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Short-Term Individual Animal Non Neoplastic Diagnosis
Study Information:
Chemical Name: | 1,2-Dibromo-2,4-dicyanobutane |
CASRN: | ="35691-65-7" |
Study Number: | C97003B |
Exposure Route: | SKIN APPLICATION |
TDMS Number: | 9700302 |
Sex: | Female |
Strain and Species: | B6C3F1 Mice |
Female Individual Animal Non Neoplastic Diagnoses
System |
Organ |
Site |
Treatment Group |
Number Examined |
Cage Number |
Animal Number |
Days on Study |
Lesion Found |
Lesion Name |
Lesion Qualifier |
Removal Reason |
Hematopoietic System |
Lymph Node |
Mandibular |
Vehicle Control |
1 |
35 |
35 |
17 |
1 |
Hyperplasia |
Moderate, Diffuse |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
1200 MG/KG |
1 |
59 |
59 |
17 |
1 |
Hematopoietic Cell Proliferation |
Marked, Diffuse |
Terminal Sacrifice |
Integumentary System |
Skin |
Dermis, SOA |
75 MG/KG |
5 |
36 |
36 |
17 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
Dermis, SOA |
75 MG/KG |
5 |
37 |
37 |
17 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
Dermis, SOA |
75 MG/KG |
5 |
38 |
38 |
17 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
Dermis, SOA |
75 MG/KG |
5 |
39 |
39 |
17 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
Dermis, SOA |
150 MG/KG |
5 |
41 |
41 |
17 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
Dermis, SOA |
150 MG/KG |
5 |
42 |
42 |
17 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
Dermis, SOA |
150 MG/KG |
5 |
43 |
43 |
17 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
Dermis, SOA |
150 MG/KG |
5 |
44 |
44 |
17 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
Dermis, SOA |
150 MG/KG |
5 |
45 |
45 |
17 |
1 |
Necrosis |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Dermis, SOA |
300 MG/KG |
5 |
46 |
46 |
17 |
1 |
Necrosis |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Dermis, SOA |
300 MG/KG |
5 |
47 |
47 |
17 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
Dermis, SOA |
300 MG/KG |
5 |
48 |
48 |
17 |
1 |
Necrosis |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Dermis, SOA |
300 MG/KG |
5 |
49 |
49 |
17 |
1 |
Necrosis |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Dermis, SOA |
300 MG/KG |
5 |
50 |
50 |
17 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
Dermis, SOA |
600 MG/KG |
5 |
52 |
52 |
17 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
Dermis, SOA |
600 MG/KG |
5 |
54 |
54 |
17 |
1 |
Necrosis |
Marked |
Terminal Sacrifice |
Integumentary System |
Skin |
Dermis, SOA |
600 MG/KG |
5 |
55 |
55 |
17 |
1 |
Necrosis |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Dermis, SOA |
1200 MG/KG |
5 |
56 |
56 |
17 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
Dermis, SOA |
1200 MG/KG |
5 |
57 |
57 |
17 |
1 |
Necrosis |
Marked |
Terminal Sacrifice |
Integumentary System |
Skin |
Dermis, SOA |
1200 MG/KG |
5 |
58 |
58 |
17 |
1 |
Necrosis |
Marked |
Terminal Sacrifice |
Integumentary System |
Skin |
Dermis, SOA |
1200 MG/KG |
5 |
59 |
59 |
17 |
1 |
Necrosis |
Marked |
Terminal Sacrifice |
Integumentary System |
Skin |
Dermis, SOA |
1200 MG/KG |
5 |
60 |
60 |
17 |
1 |
Necrosis |
Marked |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
Vehicle Control |
5 |
31 |
31 |
17 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
75 MG/KG |
5 |
36 |
36 |
17 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
75 MG/KG |
5 |
37 |
37 |
17 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
75 MG/KG |
5 |
38 |
38 |
17 |
1 |
Hyperplasia |
Marked |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
75 MG/KG |
5 |
39 |
39 |
17 |
1 |
Hyperplasia |
Marked |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
75 MG/KG |
5 |
40 |
40 |
17 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
150 MG/KG |
5 |
41 |
41 |
17 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
150 MG/KG |
5 |
42 |
42 |
17 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
150 MG/KG |
5 |
43 |
43 |
17 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
150 MG/KG |
5 |
44 |
44 |
17 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
150 MG/KG |
5 |
45 |
45 |
17 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
300 MG/KG |
5 |
46 |
46 |
17 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
300 MG/KG |
5 |
47 |
47 |
17 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
300 MG/KG |
5 |
48 |
48 |
17 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
300 MG/KG |
5 |
49 |
49 |
17 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
300 MG/KG |
5 |
50 |
50 |
17 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
600 MG/KG |
5 |
51 |
51 |
17 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
600 MG/KG |
5 |
52 |
52 |
17 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
600 MG/KG |
5 |
53 |
53 |
17 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
600 MG/KG |
5 |
54 |
54 |
17 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
600 MG/KG |
5 |
55 |
55 |
17 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
1200 MG/KG |
5 |
56 |
56 |
17 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
1200 MG/KG |
5 |
57 |
57 |
17 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
1200 MG/KG |
5 |
58 |
58 |
17 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
1200 MG/KG |
5 |
59 |
59 |
17 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
1200 MG/KG |
5 |
60 |
60 |
17 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
75 MG/KG |
5 |
36 |
36 |
17 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
75 MG/KG |
5 |
37 |
37 |
17 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
75 MG/KG |
5 |
38 |
38 |
17 |
1 |
Necrosis |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
75 MG/KG |
5 |
39 |
39 |
17 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
75 MG/KG |
5 |
40 |
40 |
17 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
150 MG/KG |
5 |
41 |
41 |
17 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
150 MG/KG |
5 |
42 |
42 |
17 |
1 |
Necrosis |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
150 MG/KG |
5 |
43 |
43 |
17 |
1 |
Necrosis |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
150 MG/KG |
5 |
44 |
44 |
17 |
1 |
Necrosis |
Marked |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
150 MG/KG |
5 |
45 |
45 |
17 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
300 MG/KG |
5 |
46 |
46 |
17 |
1 |
Necrosis |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
300 MG/KG |
5 |
47 |
47 |
17 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
300 MG/KG |
5 |
48 |
48 |
17 |
1 |
Necrosis |
Marked |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
300 MG/KG |
5 |
49 |
49 |
17 |
1 |
Necrosis |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
300 MG/KG |
5 |
50 |
50 |
17 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
600 MG/KG |
5 |
52 |
52 |
17 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
600 MG/KG |
5 |
53 |
53 |
17 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
600 MG/KG |
5 |
54 |
54 |
17 |
1 |
Necrosis |
Marked |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
600 MG/KG |
5 |
55 |
55 |
17 |
1 |
Necrosis |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
1200 MG/KG |
5 |
56 |
56 |
17 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
1200 MG/KG |
5 |
57 |
57 |
17 |
1 |
Necrosis |
Marked |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
1200 MG/KG |
5 |
58 |
58 |
17 |
1 |
Necrosis |
Marked |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
1200 MG/KG |
5 |
59 |
59 |
17 |
1 |
Necrosis |
Marked |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
1200 MG/KG |
5 |
60 |
60 |
17 |
1 |
Necrosis |
Marked |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
75 MG/KG |
5 |
38 |
38 |
17 |
1 |
Ulcer |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
75 MG/KG |
5 |
39 |
39 |
17 |
1 |
Ulcer |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
150 MG/KG |
5 |
41 |
41 |
17 |
1 |
Ulcer |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
150 MG/KG |
5 |
43 |
43 |
17 |
1 |
Ulcer |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
150 MG/KG |
5 |
44 |
44 |
17 |
1 |
Ulcer |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
150 MG/KG |
5 |
45 |
45 |
17 |
1 |
Ulcer |
Marked |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
300 MG/KG |
5 |
46 |
46 |
17 |
1 |
Ulcer |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
300 MG/KG |
5 |
48 |
48 |
17 |
1 |
Ulcer |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
600 MG/KG |
5 |
51 |
51 |
17 |
1 |
Ulcer |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
600 MG/KG |
5 |
52 |
52 |
17 |
1 |
Ulcer |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
600 MG/KG |
5 |
53 |
53 |
17 |
1 |
Ulcer |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
600 MG/KG |
5 |
54 |
54 |
17 |
1 |
Ulcer |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
600 MG/KG |
5 |
55 |
55 |
17 |
1 |
Ulcer |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
1200 MG/KG |
5 |
56 |
56 |
17 |
1 |
Ulcer |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
1200 MG/KG |
5 |
58 |
58 |
17 |
1 |
Ulcer |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
1200 MG/KG |
5 |
59 |
59 |
17 |
1 |
Ulcer |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis, SOA |
1200 MG/KG |
5 |
60 |
60 |
17 |
1 |
Ulcer |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
75 MG/KG |
5 |
36 |
36 |
17 |
1 |
Hyperkeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
75 MG/KG |
5 |
37 |
37 |
17 |
1 |
Hyperkeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
75 MG/KG |
5 |
38 |
38 |
17 |
1 |
Hyperkeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
75 MG/KG |
5 |
39 |
39 |
17 |
1 |
Hyperkeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
75 MG/KG |
5 |
40 |
40 |
17 |
1 |
Hyperkeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
150 MG/KG |
5 |
41 |
41 |
17 |
1 |
Hyperkeratosis |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
150 MG/KG |
5 |
42 |
42 |
17 |
1 |
Hyperkeratosis |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
150 MG/KG |
5 |
43 |
43 |
17 |
1 |
Hyperkeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
150 MG/KG |
5 |
44 |
44 |
17 |
1 |
Hyperkeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
150 MG/KG |
5 |
45 |
45 |
17 |
1 |
Hyperkeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
300 MG/KG |
5 |
47 |
47 |
17 |
1 |
Hyperkeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
300 MG/KG |
5 |
48 |
48 |
17 |
1 |
Hyperkeratosis |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
300 MG/KG |
5 |
49 |
49 |
17 |
1 |
Hyperkeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
300 MG/KG |
5 |
50 |
50 |
17 |
1 |
Hyperkeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
600 MG/KG |
5 |
51 |
51 |
17 |
1 |
Hyperkeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
600 MG/KG |
5 |
52 |
52 |
17 |
1 |
Hyperkeratosis |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
600 MG/KG |
5 |
53 |
53 |
17 |
1 |
Hyperkeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
600 MG/KG |
5 |
54 |
54 |
17 |
1 |
Hyperkeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
600 MG/KG |
5 |
55 |
55 |
17 |
1 |
Hyperkeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
1200 MG/KG |
5 |
56 |
56 |
17 |
1 |
Hyperkeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
1200 MG/KG |
5 |
57 |
57 |
17 |
1 |
Hyperkeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
1200 MG/KG |
5 |
58 |
58 |
17 |
1 |
Hyperkeratosis |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
1200 MG/KG |
5 |
59 |
59 |
17 |
1 |
Hyperkeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
1200 MG/KG |
5 |
60 |
60 |
17 |
1 |
Hyperkeratosis |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
Vehicle Control |
5 |
34 |
34 |
17 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
75 MG/KG |
5 |
36 |
36 |
17 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
75 MG/KG |
5 |
37 |
37 |
17 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
75 MG/KG |
5 |
38 |
38 |
17 |
1 |
Inflammation |
Moderate, Chronic Active |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
75 MG/KG |
5 |
39 |
39 |
17 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
75 MG/KG |
5 |
40 |
40 |
17 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
150 MG/KG |
5 |
41 |
41 |
17 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
150 MG/KG |
5 |
42 |
42 |
17 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
150 MG/KG |
5 |
43 |
43 |
17 |
1 |
Inflammation |
Moderate, Chronic Active |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
150 MG/KG |
5 |
44 |
44 |
17 |
1 |
Inflammation |
Moderate, Chronic Active |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
150 MG/KG |
5 |
45 |
45 |
17 |
1 |
Inflammation |
Moderate, Chronic Active |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
300 MG/KG |
5 |
46 |
46 |
17 |
1 |
Inflammation |
Moderate, Chronic Active |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
300 MG/KG |
5 |
47 |
47 |
17 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
300 MG/KG |
5 |
48 |
48 |
17 |
1 |
Inflammation |
Moderate, Chronic Active |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
300 MG/KG |
5 |
49 |
49 |
17 |
1 |
Inflammation |
Moderate, Chronic Active |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
300 MG/KG |
5 |
50 |
50 |
17 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
600 MG/KG |
5 |
51 |
51 |
17 |
1 |
Inflammation |
Moderate, Chronic Active |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
600 MG/KG |
5 |
52 |
52 |
17 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
600 MG/KG |
5 |
53 |
53 |
17 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
600 MG/KG |
5 |
54 |
54 |
17 |
1 |
Inflammation |
Moderate, Chronic Active |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
600 MG/KG |
5 |
55 |
55 |
17 |
1 |
Inflammation |
Moderate, Chronic Active |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
1200 MG/KG |
5 |
56 |
56 |
17 |
1 |
Inflammation |
Moderate, Chronic Active |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
1200 MG/KG |
5 |
57 |
57 |
17 |
1 |
Inflammation |
Marked, Chronic Active |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
1200 MG/KG |
5 |
58 |
58 |
17 |
1 |
Inflammation |
Marked, Chronic Active |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
1200 MG/KG |
5 |
59 |
59 |
17 |
1 |
Inflammation |
Marked, Chronic Active |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
1200 MG/KG |
5 |
60 |
60 |
17 |
1 |
Inflammation |
Moderate, Chronic Active |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
75 MG/KG |
5 |
36 |
36 |
17 |
1 |
Parakeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
75 MG/KG |
5 |
37 |
37 |
17 |
1 |
Parakeratosis |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
75 MG/KG |
5 |
38 |
38 |
17 |
1 |
Parakeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
75 MG/KG |
5 |
39 |
39 |
17 |
1 |
Parakeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
75 MG/KG |
5 |
40 |
40 |
17 |
1 |
Parakeratosis |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
150 MG/KG |
5 |
41 |
41 |
17 |
1 |
Parakeratosis |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
150 MG/KG |
5 |
42 |
42 |
17 |
1 |
Parakeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
150 MG/KG |
5 |
43 |
43 |
17 |
1 |
Parakeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
300 MG/KG |
5 |
46 |
46 |
17 |
1 |
Parakeratosis |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
300 MG/KG |
5 |
47 |
47 |
17 |
1 |
Parakeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
300 MG/KG |
5 |
48 |
48 |
17 |
1 |
Parakeratosis |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
300 MG/KG |
5 |
49 |
49 |
17 |
1 |
Parakeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
300 MG/KG |
5 |
50 |
50 |
17 |
1 |
Parakeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
600 MG/KG |
5 |
51 |
51 |
17 |
1 |
Parakeratosis |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
600 MG/KG |
5 |
52 |
52 |
17 |
1 |
Parakeratosis |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
600 MG/KG |
5 |
53 |
53 |
17 |
1 |
Parakeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
600 MG/KG |
5 |
54 |
54 |
17 |
1 |
Parakeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
600 MG/KG |
5 |
55 |
55 |
17 |
1 |
Parakeratosis |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
1200 MG/KG |
5 |
56 |
56 |
17 |
1 |
Parakeratosis |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
1200 MG/KG |
5 |
57 |
57 |
17 |
1 |
Parakeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
1200 MG/KG |
5 |
58 |
58 |
17 |
1 |
Parakeratosis |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA |
1200 MG/KG |
5 |
60 |
60 |
17 |
1 |
Parakeratosis |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA, Sebaceous Gl |
75 MG/KG |
5 |
36 |
36 |
17 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA, Sebaceous Gl |
75 MG/KG |
5 |
37 |
37 |
17 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA, Sebaceous Gl |
75 MG/KG |
5 |
38 |
38 |
17 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA, Sebaceous Gl |
75 MG/KG |
5 |
39 |
39 |
17 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA, Sebaceous Gl |
75 MG/KG |
5 |
40 |
40 |
17 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA, Sebaceous Gl |
150 MG/KG |
5 |
41 |
41 |
17 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA, Sebaceous Gl |
150 MG/KG |
5 |
42 |
42 |
17 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA, Sebaceous Gl |
150 MG/KG |
5 |
44 |
44 |
17 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA, Sebaceous Gl |
150 MG/KG |
5 |
45 |
45 |
17 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA, Sebaceous Gl |
300 MG/KG |
5 |
46 |
46 |
17 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA, Sebaceous Gl |
300 MG/KG |
5 |
48 |
48 |
17 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA, Sebaceous Gl |
300 MG/KG |
5 |
49 |
49 |
17 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA, Sebaceous Gl |
300 MG/KG |
5 |
50 |
50 |
17 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA, Sebaceous Gl |
600 MG/KG |
5 |
51 |
51 |
17 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA, Sebaceous Gl |
600 MG/KG |
5 |
52 |
52 |
17 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA, Sebaceous Gl |
600 MG/KG |
5 |
53 |
53 |
17 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA, Sebaceous Gl |
600 MG/KG |
5 |
54 |
54 |
17 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA, Sebaceous Gl |
1200 MG/KG |
5 |
56 |
56 |
17 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
SOA, Sebaceous Gl |
1200 MG/KG |
5 |
57 |
57 |
17 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |