COVID-19 is an emerging, rapidly evolving situation.

Get the latest public health information from CDC and research information from NIH.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:
Study Information
Study Attribute Value
CEBS Accession Number: 002-02945-0026-0000-0
Chemical Name: Trichloroethylene
CASRN: 79-01-6
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 316661_CA
Study Result: Negative

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 10/20/87 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.7305
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
100         
 8 16.25 ± 1.67 0.0000
Test Chemical Trichloroethylene 
1250         
 8 2.50 ± 0.33 0.7372
  
2500         
 8 3.25 ± 1.19 0.5000
  
5000         
 7 2.29 ± 0.81 0.7877
Vehicle Control No Stressor 
 0         
 8 3.25 ± 1.06 0.0000


Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 08/20/91 36 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 36 hour 0.3594
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
50         
 8 28.25 ± 2.19 0.0000
Test Chemical Trichloroethylene 
750         
 6 2.33 ± 0.80 0.4709
  
1500         
 8 3.00 ± 1.41 0.2535
  
3000         
 7 2.57 ± 0.57 0.3871
Vehicle Control No Stressor 
 0         
 8 2.25 ± 0.88 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed