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Long-Term Study
Organ Weights Individual Animal
Study Information:
Chemical Name: | 2-Methylimidazole |
CASRN: | ="693-98-1" |
Study Number: | C92012B |
Study Length (Year Completed): |
(N/A) |
Exposure Route: | DOSED FEED |
TDMS Number: | 9201205 |
Sex: | Male |
Strain and Species: | F 344/N Rats |
Organ Weights Individual Animal Data |
Measurement Time |
Animal Number |
Dose Group (PPM) |
Control Code |
Final Body Weight |
Final Body Weight (g) |
Day 183 |
37 |
0 |
|
423.2 |
|
Day 183 |
38 |
0 |
|
408.9 |
|
Day 183 |
39 |
0 |
|
456.3 |
|
Day 183 |
4 |
0 |
|
364.5 |
|
Day 183 |
40 |
0 |
|
390 |
|
Day 183 |
5 |
0 |
|
393 |
|
Day 183 |
55 |
0 |
|
389 |
|
Day 183 |
56 |
0 |
|
424.5 |
|
Day 183 |
57 |
0 |
|
396.6 |
|
Day 183 |
6 |
0 |
|
411.2 |
|
Day 183 |
112 |
300 |
|
391.4 |
|
Day 183 |
113 |
300 |
|
401.6 |
|
Day 183 |
114 |
300 |
|
386.8 |
|
Day 183 |
118 |
300 |
|
385.6 |
|
Day 183 |
119 |
300 |
|
388.9 |
|
Day 183 |
120 |
300 |
|
399.8 |
|
Day 183 |
82 |
300 |
|
390.2 |
|
Day 183 |
94 |
300 |
|
382.3 |
|
Day 183 |
95 |
300 |
|
380.1 |
|
Day 183 |
96 |
300 |
|
385.9 |
|
Day 183 |
121 |
1000 |
|
422 |
|
Day 183 |
136 |
1000 |
|
388.9 |
|
Day 183 |
137 |
1000 |
|
388.4 |
|
Day 183 |
138 |
1000 |
|
398.8 |
|
Day 183 |
139 |
1000 |
|
388.6 |
|
Day 183 |
140 |
1000 |
|
441 |
|
Day 183 |
141 |
1000 |
|
373.5 |
|
Day 183 |
145 |
1000 |
|
421.6 |
|
Day 183 |
146 |
1000 |
|
347.1 |
|
Day 183 |
147 |
1000 |
|
388.3 |
|
Day 183 |
187 |
3000 |
|
381.9 |
|
Day 183 |
188 |
3000 |
|
361.6 |
|
Day 183 |
189 |
3000 |
|
363.8 |
|
Day 183 |
193 |
3000 |
|
353 |
|
Day 183 |
194 |
3000 |
|
356 |
|
Day 183 |
195 |
3000 |
|
328.2 |
|
Day 183 |
229 |
3000 |
|
363.6 |
|
Day 183 |
230 |
3000 |
|
388.3 |
|
Day 183 |
231 |
3000 |
|
350.9 |
|
Day 183 |
232 |
3000 |
|
364.1 |
|
Day 249 |
221 |
3000 |
|
|
|
Day 315 |
10 |
0 |
|
|
|
Day 392 |
162 |
1000 |
|
|
|
Day 395 |
219 |
3000 |
|
|
|
Day 439 |
163 |
1000 |
|
|
|
Day 471 |
172 |
1000 |
|
281.9 |
|
Day 491 |
220 |
3000 |
|
313.5 |
|
Day 507 |
88 |
300 |
|
277.2 |
|
Day 521 |
100 |
300 |
|
|
|
Day 538 |
164 |
1000 |
|
384.4 |
|
Day 548 |
110 |
300 |
|
294.3 |
|
Day 548 |
132 |
1000 |
|
|
|
Day 562 |
204 |
3000 |
|
291 |
|
Day 572 |
8 |
0 |
|
269.7 |
|
Day 572 |
90 |
300 |
|
|
|
Day 574 |
234 |
3000 |
|
333.1 |
|
Day 583 |
180 |
1000 |
|
315.6 |
|
Day 598 |
203 |
3000 |
|
296.2 |
|
Day 598 |
224 |
3000 |
|
260.3 |
|
Day 603 |
34 |
0 |
|
350.2 |
|
Day 605 |
75 |
300 |
|
308.3 |
|
Day 605 |
222 |
3000 |
|
305.7 |
|
Day 608 |
72 |
300 |
|
|
|
Day 618 |
233 |
3000 |
|
251.5 |
|
Day 638 |
23 |
0 |
|
281.8 |
|
Day 641 |
150 |
1000 |
|
|
|
Day 643 |
9 |
0 |
|
275.1 |
|
Day 644 |
123 |
1000 |
|
356 |
|
Day 651 |
16 |
0 |
|
322.4 |
|
Day 660 |
116 |
300 |
|
379.6 |
|
Day 668 |
2 |
0 |
|
370.5 |
|
Day 668 |
101 |
300 |
|
278.7 |
|
Day 668 |
173 |
1000 |
|
|
|
Day 673 |
156 |
1000 |
|
|
|
Day 675 |
61 |
300 |
|
306.9 |
|
Day 680 |
26 |
0 |
|
312.7 |
|
Day 687 |
183 |
3000 |
|
121.8 |
|
Day 689 |
31 |
0 |
|
283.7 |
|
Day 689 |
199 |
3000 |
|
250.9 |
|
Day 689 |
202 |
3000 |
|
323.6 |
|
Day 689 |
226 |
3000 |
|
306.3 |
|
Day 693 |
105 |
300 |
|
|
|
Day 694 |
22 |
0 |
|
298.6 |
|
Day 694 |
54 |
0 |
|
281.1 |
|
Day 694 |
168 |
1000 |
|
283.1 |
|
Day 696 |
48 |
0 |
|
307.7 |
|
Day 696 |
167 |
1000 |
|
335.5 |
|
Day 702 |
205 |
3000 |
|
266.2 |
|
Day 703 |
151 |
1000 |
|
295.2 |
|
Day 706 |
181 |
3000 |
|
276.3 |
|
Day 716 |
59 |
0 |
|
315.7 |
|
Day 717 |
166 |
1000 |
|
|
|
Day 722 |
43 |
0 |
|
315.7 |
|
Day 726 |
42 |
0 |
|
|
|
Day 729 |
11 |
0 |
|
441 |
|
Day 729 |
12 |
0 |
|
326.6 |
|
Day 729 |
17 |
0 |
|
309.4 |
|
Day 729 |
18 |
0 |
|
458.1 |
|
Day 729 |
44 |
0 |
|
414.8 |
|
Day 729 |
45 |
0 |
|
401 |
|
Day 729 |
49 |
0 |
|
441.5 |
|
Day 729 |
50 |
0 |
|
406.8 |
|
Day 729 |
51 |
0 |
|
459.9 |
|
Day 729 |
58 |
0 |
|
389.9 |
|
Day 729 |
60 |
0 |
|
432.4 |
|
Day 729 |
62 |
300 |
|
|
|
Day 729 |
67 |
300 |
|
385 |
|
Day 729 |
68 |
300 |
|
431.1 |
|
Day 729 |
69 |
300 |
|
436.5 |
|
Day 729 |
85 |
300 |
|
435.5 |
|
Day 729 |
86 |
300 |
|
427.6 |
|
Day 729 |
87 |
300 |
|
399.4 |
|
Day 729 |
89 |
300 |
|
396.4 |
|
Day 729 |
133 |
1000 |
|
401.1 |
|
Day 729 |
134 |
1000 |
|
411.1 |
|
Day 729 |
135 |
1000 |
|
321.2 |
|
Day 729 |
174 |
1000 |
|
406.9 |
|
Day 729 |
196 |
3000 |
|
408.9 |
|
Day 729 |
197 |
3000 |
|
380.7 |
|
Day 729 |
198 |
3000 |
|
405.7 |
|
Day 729 |
200 |
3000 |
|
379.6 |
|
Day 729 |
201 |
3000 |
|
371.6 |
|
Day 729 |
206 |
3000 |
|
393 |
|
Day 729 |
207 |
3000 |
|
386.7 |
|
Day 729 |
227 |
3000 |
|
392 |
|
Day 729 |
228 |
3000 |
|
385.1 |
|
Day 729 |
235 |
3000 |
|
335.7 |
|
Day 729 |
236 |
3000 |
|
361.6 |
|
Day 729 |
237 |
3000 |
|
346.9 |
|
Day 729 |
238 |
3000 |
|
391.9 |
|
Day 729 |
239 |
3000 |
|
275.3 |
|
Day 729 |
240 |
3000 |
|
328.4 |
|
Day 730 |
13 |
0 |
|
412.7 |
|
Day 730 |
14 |
0 |
|
429 |
|
Day 730 |
15 |
0 |
|
414.9 |
|
Day 730 |
19 |
0 |
|
450.5 |
|
Day 730 |
20 |
0 |
|
422.6 |
|
Day 730 |
21 |
0 |
|
465.9 |
|
Day 730 |
25 |
0 |
|
424.3 |
|
Day 730 |
27 |
0 |
|
427.7 |
|
Day 730 |
32 |
0 |
|
427.6 |
|
Day 730 |
33 |
0 |
|
405.1 |
|
Day 730 |
35 |
0 |
|
400.4 |
|
Day 730 |
36 |
0 |
|
406.1 |
|
Day 730 |
102 |
300 |
|
363.9 |
|
Day 730 |
106 |
300 |
|
381.9 |
|
Day 730 |
107 |
300 |
|
446.4 |
|
Day 730 |
108 |
300 |
|
445.9 |
|
Day 730 |
64 |
300 |
|
392.7 |
|
Day 730 |
65 |
300 |
|
432 |
|
Day 730 |
66 |
300 |
|
442.5 |
|
Day 730 |
97 |
300 |
|
468.3 |
|
Day 730 |
98 |
300 |
|
424.6 |
|
Day 730 |
99 |
300 |
|
420.7 |
|
Day 730 |
154 |
1000 |
|
340.6 |
|
Day 730 |
155 |
1000 |
|
410.8 |
|
Day 730 |
160 |
1000 |
|
379.5 |
|
Day 730 |
161 |
1000 |
|
392.5 |
|
Day 730 |
165 |
1000 |
|
401.2 |
|
Day 730 |
169 |
1000 |
|
417.9 |
|
Day 730 |
170 |
1000 |
|
407.1 |
|
Day 730 |
171 |
1000 |
|
433.1 |
|
Day 730 |
184 |
3000 |
|
286.7 |
|
Day 730 |
185 |
3000 |
|
265.4 |
|
Day 730 |
186 |
3000 |
|
382.9 |
|
Day 730 |
190 |
3000 |
|
417.1 |
|
Day 730 |
191 |
3000 |
|
371.7 |
|
Day 730 |
192 |
3000 |
|
415.7 |
|
Day 730 |
208 |
3000 |
|
388.5 |
|
Day 730 |
209 |
3000 |
|
433.3 |
|
Day 730 |
210 |
3000 |
|
419.6 |
|
Day 730 |
211 |
3000 |
|
376.8 |
|
Day 730 |
212 |
3000 |
|
386.3 |
|
Day 730 |
213 |
3000 |
|
407.2 |
|
Day 730 |
214 |
3000 |
|
419 |
|
Day 730 |
215 |
3000 |
|
395.7 |
|
Day 730 |
216 |
3000 |
|
355.4 |
|
Day 730 |
217 |
3000 |
|
400.3 |
|
Day 730 |
218 |
3000 |
|
297.1 |
|
Day 731 |
1 |
0 |
|
406.1 |
|
Day 731 |
24 |
0 |
|
372.1 |
|
Day 731 |
3 |
0 |
|
444.3 |
|
Day 731 |
41 |
0 |
|
438.3 |
|
Day 731 |
52 |
0 |
|
374.1 |
|
Day 731 |
103 |
300 |
|
433.6 |
|
Day 731 |
104 |
300 |
|
437.1 |
|
Day 731 |
115 |
300 |
|
411.1 |
|
Day 731 |
117 |
300 |
|
409.9 |
|
Day 731 |
63 |
300 |
|
406.2 |
|
Day 731 |
73 |
300 |
|
435.5 |
|
Day 731 |
74 |
300 |
|
414 |
|
Day 731 |
76 |
300 |
|
390.5 |
|
Day 731 |
77 |
300 |
|
447.8 |
|
Day 731 |
78 |
300 |
|
418.6 |
|
Day 731 |
79 |
300 |
|
418.9 |
|
Day 731 |
80 |
300 |
|
423.1 |
|
Day 731 |
81 |
300 |
|
429.5 |
|
Day 731 |
83 |
300 |
|
424.3 |
|
Day 731 |
84 |
300 |
|
407.8 |
|
Day 731 |
142 |
1000 |
|
442.6 |
|
Day 731 |
143 |
1000 |
|
398.3 |
|
Day 731 |
144 |
1000 |
|
344.4 |
|
Day 731 |
148 |
1000 |
|
400.5 |
|
Day 731 |
149 |
1000 |
|
414.7 |
|
Day 731 |
152 |
1000 |
|
333.6 |
|
Day 731 |
153 |
1000 |
|
|
|
Day 731 |
182 |
3000 |
|
275.5 |
|
Day 731 |
223 |
3000 |
|
302.8 |
|
Day 731 |
225 |
3000 |
|
404 |
|
Day 734 |
28 |
0 |
|
409.7 |
|
Day 734 |
29 |
0 |
|
371.1 |
|
Day 734 |
30 |
0 |
|
421 |
|
Day 734 |
46 |
0 |
|
420.2 |
|
Day 734 |
47 |
0 |
|
405.3 |
|
Day 734 |
53 |
0 |
|
381 |
|
Day 734 |
7 |
0 |
|
379.2 |
|
Day 734 |
109 |
300 |
|
395.2 |
|
Day 734 |
111 |
300 |
|
373.1 |
|
Day 734 |
70 |
300 |
|
426 |
|
Day 734 |
71 |
300 |
|
386 |
|
Day 734 |
91 |
300 |
|
432.9 |
|
Day 734 |
92 |
300 |
|
447.4 |
|
Day 734 |
93 |
300 |
|
385.8 |
|
Day 734 |
122 |
1000 |
|
411.7 |
|
Day 734 |
124 |
1000 |
|
422.5 |
|
Day 734 |
125 |
1000 |
|
422.8 |
|
Day 734 |
126 |
1000 |
|
404.8 |
|
Day 734 |
127 |
1000 |
|
403.8 |
|
Day 734 |
128 |
1000 |
|
433.9 |
|
Day 734 |
129 |
1000 |
|
395.2 |
|
Day 734 |
130 |
1000 |
|
422.1 |
|
Day 734 |
131 |
1000 |
|
421.9 |
|
Day 734 |
157 |
1000 |
|
391.7 |
|
Day 734 |
158 |
1000 |
|
423 |
|
Day 734 |
159 |
1000 |
|
429.2 |
|
Day 734 |
175 |
1000 |
|
428.1 |
|
Day 734 |
176 |
1000 |
|
432.4 |
|
Day 734 |
177 |
1000 |
|
412 |
|
Day 734 |
178 |
1000 |
|
427.4 |
|
Day 734 |
179 |
1000 |
|
427.9 |
|
Abbreviations: |
NA: Not Available
|