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Chemical Name: | 1,2,4,5-Tetrachlorobenzene |
---|---|
CASRN: | ="95-94-3" |
Study Number: | C61949 |
Study Length (Year Completed): | 13 Weeks (N/A) |
Exposure Route: | FEED |
TDMS Number: | 0516404.ss |
Sex: | Female |
Strain and Species: | B6C3F1 Mice |
Clinical Chemistry Individual Animal Data | ||||||||
---|---|---|---|---|---|---|---|---|
Measurement Time | Animal Number | Dose Group (ppm) | Control Code | Creat (U per L) | ALB (g_dL) | Creat Kinase (IU_L) | ALT (IU_L) | SDH (IU_L) |
Week 13 | 4291 | 0 | V | 1.13 | 2.7 | 254 | 32 | 18 |
Week 13 | 4292 | 0 | V | 0.92 | 3.1 | 143 | 21 | 17 |
Week 13 | 4293 | 0 | V | 1.03 | 3.4 | 278 | 28 | 16 |
Week 13 | 4294 | 0 | V | 0.97 | 3.5 | 92 | 29 | 16 |
Week 13 | 4295 | 0 | V | 0.46 | 3 | 275 | 40 | 16 |
Week 13 | 4296 | 0 | V | 0.99 | 3 | 72 | ||
Week 13 | 4297 | 0 | V | 0.67 | 3.4 | 113 | 30 | 15 |
Week 13 | 4298 | 0 | V | 0.48 | 3.1 | 375 | 16 | 14 |
Week 13 | 4299 | 0 | V | 0.37 | 3.1 | 763 | 21 | 13 |
Week 13 | 4300 | 0 | V | 0.45 | 3 | 326 | 23 | 16 |
Week 13 | 4301 | 30 | 0.99 | 3 | 97 | 23 | 17 | |
Week 13 | 4302 | 30 | 0.99 | 3.2 | 153 | 26 | 19 | |
Week 13 | 4303 | 30 | 3.3 | 1368 | 38 | 25 | ||
Week 13 | 4304 | 30 | 1.38 | 3.3 | 113 | 26 | 17 | |
Week 13 | 4305 | 30 | 1.66 | 3.2 | 637 | 24 | 25 | |
Week 13 | 4306 | 30 | 1.27 | 3.3 | 322 | 27 | 30 | |
Week 13 | 4307 | 30 | 0.39 | 3.2 | 247 | 18 | 14 | |
Week 13 | 4308 | 30 | 0.66 | 3.5 | 136 | 19 | 19 | |
Week 13 | 4309 | 30 | 0.45 | 3.3 | 44 | 23 | 17 | |
Week 13 | 4310 | 30 | 0.41 | 3.3 | 29 | 18 | 17 | |
Week 13 | 4311 | 100 | 1.12 | 3.5 | 18 | 160 | 14 | |
Week 13 | 4312 | 100 | 1.5 | 3.4 | 189 | 34 | 19 | |
Week 13 | 4313 | 100 | 0.81 | 3.7 | 258 | 33 | ||
Week 13 | 4314 | 100 | 3.3 | 332 | 36 | 20 | ||
Week 13 | 4315 | 100 | 0.67 | 3 | 351 | 28 | 13 | |
Week 13 | 4316 | 100 | 0.42 | 3 | 257 | 12 | 16 | |
Week 13 | 4317 | 100 | 0.4 | 3.4 | 416 | 26 | 18 | |
Week 13 | 4318 | 100 | 0.46 | 3.1 | 196 | 30 | 21 | |
Week 13 | 4319 | 100 | 0.69 | 3.3 | 132 | 33 | 16 | |
Week 13 | 4320 | 100 | 0.49 | 3.3 | 447 | 11 | 15 | |
Week 13 | 4321 | 300 | 1.07 | 3 | 89 | 22 | 20 | |
Week 13 | 4322 | 300 | 0.42 | 3 | 13 | 41 | ||
Week 13 | 4323 | 300 | 1.06 | 3.1 | 57 | 21 | 15 | |
Week 13 | 4324 | 300 | 1.5 | 3.2 | 643 | 59 | 32 | |
Week 13 | 4325 | 300 | 1.52 | 3.5 | 466 | 60 | 26 | |
Week 13 | 4326 | 300 | 0.42 | 3.1 | 700 | 44 | 17 | |
Week 13 | 4327 | 300 | 0.81 | 3.1 | 1682 | 30 | 19 | |
Week 13 | 4328 | 300 | 0.44 | 3.1 | 75 | 18 | 12 | |
Week 13 | 4329 | 300 | 0.44 | 3.2 | 27 | 13 | 19 | |
Week 13 | 4330 | 300 | 0.5 | 3 | 210 | 22 | 16 | |
Week 13 | 4331 | 1000 | 0.65 | 2.8 | 67 | 21 | 35 | |
Week 13 | 4332 | 1000 | 2.34 | 3.3 | 176 | 31 | 29 | |
Week 13 | 4333 | 1000 | 1.36 | 3.1 | 272 | 45 | 30 | |
Week 13 | 4334 | 1000 | 3.2 | 77 | 10 | 9 | ||
Week 13 | 4335 | 1000 | 2.13 | 3.1 | 824 | 42 | 29 | |
Week 13 | 4336 | 1000 | 0.68 | 3.1 | 87 | 19 | 26 | |
Week 13 | 4337 | 1000 | 1.39 | 3.4 | 215 | 31 | 34 | |
Week 13 | 4338 | 1000 | 0.92 | 3.2 | 640 | 34 | 28 | |
Week 13 | 4339 | 1000 | 0.36 | 3.2 | 254 | 49 | 35 | |
Week 13 | 4340 | 1000 | 0.41 | 3.1 | 187 | 32 | 28 | |
Week 13 | 4341 | 2000 | 0.54 | 3.8 | 22 | 11 | 63 | |
Week 13 | 4342 | 2000 | 0.85 | 4.4 | 169 | 92 | 86 | |
Week 13 | 4343 | 2000 | 1.97 | 4 | 131 | 152 | 107 | |
Week 13 | 4344 | 2000 | 1.79 | 3.5 | 264 | 68 | 60 | |
Week 13 | 4346 | 2000 | 0.4 | 3.9 | 404 | 182 | 124 | |
Week 13 | 4347 | 2000 | 0.5 | 4 | 50 | 96 | 93 | |
Week 13 | 4349 | 2000 | 0.49 | 4.1 | 52 | 59 | 73 | |
Week 13 | 4350 | 2000 | 0.44 | 4.3 | 318 | 73 | 100 | |
Abbreviations: | ||||||||
NA: Not Available, V: Vehicle Control, Creat: Creatinine, ALB: Albumin, Creat Kinase: Creatine Kinase, ALT: Alanine Aminotransferase, SDH: Sorbitol Dehydrogenase |