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Short-Term Study
Organ Weights Individual Animal
Study Information:
Chemical Name: | 2',3'-Dideoxycytidine |
CASRN: | ="7481-89-2" |
Study Number: | C88073C |
Study Length (Year Completed): |
(N/A) |
Exposure Route: | GAVAGE |
TDMS Number: | 8807304 |
Sex: | Female |
Strain and Species: | B6C3F1 Mice |
Organ Weights Individual Animal Data |
Measurement Time |
Animal Number |
Dose Group () |
Control Code |
Final Body Weight |
Final Body Weight (g) |
Day 141 |
345 |
1000 |
|
25.9 |
|
Day 148 |
352 |
1000 |
|
27.1 |
|
Day 162 |
344 |
1000 |
|
35.1 |
|
Day 162 |
376 |
1000 |
|
36.8 |
|
Day 162 |
390 |
1000 |
|
|
|
Day 169 |
355 |
1000 |
|
35 |
|
Day 169 |
357 |
1000 |
|
25.2 |
|
Day 173 |
331 |
1000 |
|
25.8 |
|
Day 183 |
395 |
1000 |
|
29.1 |
|
Day 187 |
251 |
500 |
|
39.2 |
|
Day 187 |
252 |
500 |
|
35.7 |
|
Day 187 |
253 |
500 |
|
29.1 |
|
Day 187 |
254 |
500 |
|
43.2 |
|
Day 187 |
255 |
500 |
|
41.7 |
|
Day 187 |
256 |
500 |
|
35.7 |
|
Day 187 |
257 |
500 |
|
34.9 |
|
Day 187 |
258 |
500 |
|
42.8 |
|
Day 187 |
259 |
500 |
|
38.5 |
|
Day 187 |
260 |
500 |
|
36.8 |
|
Day 187 |
261 |
500 |
|
39.5 |
|
Day 187 |
262 |
500 |
|
37.1 |
|
Day 187 |
263 |
500 |
|
36 |
|
Day 187 |
264 |
500 |
|
36.6 |
|
Day 187 |
265 |
500 |
|
30.9 |
|
Day 187 |
266 |
500 |
|
38.2 |
|
Day 187 |
267 |
500 |
|
38.9 |
|
Day 187 |
268 |
500 |
|
40.1 |
|
Day 187 |
269 |
500 |
|
44.3 |
|
Day 187 |
270 |
500 |
|
37.9 |
|
Day 187 |
271 |
500 |
|
38.6 |
|
Day 187 |
272 |
500 |
|
37 |
|
Day 187 |
273 |
500 |
|
36.6 |
|
Day 187 |
274 |
500 |
|
39.2 |
|
Day 187 |
275 |
500 |
|
37.7 |
|
Day 187 |
276 |
500 |
|
43.5 |
|
Day 187 |
277 |
500 |
|
37.4 |
|
Day 187 |
278 |
500 |
|
39.2 |
|
Day 187 |
279 |
500 |
|
42.7 |
|
Day 187 |
280 |
500 |
|
41.3 |
|
Day 187 |
281 |
500 |
|
36.4 |
|
Day 187 |
282 |
500 |
|
32.8 |
|
Day 187 |
283 |
500 |
|
35.8 |
|
Day 187 |
284 |
500 |
|
37 |
|
Day 187 |
285 |
500 |
|
40.7 |
|
Day 187 |
286 |
500 |
|
44.1 |
|
Day 187 |
301 |
1000 |
|
28.9 |
|
Day 187 |
302 |
1000 |
|
31.9 |
|
Day 187 |
303 |
1000 |
|
36.7 |
|
Day 187 |
304 |
1000 |
|
33.7 |
|
Day 187 |
305 |
1000 |
|
29.6 |
|
Day 187 |
306 |
1000 |
|
29.4 |
|
Day 187 |
307 |
1000 |
|
31.5 |
|
Day 187 |
308 |
1000 |
|
29.6 |
|
Day 187 |
309 |
1000 |
|
31.3 |
|
Day 187 |
310 |
1000 |
|
28.5 |
|
Day 187 |
311 |
1000 |
|
33.5 |
|
Day 187 |
312 |
1000 |
|
29.1 |
|
Day 187 |
313 |
1000 |
|
30.7 |
|
Day 187 |
314 |
1000 |
|
31.5 |
|
Day 187 |
315 |
1000 |
|
32.9 |
|
Day 187 |
316 |
1000 |
|
33.7 |
|
Day 187 |
317 |
1000 |
|
32 |
|
Day 187 |
318 |
1000 |
|
31 |
|
Day 187 |
319 |
1000 |
|
31 |
|
Day 187 |
320 |
1000 |
|
31.8 |
|
Day 187 |
321 |
1000 |
|
32 |
|
Day 187 |
322 |
1000 |
|
32.4 |
|
Day 187 |
323 |
1000 |
|
30.6 |
|
Day 187 |
324 |
1000 |
|
32.3 |
|
Day 187 |
325 |
1000 |
|
30.8 |
|
Day 187 |
326 |
1000 |
|
30.7 |
|
Day 187 |
327 |
1000 |
|
35.9 |
|
Day 187 |
328 |
1000 |
|
34.8 |
|
Day 187 |
329 |
1000 |
|
31.4 |
|
Day 187 |
330 |
1000 |
|
35 |
|
Day 187 |
332 |
1000 |
|
33.8 |
|
Day 187 |
333 |
1000 |
|
31.8 |
|
Day 187 |
334 |
1000 |
|
27.8 |
|
Day 187 |
335 |
1000 |
|
30.5 |
|
Day 187 |
336 |
1000 |
|
36.3 |
|
Day 187 |
337 |
1000 |
|
29.9 |
|
Day 188 |
201 |
0 |
|
35.1 |
|
Day 188 |
202 |
0 |
|
41.1 |
|
Day 188 |
203 |
0 |
|
38.1 |
|
Day 188 |
204 |
0 |
|
39.6 |
|
Day 188 |
205 |
0 |
|
40.9 |
|
Day 188 |
206 |
0 |
|
38.1 |
|
Day 188 |
207 |
0 |
|
41.9 |
|
Day 188 |
208 |
0 |
|
42.7 |
|
Day 188 |
209 |
0 |
|
39.7 |
|
Day 188 |
210 |
0 |
|
39.6 |
|
Day 188 |
211 |
0 |
|
38.1 |
|
Day 188 |
212 |
0 |
|
40.2 |
|
Day 188 |
213 |
0 |
|
39.3 |
|
Day 188 |
214 |
0 |
|
42.4 |
|
Day 188 |
215 |
0 |
|
40.4 |
|
Day 188 |
216 |
0 |
|
38.7 |
|
Day 188 |
217 |
0 |
|
40.1 |
|
Day 188 |
218 |
0 |
|
41.7 |
|
Day 188 |
219 |
0 |
|
39.5 |
|
Day 188 |
220 |
0 |
|
39 |
|
Day 188 |
221 |
0 |
|
37 |
|
Day 188 |
222 |
0 |
|
44.1 |
|
Day 188 |
223 |
0 |
|
36.7 |
|
Day 188 |
224 |
0 |
|
39.9 |
|
Day 188 |
225 |
0 |
|
42.8 |
|
Day 188 |
287 |
500 |
|
36.8 |
|
Day 188 |
288 |
500 |
|
36.7 |
|
Day 188 |
289 |
500 |
|
40.1 |
|
Day 188 |
290 |
500 |
|
37.2 |
|
Day 188 |
291 |
500 |
|
35.2 |
|
Day 188 |
292 |
500 |
|
38.2 |
|
Day 188 |
293 |
500 |
|
37 |
|
Day 188 |
294 |
500 |
|
39.9 |
|
Day 188 |
295 |
500 |
|
43.1 |
|
Day 188 |
296 |
500 |
|
39.5 |
|
Day 188 |
297 |
500 |
|
38 |
|
Day 188 |
298 |
500 |
|
37.9 |
|
Day 188 |
299 |
500 |
|
33.7 |
|
Day 188 |
300 |
500 |
|
40.4 |
|
Day 188 |
338 |
1000 |
|
29.4 |
|
Day 188 |
339 |
1000 |
|
28.7 |
|
Day 188 |
340 |
1000 |
|
30.3 |
|
Day 188 |
341 |
1000 |
|
32.5 |
|
Day 188 |
342 |
1000 |
|
27.5 |
|
Day 188 |
343 |
1000 |
|
32.5 |
|
Day 188 |
346 |
1000 |
|
29.6 |
|
Day 188 |
347 |
1000 |
|
39.4 |
|
Day 188 |
348 |
1000 |
|
29.8 |
|
Day 188 |
349 |
1000 |
|
28.4 |
|
Day 188 |
350 |
1000 |
|
31.9 |
|
Day 189 |
226 |
0 |
|
38.2 |
|
Day 189 |
227 |
0 |
|
40.9 |
|
Day 189 |
228 |
0 |
|
35.9 |
|
Day 189 |
229 |
0 |
|
47.6 |
|
Day 189 |
230 |
0 |
|
39.2 |
|
Day 189 |
231 |
0 |
|
37.2 |
|
Day 189 |
232 |
0 |
|
44 |
|
Day 189 |
233 |
0 |
|
43.5 |
|
Day 189 |
234 |
0 |
|
43 |
|
Day 189 |
235 |
0 |
|
41.7 |
|
Day 189 |
236 |
0 |
|
43.8 |
|
Day 189 |
237 |
0 |
|
40.1 |
|
Day 189 |
238 |
0 |
|
40.5 |
|
Day 189 |
239 |
0 |
|
45.2 |
|
Day 189 |
240 |
0 |
|
40.5 |
|
Day 189 |
241 |
0 |
|
38.8 |
|
Day 189 |
242 |
0 |
|
44.7 |
|
Day 189 |
243 |
0 |
|
38.7 |
|
Day 189 |
244 |
0 |
|
38 |
|
Day 189 |
245 |
0 |
|
42 |
|
Day 189 |
246 |
0 |
|
41.3 |
|
Day 189 |
247 |
0 |
|
39.6 |
|
Day 189 |
248 |
0 |
|
39.7 |
|
Day 189 |
249 |
0 |
|
43.5 |
|
Day 189 |
250 |
0 |
|
38.7 |
|
Day 189 |
351 |
1000 |
|
40 |
|
Day 189 |
353 |
1000 |
|
40.7 |
|
Day 189 |
354 |
1000 |
|
43.3 |
|
Day 189 |
356 |
1000 |
|
38.2 |
|
Day 189 |
358 |
1000 |
|
41.1 |
|
Day 189 |
359 |
1000 |
|
47.9 |
|
Day 189 |
360 |
1000 |
|
31.9 |
|
Day 189 |
361 |
1000 |
|
38.6 |
|
Day 189 |
362 |
1000 |
|
45.5 |
|
Day 189 |
363 |
1000 |
|
43.8 |
|
Day 189 |
364 |
1000 |
|
48.2 |
|
Day 189 |
365 |
1000 |
|
46 |
|
Day 189 |
366 |
1000 |
|
45.5 |
|
Day 189 |
367 |
1000 |
|
36.7 |
|
Day 189 |
368 |
1000 |
|
44.1 |
|
Day 189 |
369 |
1000 |
|
43 |
|
Day 189 |
370 |
1000 |
|
42.4 |
|
Day 189 |
371 |
1000 |
|
42.6 |
|
Day 189 |
372 |
1000 |
|
43.6 |
|
Day 189 |
373 |
1000 |
|
44.9 |
|
Day 189 |
374 |
1000 |
|
48.3 |
|
Day 189 |
375 |
1000 |
|
38.9 |
|
Day 189 |
377 |
1000 |
|
42.3 |
|
Day 189 |
378 |
1000 |
|
33.1 |
|
Day 189 |
379 |
1000 |
|
49.8 |
|
Day 189 |
380 |
1000 |
|
36 |
|
Day 189 |
381 |
1000 |
|
47.2 |
|
Day 189 |
382 |
1000 |
|
44.5 |
|
Day 189 |
383 |
1000 |
|
40.3 |
|
Day 189 |
384 |
1000 |
|
44.4 |
|
Day 189 |
385 |
1000 |
|
40.4 |
|
Day 189 |
386 |
1000 |
|
32.6 |
|
Day 189 |
387 |
1000 |
|
42.3 |
|
Day 189 |
388 |
1000 |
|
43.3 |
|
Day 189 |
389 |
1000 |
|
41.9 |
|
Day 189 |
391 |
1000 |
|
42.8 |
|
Day 189 |
392 |
1000 |
|
42.6 |
|
Day 189 |
393 |
1000 |
|
40.2 |
|
Day 189 |
394 |
1000 |
|
45.3 |
|
Day 189 |
396 |
1000 |
|
49.8 |
|
Day 189 |
397 |
1000 |
|
41.3 |
|
Day 189 |
398 |
1000 |
|
42.7 |
|
Day 189 |
399 |
1000 |
|
44.9 |
|
Day 189 |
400 |
1000 |
|
41.7 |
|
Abbreviations: |
NA: Not Available
|