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Study Information
Study Attribute Value
CEBS Accession Number: 002-03058-0022-0000-2
Chemical Name: trans-1,2-Dichloroethylene
CASRN: 156-60-5
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 560707_CA
Study Result: Negative (Nonstandard Protocol)

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 01/23/85 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.5661
Test Group Dose
(mg/kg)
n Percent Cells w/ Aberrations
(Mean ± SEM)
Pairwise P
Positive Control Dimethylbenzanthracene
100         
8 21.00 ± 2.85 0.0000
Test Chemical trans-1,2-Dichloroethylene
500         
8 1.75 ± 1.03 0.6932
 
1000         
8 3.75 ± 1.91 0.1068
 
2000         
8 1.75 ± 0.80 0.6932
Vehicle Control No Stressor
 0         
8 2.25 ± 0.45 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed