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Short-Term Individual Animal Neoplastic Diagnosis
Study Information:
Chemical Name: | 3'-Azido-3'-deoxythymidine (AIDS) |
CASRN: | ="30516-87-1" |
Study Number: | C20310C |
Exposure Route: | GAVAGE |
TDMS Number: | 2031001 |
Sex: | Female |
Strain and Species: | C3B6F1-+/Trp53(tm1Brd) Mice |
Female Individual Animal Neoplastic Diagnoses
System |
Organ |
Site |
Treatment Group |
Number Examined |
Cage Number |
Animal Number |
Days on Study |
Lesion Found |
Lesion Name |
Lesion Qualifier |
Removal Reason |
Alimentary System |
Gallbladder |
|
Vehicle Control |
27 |
879 |
443 |
206 |
1 |
Lymphoma Malignant |
|
Moribund Sacrifice |
Alimentary System |
Gallbladder |
|
120 |
26 |
888 |
502 |
229 |
1 |
Sarcoma |
|
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum |
40 |
27 |
582 |
451 |
226 |
1 |
Histiocytic Sarcoma |
|
Moribund Sacrifice |
Alimentary System |
Intestine Large |
Cecum |
80 |
27 |
604 |
407 |
336 |
1 |
Lymphoma Malignant |
|
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum |
120 |
26 |
785 |
287 |
227 |
1 |
Lymphoma Malignant |
|
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum |
120 |
27 |
444 |
329 |
339 |
1 |
Lymphoma Malignant |
|
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum |
Vehicle Control |
27 |
796 |
283 |
226 |
1 |
Polyp |
|
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon |
40 |
27 |
582 |
451 |
226 |
1 |
Histiocytic Sarcoma |
|
Moribund Sacrifice |
Alimentary System |
Intestine Large |
Rectum |
120 |
26 |
785 |
287 |
227 |
1 |
Lymphoma Malignant |
|
Terminal Sacrifice |
Alimentary System |
Intestine Small |
Ileum |
40 |
27 |
582 |
451 |
226 |
1 |
Histiocytic Sarcoma |
|
Moribund Sacrifice |
Alimentary System |
Intestine Small |
Ileum |
120 |
26 |
785 |
287 |
227 |
1 |
Lymphoma Malignant |
|
Terminal Sacrifice |
Alimentary System |
Intestine Small |
Jejunum |
120 |
27 |
444 |
329 |
339 |
1 |
Lymphoma Malignant |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
40 |
27 |
582 |
451 |
226 |
1 |
Histiocytic Sarcoma |
|
Moribund Sacrifice |
Alimentary System |
Liver |
|
120 |
27 |
667 |
674 |
292 |
1 |
Histiocytic Sarcoma |
|
Natural Death |
Alimentary System |
Liver |
|
40 |
26 |
2507 |
584 |
334 |
1 |
Leukemia Granulocytic |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
27 |
879 |
443 |
206 |
1 |
Lymphoma Malignant |
|
Moribund Sacrifice |
Alimentary System |
Liver |
|
120 |
27 |
477 |
453 |
255 |
1 |
Lymphoma Malignant |
|
Natural Death |
Alimentary System |
Liver |
|
Vehicle Control |
26 |
613 |
209 |
198 |
1 |
Sarcoma |
|
Moribund Sacrifice |
Alimentary System |
Liver |
|
120 |
26 |
888 |
502 |
229 |
1 |
Sarcoma |
|
Terminal Sacrifice |
Alimentary System |
Pancreas |
|
40 |
27 |
582 |
451 |
226 |
1 |
Histiocytic Sarcoma |
|
Moribund Sacrifice |
Alimentary System |
Pancreas |
|
Vehicle Control |
27 |
879 |
443 |
206 |
1 |
Lymphoma Malignant |
|
Moribund Sacrifice |
Alimentary System |
Stomach |
Forestomach |
40 |
27 |
679 |
545 |
336 |
1 |
Squamous Cell Papilloma |
|
Terminal Sacrifice |
Alimentary System |
Stomach |
Glandular |
Vehicle Control |
27 |
879 |
443 |
206 |
1 |
Lymphoma Malignant |
|
Moribund Sacrifice |
Cardiovascular System |
Heart |
|
40 |
26 |
2507 |
584 |
334 |
1 |
Leukemia Granulocytic |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
|
80 |
27 |
469 |
340 |
336 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
|
Vehicle Control |
27 |
879 |
443 |
206 |
1 |
Lymphoma Malignant |
|
Moribund Sacrifice |
Endocrine System |
Adrenal Medulla |
|
Vehicle Control |
27 |
879 |
443 |
206 |
1 |
Lymphoma Malignant |
|
Moribund Sacrifice |
Endocrine System |
Pituitary Gland |
|
120 |
27 |
667 |
674 |
292 |
1 |
Histiocytic Sarcoma |
|
Natural Death |
Endocrine System |
Pituitary Gland |
|
Vehicle Control |
27 |
879 |
443 |
206 |
1 |
Lymphoma Malignant |
|
Moribund Sacrifice |
General Body System |
Tissue NOS |
Thoracic |
40 |
1 |
569 |
445 |
296 |
1 |
Osteosarcoma |
|
Natural Death |
Genital System |
Ovary |
|
40 |
27 |
582 |
451 |
226 |
1 |
Histiocytic Sarcoma |
|
Moribund Sacrifice |
Genital System |
Ovary |
|
Vehicle Control |
26 |
547 |
376 |
334 |
1 |
Luteoma |
|
Terminal Sacrifice |
Genital System |
Ovary |
|
Vehicle Control |
27 |
879 |
443 |
206 |
1 |
Lymphoma Malignant |
|
Moribund Sacrifice |
Genital System |
Ovary |
|
Vehicle Control |
26 |
2454 |
572 |
335 |
1 |
Teratoma Malignant |
|
Terminal Sacrifice |
Genital System |
Ovary |
|
Vehicle Control |
26 |
2649 |
608 |
273 |
1 |
Yolk Sac Carcinoma |
|
Natural Death |
Genital System |
Uterus |
Endometrium |
Vehicle Control |
27 |
755 |
251 |
225 |
1 |
Polyp Stromal |
|
Terminal Sacrifice |
Genital System |
Uterus |
Endometrium |
40 |
27 |
490 |
364 |
333 |
1 |
Polyp Stromal |
|
Terminal Sacrifice |
Genital System |
Uterus |
|
40 |
27 |
582 |
451 |
226 |
1 |
Histiocytic Sarcoma |
|
Moribund Sacrifice |
Genital System |
Uterus |
|
Vehicle Control |
27 |
879 |
443 |
206 |
1 |
Lymphoma Malignant |
|
Moribund Sacrifice |
Genital System |
Uterus |
|
Vehicle Control |
26 |
2453 |
571 |
335 |
1 |
Polyp Stromal |
|
Terminal Sacrifice |
Genital System |
Uterus |
|
40 |
26 |
2556 |
606 |
332 |
1 |
Polyp Stromal |
|
Terminal Sacrifice |
Genital System |
Uterus |
|
40 |
26 |
2557 |
607 |
332 |
1 |
Sarcoma Stromal |
|
Terminal Sacrifice |
Genital System |
Vagina |
|
Vehicle Control |
27 |
879 |
443 |
206 |
1 |
Lymphoma Malignant |
|
Moribund Sacrifice |
Hematopoietic System |
Bone Marrow |
|
40 |
27 |
582 |
451 |
226 |
1 |
Histiocytic Sarcoma |
|
Moribund Sacrifice |
Hematopoietic System |
Bone Marrow |
|
120 |
27 |
667 |
674 |
292 |
1 |
Histiocytic Sarcoma |
|
Natural Death |
Hematopoietic System |
Bone Marrow |
|
40 |
26 |
2507 |
584 |
334 |
1 |
Leukemia Granulocytic |
|
Terminal Sacrifice |
Hematopoietic System |
Bone Marrow |
|
Vehicle Control |
27 |
879 |
443 |
206 |
1 |
Lymphoma Malignant |
|
Moribund Sacrifice |
Hematopoietic System |
Bone Marrow |
|
Vehicle Control |
26 |
613 |
209 |
198 |
1 |
Sarcoma |
|
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Axillary |
Vehicle Control |
27 |
879 |
443 |
206 |
1 |
Lymphoma Malignant |
|
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Axillary |
120 |
27 |
477 |
453 |
255 |
1 |
Lymphoma Malignant |
|
Natural Death |
Hematopoietic System |
Lymph Node |
Lumbar |
40 |
27 |
582 |
451 |
226 |
1 |
Histiocytic Sarcoma |
|
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Lumbar |
40 |
26 |
2507 |
584 |
334 |
1 |
Leukemia Granulocytic |
|
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Lumbar |
Vehicle Control |
27 |
879 |
443 |
206 |
1 |
Lymphoma Malignant |
|
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Lumbar |
120 |
27 |
477 |
453 |
255 |
1 |
Lymphoma Malignant |
|
Natural Death |
Hematopoietic System |
Lymph Node |
Lumbar |
120 |
26 |
785 |
287 |
227 |
1 |
Lymphoma Malignant |
|
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mandibular |
40 |
27 |
582 |
451 |
226 |
1 |
Histiocytic Sarcoma |
|
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Mandibular |
40 |
26 |
2507 |
584 |
334 |
1 |
Leukemia Granulocytic |
|
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mandibular |
Vehicle Control |
27 |
879 |
443 |
206 |
1 |
Lymphoma Malignant |
|
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Mandibular |
80 |
27 |
604 |
407 |
336 |
1 |
Lymphoma Malignant |
|
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mandibular |
120 |
27 |
477 |
453 |
255 |
1 |
Lymphoma Malignant |
|
Natural Death |
Hematopoietic System |
Lymph Node |
Mandibular |
Vehicle Control |
26 |
613 |
209 |
198 |
1 |
Sarcoma |
|
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
40 |
26 |
2507 |
584 |
334 |
1 |
Leukemia Granulocytic |
|
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
120 |
26 |
785 |
287 |
227 |
1 |
Lymphoma Malignant |
|
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
40 |
27 |
582 |
451 |
226 |
1 |
Histiocytic Sarcoma |
|
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
120 |
27 |
667 |
674 |
292 |
1 |
Histiocytic Sarcoma |
|
Natural Death |
Hematopoietic System |
Lymph Node |
Mesenteric |
40 |
26 |
2507 |
584 |
334 |
1 |
Leukemia Granulocytic |
|
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
Vehicle Control |
27 |
879 |
443 |
206 |
1 |
Lymphoma Malignant |
|
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
80 |
27 |
604 |
407 |
336 |
1 |
Lymphoma Malignant |
|
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
120 |
27 |
477 |
453 |
255 |
1 |
Lymphoma Malignant |
|
Natural Death |
Hematopoietic System |
Lymph Node |
Mesenteric |
120 |
26 |
785 |
287 |
227 |
1 |
Lymphoma Malignant |
|
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
120 |
27 |
444 |
329 |
339 |
1 |
Lymphoma Malignant |
|
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
Vehicle Control |
26 |
613 |
209 |
198 |
1 |
Sarcoma |
|
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
120 |
26 |
888 |
502 |
229 |
1 |
Sarcoma |
Metastatic |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Pancreatic |
120 |
27 |
477 |
453 |
255 |
1 |
Lymphoma Malignant |
|
Natural Death |
Hematopoietic System |
Lymph Node |
Renal |
120 |
27 |
667 |
674 |
292 |
1 |
Histiocytic Sarcoma |
|
Natural Death |
Hematopoietic System |
Lymph Node |
Renal |
40 |
26 |
2507 |
584 |
334 |
1 |
Leukemia Granulocytic |
|
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Renal |
Vehicle Control |
27 |
879 |
443 |
206 |
1 |
Lymphoma Malignant |
|
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Renal |
120 |
27 |
477 |
453 |
255 |
1 |
Lymphoma Malignant |
|
Natural Death |
Hematopoietic System |
Spleen |
|
40 |
27 |
582 |
451 |
226 |
1 |
Histiocytic Sarcoma |
|
Moribund Sacrifice |
Hematopoietic System |
Spleen |
|
120 |
27 |
667 |
674 |
292 |
1 |
Histiocytic Sarcoma |
|
Natural Death |
Hematopoietic System |
Spleen |
|
40 |
26 |
2507 |
584 |
334 |
1 |
Leukemia Granulocytic |
|
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
27 |
879 |
443 |
206 |
1 |
Lymphoma Malignant |
|
Moribund Sacrifice |
Hematopoietic System |
Spleen |
|
80 |
27 |
604 |
407 |
336 |
1 |
Lymphoma Malignant |
|
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
120 |
27 |
477 |
453 |
255 |
1 |
Lymphoma Malignant |
|
Natural Death |
Hematopoietic System |
Spleen |
|
120 |
26 |
785 |
287 |
227 |
1 |
Lymphoma Malignant |
|
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
120 |
27 |
444 |
329 |
339 |
1 |
Lymphoma Malignant |
|
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
120 |
27 |
526 |
369 |
335 |
1 |
Lymphoma Malignant |
|
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
26 |
613 |
209 |
198 |
1 |
Sarcoma |
|
Moribund Sacrifice |
Hematopoietic System |
Spleen |
|
120 |
26 |
888 |
502 |
229 |
1 |
Sarcoma |
Metastatic |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
40 |
27 |
582 |
451 |
226 |
1 |
Histiocytic Sarcoma |
|
Moribund Sacrifice |
Hematopoietic System |
Thymus |
|
120 |
27 |
667 |
674 |
292 |
1 |
Histiocytic Sarcoma |
|
Natural Death |
Hematopoietic System |
Thymus |
|
Vehicle Control |
27 |
879 |
443 |
206 |
1 |
Lymphoma Malignant |
|
Moribund Sacrifice |
Hematopoietic System |
Thymus |
|
80 |
27 |
604 |
407 |
336 |
1 |
Lymphoma Malignant |
|
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
120 |
27 |
477 |
453 |
255 |
1 |
Lymphoma Malignant |
|
Natural Death |
Hematopoietic System |
Thymus |
|
120 |
26 |
785 |
287 |
227 |
1 |
Lymphoma Malignant |
|
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
120 |
27 |
526 |
369 |
335 |
1 |
Lymphoma Malignant |
|
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
27 |
776 |
275 |
230 |
1 |
Adenocarcinoma |
|
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
80 |
27 |
869 |
609 |
312 |
1 |
Adenocarcinoma |
|
Moribund Sacrifice |
Integumentary System |
Mammary Gland |
|
80 |
27 |
688 |
436 |
335 |
1 |
Adenocarcinoma |
|
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
120 |
27 |
445 |
311 |
332 |
1 |
Adenocarcinoma |
|
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
26 |
2621 |
620 |
334 |
1 |
Adenoma |
|
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
27 |
879 |
443 |
206 |
1 |
Lymphoma Malignant |
|
Moribund Sacrifice |
Integumentary System |
Skin |
|
120 |
26 |
767 |
264 |
230 |
1 |
Basal Cell Carcinoma |
|
Terminal Sacrifice |
Integumentary System |
Skin |
|
120 |
27 |
443 |
449 |
307 |
1 |
Fibrosarcoma |
|
Moribund Sacrifice |
Integumentary System |
Skin |
|
80 |
27 |
580 |
385 |
334 |
1 |
Squamous Cell Carcinoma |
|
Terminal Sacrifice |
Musculoskeletal System |
Bone |
Cranium |
120 |
27 |
669 |
527 |
335 |
1 |
Osteoma |
|
Terminal Sacrifice |
Musculoskeletal System |
Bone |
Femur |
Vehicle Control |
26 |
839 |
552 |
283 |
1 |
Osteosarcoma |
|
Moribund Sacrifice |
Musculoskeletal System |
Bone |
Femur |
80 |
27 |
412 |
297 |
334 |
1 |
Osteosarcoma |
|
Terminal Sacrifice |
Musculoskeletal System |
Bone |
Femur |
80 |
27 |
413 |
318 |
337 |
1 |
Osteosarcoma |
|
Terminal Sacrifice |
Musculoskeletal System |
Bone |
Femur |
120 |
27 |
631 |
448 |
301 |
1 |
Osteosarcoma |
|
Natural Death |
Musculoskeletal System |
Bone |
Rib |
40 |
27 |
570 |
430 |
335 |
1 |
Osteosarcoma |
|
Terminal Sacrifice |
Musculoskeletal System |
Skeletal Muscle |
Intercostal |
Vehicle Control |
26 |
546 |
446 |
305 |
1 |
Mesothelioma Malignant |
|
Natural Death |
Nervous System |
Brain |
Brain Stem |
40 |
26 |
2696 |
610 |
274 |
1 |
Astrocytoma Malignant |
|
Moribund Sacrifice |
Nervous System |
Brain |
Cerebellum |
40 |
26 |
2696 |
610 |
274 |
1 |
Astrocytoma Malignant |
|
Moribund Sacrifice |
Nervous System |
Brain |
Cerebrum |
Vehicle Control |
26 |
613 |
209 |
198 |
1 |
Sarcoma |
|
Moribund Sacrifice |
Respiratory System |
Lung |
Mediastinum |
Vehicle Control |
26 |
613 |
209 |
198 |
1 |
Sarcoma |
|
Moribund Sacrifice |
Respiratory System |
Lung |
|
Vehicle Control |
27 |
776 |
275 |
230 |
1 |
Adenocarcinoma |
Metastatic |
Terminal Sacrifice |
Respiratory System |
Lung |
|
40 |
27 |
433 |
302 |
333 |
1 |
Alveolar/Bronchiolar Adenoma |
|
Terminal Sacrifice |
Respiratory System |
Lung |
|
120 |
26 |
767 |
264 |
230 |
1 |
Basal Cell Carcinoma |
Metastatic |
Terminal Sacrifice |
Respiratory System |
Lung |
|
40 |
27 |
582 |
451 |
226 |
1 |
Histiocytic Sarcoma |
|
Moribund Sacrifice |
Respiratory System |
Lung |
|
120 |
27 |
667 |
674 |
292 |
1 |
Histiocytic Sarcoma |
|
Natural Death |
Respiratory System |
Lung |
|
40 |
26 |
2507 |
584 |
334 |
1 |
Leukemia Granulocytic |
|
Terminal Sacrifice |
Respiratory System |
Lung |
|
Vehicle Control |
27 |
879 |
443 |
206 |
1 |
Lymphoma Malignant |
|
Moribund Sacrifice |
Respiratory System |
Lung |
|
80 |
27 |
604 |
407 |
336 |
1 |
Lymphoma Malignant |
|
Terminal Sacrifice |
Respiratory System |
Lung |
|
120 |
27 |
477 |
453 |
255 |
1 |
Lymphoma Malignant |
|
Natural Death |
Respiratory System |
Lung |
|
Vehicle Control |
26 |
546 |
446 |
305 |
1 |
Mesothelioma Malignant |
|
Natural Death |
Respiratory System |
Lung |
|
120 |
27 |
631 |
448 |
301 |
1 |
Osteosarcoma |
Metastatic |
Natural Death |
Respiratory System |
Lung |
|
Vehicle Control |
26 |
2649 |
608 |
273 |
1 |
Yolk Sac Carcinoma |
Metastatic |
Natural Death |
Respiratory System |
Nose |
|
80 |
27 |
604 |
407 |
336 |
1 |
Osteosarcoma |
|
Terminal Sacrifice |
Respiratory System |
Nose |
|
Vehicle Control |
26 |
613 |
209 |
198 |
1 |
Sarcoma |
|
Moribund Sacrifice |
Special Senses System |
Harderian Gland |
|
80 |
27 |
414 |
319 |
337 |
1 |
Adenoma |
|
Terminal Sacrifice |
Special Senses System |
Harderian Gland |
|
40 |
26 |
2507 |
584 |
334 |
1 |
Leukemia Granulocytic |
|
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
40 |
27 |
848 |
548 |
333 |
1 |
Adenoma |
|
Terminal Sacrifice |
Urinary System |
Kidney |
|
120 |
27 |
667 |
674 |
292 |
1 |
Histiocytic Sarcoma |
|
Natural Death |
Urinary System |
Kidney |
|
40 |
26 |
2507 |
584 |
334 |
1 |
Leukemia Granulocytic |
|
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
27 |
879 |
443 |
206 |
1 |
Lymphoma Malignant |
|
Moribund Sacrifice |
Urinary System |
Kidney |
|
120 |
27 |
477 |
453 |
255 |
1 |
Lymphoma Malignant |
|
Natural Death |
Urinary System |
Urinary Bladder |
|
40 |
26 |
2507 |
584 |
334 |
1 |
Leukemia Granulocytic |
|
Terminal Sacrifice |
Urinary System |
Urinary Bladder |
|
Vehicle Control |
27 |
879 |
443 |
206 |
1 |
Lymphoma Malignant |
|
Moribund Sacrifice |