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Short-Term Individual Animal Non Neoplastic Diagnosis
Study Information:
Chemical Name: | 2,4-Decadienal |
CASRN: | ="25152-84-5" |
Study Number: | C93022B |
Exposure Route: | GAVAGE |
TDMS Number: | 9302204 |
Sex: | Female |
Strain and Species: | B6C3F1 Mice |
Female Individual Animal Non Neoplastic Diagnoses
System |
Organ |
Site |
Treatment Group |
Number Examined |
Cage Number |
Animal Number |
Days on Study |
Lesion Found |
Lesion Name |
Lesion Qualifier |
Removal Reason |
Alimentary System |
Esophagus |
|
800 MG/KG/DY |
10 |
71 |
111 |
10 |
1 |
Inflammation |
Moderate, Acute |
Dosing Accident |
Alimentary System |
Esophagus |
|
800 MG/KG/DY |
10 |
71 |
115 |
94 |
1 |
Inflammation |
Minimal, Chronic |
Terminal Sacrifice |
Alimentary System |
Esophagus |
|
100 MG/KG/DY |
1 |
65 |
85 |
8 |
1 |
Perforation |
Moderate |
Dosing Accident |
Alimentary System |
Esophagus |
|
800 MG/KG/DY |
10 |
71 |
111 |
10 |
1 |
Perforation |
Moderate |
Dosing Accident |
Alimentary System |
Liver |
|
800 MG/KG/DY |
10 |
71 |
111 |
10 |
1 |
Necrosis |
Minimal, Focal |
Dosing Accident |
Alimentary System |
Salivary Glands |
|
800 MG/KG/DY |
10 |
71 |
115 |
94 |
1 |
Inflammation |
Mild, Suppurative |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach |
800 MG/KG/DY |
10 |
71 |
111 |
10 |
1 |
Hyperkeratosis |
Moderate |
Dosing Accident |
Alimentary System |
Stomach |
Forestomach |
800 MG/KG/DY |
10 |
71 |
111 |
10 |
1 |
Inflammation |
Mild, Acute |
Dosing Accident |
Alimentary System |
Stomach |
Forestomach |
800 MG/KG/DY |
10 |
71 |
114 |
94 |
1 |
Inflammation |
Minimal, Chronic |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach |
800 MG/KG/DY |
10 |
72 |
116 |
94 |
1 |
Inflammation |
Minimal, Chronic |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach |
800 MG/KG/DY |
10 |
72 |
118 |
94 |
1 |
Inflammation |
Minimal, Chronic |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
400 MG/KG/DY |
10 |
69 |
102 |
94 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
800 MG/KG/DY |
10 |
71 |
111 |
10 |
1 |
Hyperplasia |
Moderate |
Dosing Accident |
Alimentary System |
Stomach |
Forestomach, Epithelium |
800 MG/KG/DY |
10 |
71 |
114 |
94 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
800 MG/KG/DY |
10 |
72 |
116 |
94 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
800 MG/KG/DY |
10 |
72 |
118 |
94 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Stomach |
Glandular |
800 MG/KG/DY |
10 |
71 |
114 |
94 |
1 |
Inflammation |
Mild, Acute |
Terminal Sacrifice |
Alimentary System |
Stomach |
Glandular |
800 MG/KG/DY |
10 |
71 |
114 |
94 |
1 |
Ulcer |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
Atrium |
100 MG/KG/DY |
1 |
65 |
85 |
8 |
1 |
Inflammation |
Mild, Acute |
Dosing Accident |
Endocrine System |
Parathyroid Gland |
|
800 MG/KG/DY |
10 |
72 |
119 |
94 |
1 |
Cyst |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
100 MG/KG/DY |
1 |
65 |
85 |
8 |
1 |
Necrosis |
Mild, Lymphoid |
Dosing Accident |
Musculoskeletal System |
Bone |
Femur |
800 MG/KG/DY |
10 |
71 |
111 |
10 |
1 |
Fibrous Osteodystrophy |
Mild |
Dosing Accident |
Respiratory System |
Lung |
Mediastinum |
100 MG/KG/DY |
1 |
65 |
85 |
8 |
1 |
Necrosis |
Mild |
Dosing Accident |
Respiratory System |
Lung |
Perivascular |
800 MG/KG/DY |
10 |
71 |
115 |
94 |
1 |
Inflammation |
Minimal, Chronic |
Terminal Sacrifice |
Respiratory System |
Lung |
|
800 MG/KG/DY |
10 |
71 |
111 |
10 |
1 |
Inflammation |
Mild, Acute |
Dosing Accident |
Respiratory System |
Nose |
Olfactory Epi |
400 MG/KG/DY |
10 |
69 |
102 |
94 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Respiratory System |
Nose |
Olfactory Epi |
400 MG/KG/DY |
10 |
70 |
110 |
94 |
1 |
Atrophy |
Moderate |
Terminal Sacrifice |
Respiratory System |
Nose |
Olfactory Epi |
800 MG/KG/DY |
10 |
71 |
113 |
94 |
1 |
Atrophy |
Moderate |
Terminal Sacrifice |
Respiratory System |
Nose |
Olfactory Epi |
100 MG/KG/DY |
10 |
65 |
83 |
94 |
1 |
Degeneration |
Minimal, Hydropic |
Terminal Sacrifice |
Respiratory System |
Nose |
Olfactory Epi |
200 MG/KG/DY |
10 |
67 |
91 |
94 |
1 |
Necrosis |
Moderate |
Terminal Sacrifice |
Respiratory System |
Nose |
Olfactory Epi |
200 MG/KG/DY |
10 |
67 |
92 |
94 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Respiratory System |
Nose |
Olfactory Epi |
200 MG/KG/DY |
10 |
67 |
94 |
94 |
1 |
Necrosis |
Moderate |
Terminal Sacrifice |
Respiratory System |
Nose |
Olfactory Epi |
200 MG/KG/DY |
10 |
67 |
95 |
94 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Respiratory System |
Nose |
Olfactory Epi |
200 MG/KG/DY |
10 |
68 |
96 |
94 |
1 |
Necrosis |
Moderate |
Terminal Sacrifice |
Respiratory System |
Nose |
Olfactory Epi |
200 MG/KG/DY |
10 |
68 |
99 |
94 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Respiratory System |
Nose |
Olfactory Epi |
400 MG/KG/DY |
10 |
69 |
102 |
94 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Respiratory System |
Nose |
Olfactory Epi |
400 MG/KG/DY |
10 |
69 |
105 |
94 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Respiratory System |
Nose |
Olfactory Epi |
400 MG/KG/DY |
10 |
70 |
107 |
94 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Respiratory System |
Nose |
Olfactory Epi |
400 MG/KG/DY |
10 |
70 |
109 |
94 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Respiratory System |
Nose |
Olfactory Epi |
400 MG/KG/DY |
10 |
70 |
110 |
94 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Respiratory System |
Nose |
Olfactory Epi |
800 MG/KG/DY |
10 |
71 |
113 |
94 |
1 |
Necrosis |
Moderate |
Terminal Sacrifice |
Respiratory System |
Nose |
Olfactory Epi |
800 MG/KG/DY |
10 |
72 |
116 |
94 |
1 |
Necrosis |
Moderate |
Terminal Sacrifice |
Respiratory System |
Nose |
Respirat Epith, Sinus |
800 MG/KG/DY |
10 |
71 |
113 |
94 |
1 |
Metaplasia |
Moderate, Squamous |
Terminal Sacrifice |
Respiratory System |
Nose |
Sinus |
800 MG/KG/DY |
10 |
71 |
113 |
94 |
1 |
Inflammation |
Minimal, Acute |
Terminal Sacrifice |