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Long-Term Study
Organ Weights Individual Animal
Study Information:
Chemical Name: | 2,2-bis(Bromomethyl)-1,3-propanediol |
CASRN: | ="3296-90-0" |
Study Number: | C55516C |
Study Length (Year Completed): |
(N/A) |
Exposure Route: | DOSED FEED |
TDMS Number: | 0510305 |
Sex: | Female |
Strain and Species: | F 344/N Rats |
Organ Weights Individual Animal Data |
Measurement Time |
Animal Number |
Dose Group (%) |
Control Code |
Final Body Weight |
Final Body Weight (g) |
Day 369 |
503 |
1.00 |
|
|
|
Day 388 |
500 |
0.50 |
|
255.8 |
|
Day 404 |
425 |
0.25 |
|
208.2 |
|
Day 409 |
488 |
0.50 |
|
191.9 |
|
Day 432 |
489 |
0.50 |
|
197.4 |
|
Day 432 |
508 |
1.00 |
|
272.4 |
|
Day 456 |
371 |
0 |
|
274.7 |
|
Day 456 |
372 |
0 |
|
288 |
|
Day 456 |
373 |
0 |
|
291.1 |
|
Day 456 |
374 |
0 |
|
330.2 |
|
Day 456 |
375 |
0 |
|
275.6 |
|
Day 456 |
376 |
0 |
|
301.3 |
|
Day 456 |
377 |
0 |
|
314.6 |
|
Day 456 |
378 |
0 |
|
295.4 |
|
Day 456 |
379 |
0 |
|
301.7 |
|
Day 456 |
380 |
0 |
|
294.1 |
|
Day 456 |
432 |
0.25 |
|
304 |
|
Day 456 |
433 |
0.25 |
|
282.9 |
|
Day 456 |
434 |
0.25 |
|
284.5 |
|
Day 456 |
435 |
0.25 |
|
265.9 |
|
Day 456 |
436 |
0.25 |
|
281.9 |
|
Day 456 |
437 |
0.25 |
|
281.3 |
|
Day 456 |
438 |
0.25 |
|
255.2 |
|
Day 456 |
439 |
0.25 |
|
280.9 |
|
Day 456 |
440 |
0.25 |
|
247.1 |
|
Day 456 |
493 |
0.50 |
|
289.2 |
|
Day 456 |
494 |
0.50 |
|
295.2 |
|
Day 456 |
495 |
0.50 |
|
256.8 |
|
Day 456 |
496 |
0.50 |
|
273.3 |
|
Day 456 |
497 |
0.50 |
|
253 |
|
Day 456 |
498 |
0.50 |
|
302.1 |
|
Day 456 |
499 |
0.50 |
|
286 |
|
Day 456 |
553 |
1.00 |
|
236.9 |
|
Day 456 |
554 |
1.00 |
|
284.3 |
|
Day 456 |
555 |
1.00 |
|
279.4 |
|
Day 456 |
556 |
1.00 |
|
269.9 |
|
Day 456 |
557 |
1.00 |
|
289.3 |
|
Day 456 |
558 |
1.00 |
|
320.4 |
|
Day 456 |
559 |
1.00 |
|
281.7 |
|
Day 456 |
560 |
1.00 |
|
283.4 |
|
Day 460 |
330 |
0 |
|
300.6 |
|
Day 460 |
383 |
0.25 |
|
268.6 |
|
Day 460 |
535 |
1.00 |
|
291.7 |
|
Day 474 |
549 |
1.00 |
|
255.7 |
|
Day 481 |
332 |
0 |
|
266.2 |
|
Day 481 |
457 |
0.50 |
|
254.7 |
|
Day 508 |
460 |
0.50 |
|
|
|
Day 509 |
429 |
0.25 |
|
310.8 |
|
Day 509 |
546 |
1.00 |
|
267.7 |
|
Day 516 |
331 |
0 |
|
337.7 |
|
Day 516 |
536 |
1.00 |
|
292.4 |
|
Day 523 |
543 |
1.00 |
|
228.1 |
|
Day 540 |
523 |
1.00 |
|
|
|
Day 551 |
501 |
1.00 |
|
297.9 |
|
Day 565 |
452 |
0.50 |
|
244.2 |
|
Day 574 |
520 |
1.00 |
|
|
|
Day 576 |
448 |
0.50 |
|
366.1 |
|
Day 577 |
551 |
1.00 |
|
235.5 |
|
Day 585 |
468 |
0.50 |
|
|
|
Day 585 |
505 |
1.00 |
|
306.2 |
|
Day 585 |
524 |
1.00 |
|
306.6 |
|
Day 592 |
538 |
1.00 |
|
339.5 |
|
Day 592 |
544 |
1.00 |
|
320.6 |
|
Day 594 |
517 |
1.00 |
|
|
|
Day 598 |
522 |
1.00 |
|
221.3 |
|
Day 609 |
409 |
0.25 |
|
171.7 |
|
Day 610 |
442 |
0.50 |
|
304.1 |
|
Day 610 |
514 |
1.00 |
|
374.6 |
|
Day 610 |
552 |
1.00 |
|
304.4 |
|
Day 619 |
410 |
0.25 |
|
208.6 |
|
Day 619 |
513 |
1.00 |
|
337.5 |
|
Day 624 |
341 |
0 |
|
249.1 |
|
Day 625 |
506 |
1.00 |
|
380.5 |
|
Day 625 |
509 |
1.00 |
|
222.2 |
|
Day 627 |
475 |
0.50 |
|
210.4 |
|
Day 627 |
527 |
1.00 |
|
328.6 |
|
Day 630 |
504 |
1.00 |
|
258.9 |
|
Day 631 |
447 |
0.50 |
|
231.9 |
|
Day 631 |
502 |
1.00 |
|
290.4 |
|
Day 631 |
516 |
1.00 |
|
302.3 |
|
Day 632 |
480 |
0.50 |
|
208.1 |
|
Day 633 |
333 |
0 |
|
251.1 |
|
Day 633 |
487 |
0.50 |
|
367.8 |
|
Day 634 |
518 |
1.00 |
|
306.3 |
|
Day 645 |
394 |
0.25 |
|
323.5 |
|
Day 645 |
510 |
1.00 |
|
250.3 |
|
Day 654 |
354 |
0 |
|
209.8 |
|
Day 656 |
386 |
0.25 |
|
188.7 |
|
Day 659 |
547 |
1.00 |
|
213.2 |
|
Day 660 |
459 |
0.50 |
|
260.5 |
|
Day 660 |
526 |
1.00 |
|
257.8 |
|
Day 660 |
534 |
1.00 |
|
305 |
|
Day 662 |
463 |
0.50 |
|
240.6 |
|
Day 670 |
464 |
0.50 |
|
203.1 |
|
Day 670 |
467 |
0.50 |
|
373.7 |
|
Day 670 |
525 |
1.00 |
|
294.2 |
|
Day 673 |
490 |
0.50 |
|
284 |
|
Day 676 |
412 |
0.25 |
|
|
|
Day 680 |
392 |
0.25 |
|
|
|
Day 680 |
521 |
1.00 |
|
|
|
Day 682 |
462 |
0.50 |
|
343.9 |
|
Day 682 |
511 |
1.00 |
|
273.9 |
|
Day 682 |
533 |
1.00 |
|
244.1 |
|
Day 683 |
391 |
0.25 |
|
298.1 |
|
Day 683 |
491 |
0.50 |
|
364.1 |
|
Day 683 |
537 |
1.00 |
|
317.4 |
|
Day 683 |
540 |
1.00 |
|
306 |
|
Day 684 |
407 |
0.25 |
|
235 |
|
Day 684 |
424 |
0.25 |
|
214.9 |
|
Day 684 |
512 |
1.00 |
|
317.7 |
|
Day 684 |
548 |
1.00 |
|
254.5 |
|
Day 689 |
349 |
0 |
|
370.3 |
|
Day 689 |
507 |
1.00 |
|
306.7 |
|
Day 690 |
361 |
0 |
|
202.9 |
|
Day 694 |
353 |
0 |
|
363.7 |
|
Day 694 |
450 |
0.50 |
|
401.3 |
|
Day 694 |
532 |
1.00 |
|
281.4 |
|
Day 694 |
542 |
1.00 |
|
290.4 |
|
Day 695 |
384 |
0.25 |
|
354.6 |
|
Day 695 |
419 |
0.25 |
|
305.8 |
|
Day 695 |
466 |
0.50 |
|
329.7 |
|
Day 695 |
484 |
0.50 |
|
324.1 |
|
Day 696 |
346 |
0 |
|
205.7 |
|
Day 696 |
367 |
0 |
|
222 |
|
Day 696 |
453 |
0.50 |
|
246.9 |
|
Day 697 |
405 |
0.25 |
|
294.9 |
|
Day 697 |
446 |
0.50 |
|
325 |
|
Day 697 |
458 |
0.50 |
|
351.2 |
|
Day 701 |
417 |
0.25 |
|
369 |
|
Day 704 |
423 |
0.25 |
|
266.6 |
|
Day 704 |
485 |
0.50 |
|
291.5 |
|
Day 708 |
323 |
0 |
|
253.6 |
|
Day 709 |
398 |
0.25 |
|
221 |
|
Day 709 |
545 |
1.00 |
|
279.4 |
|
Day 716 |
329 |
0 |
|
228.9 |
|
Day 719 |
397 |
0.25 |
|
331.8 |
|
Day 719 |
481 |
0.50 |
|
206.8 |
|
Day 722 |
358 |
0 |
|
262.5 |
|
Day 722 |
415 |
0.25 |
|
204.6 |
|
Day 722 |
529 |
1.00 |
|
250.4 |
|
Day 723 |
388 |
0.25 |
|
229.6 |
|
Day 723 |
404 |
0.25 |
|
256.9 |
|
Day 725 |
385 |
0.25 |
|
409 |
|
Day 725 |
387 |
0.25 |
|
351.3 |
|
Day 725 |
519 |
1.00 |
|
281.5 |
|
Day 725 |
550 |
1.00 |
|
312.6 |
|
Day 726 |
451 |
0.50 |
|
349.2 |
|
Day 726 |
541 |
1.00 |
|
327.3 |
|
Day 728 |
472 |
0.50 |
|
|
|
Day 738 |
421 |
0.25 |
|
340 |
|
Day 738 |
422 |
0.25 |
|
335.4 |
|
Day 738 |
430 |
0.25 |
|
346.6 |
|
Day 738 |
431 |
0.25 |
|
330.7 |
|
Day 738 |
441 |
0.50 |
|
305.5 |
|
Day 738 |
443 |
0.50 |
|
323.2 |
|
Day 738 |
444 |
0.50 |
|
336 |
|
Day 738 |
445 |
0.50 |
|
320.2 |
|
Day 738 |
449 |
0.50 |
|
273.8 |
|
Day 738 |
454 |
0.50 |
|
310.7 |
|
Day 738 |
455 |
0.50 |
|
304 |
|
Day 738 |
456 |
0.50 |
|
317.1 |
|
Day 738 |
461 |
0.50 |
|
331.5 |
|
Day 738 |
465 |
0.50 |
|
321.3 |
|
Day 738 |
469 |
0.50 |
|
330.3 |
|
Day 738 |
470 |
0.50 |
|
335.3 |
|
Day 738 |
471 |
0.50 |
|
325.3 |
|
Day 738 |
473 |
0.50 |
|
309.1 |
|
Day 738 |
474 |
0.50 |
|
304.7 |
|
Day 738 |
476 |
0.50 |
|
345.7 |
|
Day 738 |
477 |
0.50 |
|
324.7 |
|
Day 738 |
478 |
0.50 |
|
346.6 |
|
Day 738 |
479 |
0.50 |
|
357.7 |
|
Day 738 |
482 |
0.50 |
|
345.1 |
|
Day 738 |
483 |
0.50 |
|
325.2 |
|
Day 738 |
486 |
0.50 |
|
320.3 |
|
Day 738 |
492 |
0.50 |
|
308.4 |
|
Day 738 |
515 |
1.00 |
|
306.7 |
|
Day 738 |
528 |
1.00 |
|
290.7 |
|
Day 738 |
530 |
1.00 |
|
318.6 |
|
Day 738 |
531 |
1.00 |
|
314.1 |
|
Day 738 |
539 |
1.00 |
|
338.4 |
|
Day 739 |
334 |
0 |
|
321.8 |
|
Day 739 |
335 |
0 |
|
325.3 |
|
Day 739 |
351 |
0 |
|
318.2 |
|
Day 739 |
352 |
0 |
|
346.1 |
|
Day 739 |
355 |
0 |
|
327.5 |
|
Day 739 |
356 |
0 |
|
355.3 |
|
Day 739 |
357 |
0 |
|
328.1 |
|
Day 739 |
359 |
0 |
|
318.6 |
|
Day 739 |
360 |
0 |
|
304 |
|
Day 739 |
362 |
0 |
|
341.9 |
|
Day 739 |
363 |
0 |
|
322.1 |
|
Day 739 |
364 |
0 |
|
308.7 |
|
Day 739 |
365 |
0 |
|
329.8 |
|
Day 739 |
366 |
0 |
|
334.7 |
|
Day 739 |
368 |
0 |
|
361.7 |
|
Day 739 |
369 |
0 |
|
377.2 |
|
Day 739 |
370 |
0 |
|
363.7 |
|
Day 739 |
381 |
0.25 |
|
327.9 |
|
Day 739 |
382 |
0.25 |
|
279.3 |
|
Day 739 |
389 |
0.25 |
|
331.3 |
|
Day 739 |
390 |
0.25 |
|
289.6 |
|
Day 739 |
393 |
0.25 |
|
250 |
|
Day 739 |
395 |
0.25 |
|
317.1 |
|
Day 739 |
396 |
0.25 |
|
331.4 |
|
Day 739 |
399 |
0.25 |
|
320.6 |
|
Day 739 |
400 |
0.25 |
|
354.7 |
|
Day 739 |
401 |
0.25 |
|
349.2 |
|
Day 739 |
402 |
0.25 |
|
352.7 |
|
Day 739 |
403 |
0.25 |
|
309.8 |
|
Day 739 |
406 |
0.25 |
|
342.3 |
|
Day 739 |
408 |
0.25 |
|
332.1 |
|
Day 739 |
411 |
0.25 |
|
372.1 |
|
Day 739 |
413 |
0.25 |
|
331.4 |
|
Day 739 |
414 |
0.25 |
|
272.5 |
|
Day 739 |
416 |
0.25 |
|
336 |
|
Day 739 |
418 |
0.25 |
|
356.1 |
|
Day 739 |
420 |
0.25 |
|
338.4 |
|
Day 739 |
426 |
0.25 |
|
333.4 |
|
Day 739 |
427 |
0.25 |
|
357.8 |
|
Day 739 |
428 |
0.25 |
|
312 |
|
Day 740 |
321 |
0 |
|
354.8 |
|
Day 740 |
322 |
0 |
|
308.2 |
|
Day 740 |
324 |
0 |
|
303.3 |
|
Day 740 |
325 |
0 |
|
305.6 |
|
Day 740 |
326 |
0 |
|
321.8 |
|
Day 740 |
327 |
0 |
|
359.3 |
|
Day 740 |
328 |
0 |
|
302.4 |
|
Day 740 |
336 |
0 |
|
350.8 |
|
Day 740 |
337 |
0 |
|
400.9 |
|
Day 740 |
338 |
0 |
|
363.3 |
|
Day 740 |
339 |
0 |
|
341.9 |
|
Day 740 |
340 |
0 |
|
280 |
|
Day 740 |
342 |
0 |
|
353.9 |
|
Day 740 |
343 |
0 |
|
368.1 |
|
Day 740 |
344 |
0 |
|
269.3 |
|
Day 740 |
345 |
0 |
|
197.2 |
|
Day 740 |
347 |
0 |
|
323.2 |
|
Day 740 |
348 |
0 |
|
285.6 |
|
Day 740 |
350 |
0 |
|
284.6 |
|
Abbreviations: |
NA: Not Available
|