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Study Information
Study Attribute Value
CEBS Accession Number: 002-02951-0002-0000-1
Chemical Name: Triethanolamine
CASRN: 102-71-6
NTP Study Type: Genetic Toxicology - Mammalian Cell Cytogenetics
NTP Study ID: 932037_CA
Study Result: Negative

Study Result: Negative
Activation Trial Trial Call
No Activation  Negative 
Induced Rat Liver S9  1_S9  Negative 

Trial #:1   Activation: No Activation    Date: 11/03/1981    Harvest Time: 10.5 hour(s)   Trial Call: Negative   
  Dose
µg/mL
Total
Cells Examined
Total Aberrations Complex Aberrations Simple Aberrations Other Abs
No. of
Abs
Abs
Per
Cell
% Cells
With
Abs
No. of
Abs.
Abs
Per
Cell
% Cells
With
Abs
No. of
Abs.
Abs
Per
Cell
% Cells
With
Abs
No. of
Abs.
Abs
Per
Cell
% Cells
With
Abs
Vehicle Control: Negative (Not Specified)
0         
100 6 0.060 6.0 2 0.020 2.0 2 0.020 2.0 2 0.020 2.0
Dimethyl Sulfoxide
0         
100 7 0.070 5.0 3 0.030 2.0 4 0.040 3.0 0 0.000 0.0
Test Chemical: Triethanolamine
1510         
100 2 0.020 2.0 1 0.010 1.0 1 0.010 1.0 0 0.000 0.0
2010         
100 1 0.010 1.0 1 0.010 1.0 0 0.000 0.0 0 0.000 0.0
4030         
56 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0
Positive Control: Mitomycin-C
 0.5       
100 24 0.240 20.0 14 0.140 13.0 9 0.090 8.0 1 0.010 1.0
Trend: -2.181 -1.129 -1.938  
Probability: 0.985 0.870 0.974  


Trial #:1_S9   Activation: Induced Rat Liver S9    Date: 11/03/1981    Harvest Time: 10.5 hour(s)   Trial Call: Negative   
  Dose
µg/mL
Total
Cells Examined
Total Aberrations Complex Aberrations Simple Aberrations Other Abs
No. of
Abs
Abs
Per
Cell
% Cells
With
Abs
No. of
Abs.
Abs
Per
Cell
% Cells
With
Abs
No. of
Abs.
Abs
Per
Cell
% Cells
With
Abs
No. of
Abs.
Abs
Per
Cell
% Cells
With
Abs
Vehicle Control: Negative (Not Specified)
0         
100 5 0.050 2.0 2 0.020 1.0 3 0.030 1.0 0 0.000 0.0
Dimethyl Sulfoxide
0         
100 2 0.020 2.0 0 0.000 0.0 1 0.010 1.0 1 0.010 1.0
Test Chemical: Triethanolamine
6040         
100 3 0.030 3.0 2 0.020 2.0 1 0.010 1.0 0 0.000 0.0
8060         
100 6 0.060 5.0 1 0.010 1.0 4 0.040 4.0 1 0.010 1.0
10070         
100 2 0.020 2.0 1 0.010 1.0 1 0.010 0.0 0 0.000 0.0
Positive Control: Cyclophosphamide
25         
100 32 0.320 26.0 20 0.200 16.0 11 0.110 11.0 1 0.010 1.0
Trend: 0.325 0.443 0.117  
Probability: 0.373 0.329 0.453