Study Attribute | Value |
---|---|
CEBS Accession Number: | 002-02951-0002-0000-1 |
Chemical Name: | Triethanolamine |
CASRN: | 102-71-6 |
NTP Study Type: | Genetic Toxicology - Mammalian Cell Cytogenetics |
NTP Study ID: | 932037_CA |
Study Result: | Negative |
Activation | Trial | Trial Call |
---|---|---|
No Activation | 1 | Negative |
Induced Rat Liver S9 | 1_S9 | Negative |
Dose µg/mL | Total Cells Examined | Total Aberrations | Complex Aberrations | Simple Aberrations | Other Abs | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
No. of Abs | Abs Per Cell | % Cells With Abs | No. of Abs. | Abs Per Cell | % Cells With Abs | No. of Abs. | Abs Per Cell | % Cells With Abs | No. of Abs. | Abs Per Cell | % Cells With Abs | ||||
Vehicle Control: | Negative (Not Specified) | 0 | 100 | 6 | 0.060 | 6.0 | 2 | 0.020 | 2.0 | 2 | 0.020 | 2.0 | 2 | 0.020 | 2.0 |
Dimethyl Sulfoxide | 0 | 100 | 7 | 0.070 | 5.0 | 3 | 0.030 | 2.0 | 4 | 0.040 | 3.0 | 0 | 0.000 | 0.0 | |
Test Chemical: | Triethanolamine | 1510 | 100 | 2 | 0.020 | 2.0 | 1 | 0.010 | 1.0 | 1 | 0.010 | 1.0 | 0 | 0.000 | 0.0 |
2010 | 100 | 1 | 0.010 | 1.0 | 1 | 0.010 | 1.0 | 0 | 0.000 | 0.0 | 0 | 0.000 | 0.0 | ||
4030 | 56 | 0 | 0.000 | 0.0 | 0 | 0.000 | 0.0 | 0 | 0.000 | 0.0 | 0 | 0.000 | 0.0 | ||
Positive Control: | Mitomycin-C | 0.5 | 100 | 24 | 0.240 | 20.0 | 14 | 0.140 | 13.0 | 9 | 0.090 | 8.0 | 1 | 0.010 | 1.0 |
Trend: | -2.181 | -1.129 | -1.938 | ||||||||||||
Probability: | 0.985 | 0.870 | 0.974 |
Dose µg/mL | Total Cells Examined | Total Aberrations | Complex Aberrations | Simple Aberrations | Other Abs | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
No. of Abs | Abs Per Cell | % Cells With Abs | No. of Abs. | Abs Per Cell | % Cells With Abs | No. of Abs. | Abs Per Cell | % Cells With Abs | No. of Abs. | Abs Per Cell | % Cells With Abs | ||||
Vehicle Control: | Negative (Not Specified) | 0 | 100 | 5 | 0.050 | 2.0 | 2 | 0.020 | 1.0 | 3 | 0.030 | 1.0 | 0 | 0.000 | 0.0 |
Dimethyl Sulfoxide | 0 | 100 | 2 | 0.020 | 2.0 | 0 | 0.000 | 0.0 | 1 | 0.010 | 1.0 | 1 | 0.010 | 1.0 | |
Test Chemical: | Triethanolamine | 6040 | 100 | 3 | 0.030 | 3.0 | 2 | 0.020 | 2.0 | 1 | 0.010 | 1.0 | 0 | 0.000 | 0.0 |
8060 | 100 | 6 | 0.060 | 5.0 | 1 | 0.010 | 1.0 | 4 | 0.040 | 4.0 | 1 | 0.010 | 1.0 | ||
10070 | 100 | 2 | 0.020 | 2.0 | 1 | 0.010 | 1.0 | 1 | 0.010 | 0.0 | 0 | 0.000 | 0.0 | ||
Positive Control: | Cyclophosphamide | 25 | 100 | 32 | 0.320 | 26.0 | 20 | 0.200 | 16.0 | 11 | 0.110 | 11.0 | 1 | 0.010 | 1.0 |
Trend: | 0.325 | 0.443 | 0.117 | ||||||||||||
Probability: | 0.373 | 0.329 | 0.453 |