylene
CASRN: 79-01-6
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 316661_SCE
Study Result: Negative (Nonstandard Protocol)


Table Instructions and Notes:

Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.


Summary of Sister Chromatid Exchange Data (Trial 1)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 10/22/87 23 Mouse Male B6C3F1 Bone Marrow IP/IJ x 1,  23 hour
  Dose
(mg/kg)
n SCE / Cell
(Mean ± SEM)
Pairwise P
Vehicle Control Corn Oil
 0         
4 3.37 ± 0.363
Test Chemical Trichloroethylene
1250         
4 3.43 ± 0.325
 
2500         
4 3.38 ± 0.268
 
5000         
3 3.50 ± 0.069
Positive Control Dimethylbenzanthracene
100         
4 6.25 ± 0.491


Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed