Study Attribute | Value |
---|---|
CEBS Accession Number: | 002-03058-0022-0000-2 |
Chemical Name: | trans-1,2-Dichloroethylene |
CASRN: | 156-60-5 |
NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
NTP Study ID: | 560707_CA |
Study Result: | Negative (Nonstandard Protocol) |
Test Type | Start Date | Sample Time (h) | Species | Sex | Tissue | Protocol | Trend Test P |
---|---|---|---|---|---|---|---|
CA | 01/23/85 | 17 | Mouse | Male | Bone Marrow | Intraperitoneal Injection x 1/study, 17 hour | 0.5661 |
Test Group | Dose (mg/kg) | n | Percent Cells w/ Aberrations (Mean ± SEM) | Pairwise P | |
---|---|---|---|---|---|
Positive Control | Dimethylbenzanthracene | 100 | 8 | 21.00 ± 2.85 | 0.0000 |
Test Chemical | trans-1,2-Dichloroethylene | 500 | 8 | 1.75 ± 1.03 | 0.6932 |
1000 | 8 | 3.75 ± 1.91 | 0.1068 | ||
2000 | 8 | 1.75 ± 0.80 | 0.6932 | ||
Vehicle Control | No Stressor | 0 | 8 | 2.25 ± 0.45 | 0.0000 |
Footnotes: IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed
INHAL: Inhalation
n: Number of animals analyzed