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Long-Term Study
Organ Weights Individual Animal
Study Information:
Chemical Name: | 3,3'-Dimethoxybenzidine dihydrochloride |
CASRN: | ="20325-40-0" |
Study Number: | C99989 |
Study Length (Year Completed): |
(N/A) |
Exposure Route: | DOSED WATER |
TDMS Number: | 0517201 |
Sex: | Male |
Strain and Species: | F 344/N Rats |
Organ Weights Individual Animal Data |
Measurement Time |
Animal Number |
Dose Group () |
Control Code |
Final Body Weight (g) |
Day 73 |
42 |
0 |
|
214.9 |
Day 262 |
154 |
80 |
|
360.4 |
Day 267 |
390 |
330 |
|
291.7 |
Day 275 |
1 |
0 |
|
352.8 |
Day 275 |
10 |
0 |
|
393.2 |
Day 275 |
2 |
0 |
|
410.2 |
Day 275 |
3 |
0 |
|
372.3 |
Day 275 |
4 |
0 |
|
416.6 |
Day 275 |
5 |
0 |
|
406.2 |
Day 275 |
6 |
0 |
|
378.1 |
Day 275 |
7 |
0 |
|
427.1 |
Day 275 |
8 |
0 |
|
369.6 |
Day 275 |
9 |
0 |
|
373.9 |
Day 275 |
381 |
330 |
|
387.6 |
Day 275 |
382 |
330 |
|
408.3 |
Day 275 |
383 |
330 |
|
404.8 |
Day 275 |
384 |
330 |
|
372.8 |
Day 275 |
385 |
330 |
|
379.6 |
Day 275 |
386 |
330 |
|
364.8 |
Day 275 |
387 |
330 |
|
313.1 |
Day 275 |
388 |
330 |
|
364.8 |
Day 275 |
389 |
330 |
|
363.7 |
Day 275 |
391 |
330 |
|
370 |
Day 284 |
275 |
170 |
|
372.4 |
Day 284 |
418 |
330 |
|
388.4 |
Day 304 |
235 |
170 |
|
403.1 |
Day 304 |
447 |
330 |
|
410.1 |
Day 332 |
431 |
330 |
|
310.9 |
Day 333 |
291 |
170 |
|
350.8 |
Day 337 |
449 |
330 |
|
289 |
Day 339 |
246 |
170 |
|
425.5 |
Day 339 |
409 |
330 |
|
366.6 |
Day 344 |
396 |
330 |
|
393.6 |
Day 353 |
141 |
80 |
|
367.7 |
Day 354 |
175 |
80 |
|
383.5 |
Day 358 |
304 |
170 |
|
455.6 |
Day 391 |
232 |
170 |
|
383.4 |
Day 391 |
248 |
170 |
|
263.5 |
Day 401 |
392 |
330 |
|
485.5 |
Day 401 |
450 |
330 |
|
328.5 |
Day 402 |
421 |
330 |
|
255.1 |
Day 408 |
259 |
170 |
|
401.4 |
Day 414 |
434 |
330 |
|
349.3 |
Day 417 |
241 |
170 |
|
343.6 |
Day 419 |
415 |
330 |
|
239.6 |
Day 420 |
254 |
170 |
|
281.5 |
Day 423 |
394 |
330 |
|
319.5 |
Day 423 |
402 |
330 |
|
310.4 |
Day 423 |
438 |
330 |
|
318.8 |
Day 424 |
262 |
170 |
|
321.1 |
Day 424 |
292 |
170 |
|
403.5 |
Day 424 |
441 |
330 |
|
351.9 |
Day 425 |
446 |
330 |
|
408.6 |
Day 437 |
283 |
170 |
|
335.3 |
Day 441 |
397 |
330 |
|
259.9 |
Day 445 |
426 |
330 |
|
245.1 |
Day 452 |
15 |
0 |
|
339.6 |
Day 458 |
305 |
170 |
|
228 |
Day 467 |
264 |
170 |
|
233.6 |
Day 472 |
243 |
170 |
|
374.2 |
Day 472 |
287 |
170 |
|
341.6 |
Day 476 |
249 |
170 |
|
267.7 |
Day 476 |
437 |
330 |
|
286.6 |
Day 477 |
443 |
330 |
|
336.1 |
Day 478 |
399 |
330 |
|
311.4 |
Day 480 |
143 |
80 |
|
302.8 |
Day 480 |
161 |
80 |
|
284.7 |
Day 483 |
148 |
80 |
|
368.7 |
Day 483 |
256 |
170 |
|
317.2 |
Day 483 |
260 |
170 |
|
383 |
Day 483 |
286 |
170 |
|
300.5 |
Day 483 |
401 |
330 |
|
348 |
Day 483 |
425 |
330 |
|
313.6 |
Day 483 |
445 |
330 |
|
368.3 |
Day 485 |
164 |
80 |
|
407.2 |
Day 485 |
238 |
170 |
|
303.2 |
Day 485 |
266 |
170 |
|
376.4 |
Day 485 |
296 |
170 |
|
349.6 |
Day 485 |
303 |
170 |
|
308.8 |
Day 485 |
400 |
330 |
|
376 |
Day 485 |
440 |
330 |
|
323.8 |
Day 486 |
277 |
170 |
|
334.2 |
Day 486 |
278 |
170 |
|
391.1 |
Day 486 |
393 |
330 |
|
336.6 |
Day 486 |
403 |
330 |
|
359.4 |
Day 490 |
395 |
330 |
|
314.1 |
Day 505 |
16 |
0 |
|
287.5 |
Day 506 |
300 |
170 |
|
248.2 |
Day 506 |
444 |
330 |
|
228.3 |
Day 508 |
288 |
170 |
|
326.6 |
Day 511 |
416 |
330 |
|
318.3 |
Day 512 |
433 |
330 |
|
305.2 |
Day 514 |
294 |
170 |
|
284.4 |
Day 515 |
165 |
80 |
|
322 |
Day 521 |
442 |
330 |
|
304.9 |
Day 525 |
233 |
170 |
|
365.9 |
Day 525 |
423 |
330 |
|
242.2 |
Day 526 |
269 |
170 |
|
302.7 |
Day 527 |
430 |
330 |
|
266.6 |
Day 529 |
14 |
0 |
|
564.3 |
Day 531 |
13 |
0 |
|
385.9 |
Day 531 |
234 |
170 |
|
345.7 |
Day 533 |
301 |
170 |
|
349.6 |
Day 534 |
429 |
330 |
|
288.8 |
Day 535 |
289 |
170 |
|
293.7 |
Day 536 |
255 |
170 |
|
239.3 |
Day 536 |
436 |
330 |
|
439.6 |
Day 537 |
398 |
330 |
|
360.4 |
Day 538 |
162 |
80 |
|
341.5 |
Day 538 |
279 |
170 |
|
234.6 |
Day 539 |
251 |
170 |
|
331.7 |
Day 541 |
247 |
170 |
|
489.6 |
Day 541 |
448 |
330 |
|
330.9 |
Day 542 |
407 |
330 |
|
301.9 |
Day 542 |
419 |
330 |
|
257.1 |
Day 546 |
151 |
80 |
|
397.9 |
Day 546 |
263 |
170 |
|
274 |
Day 546 |
268 |
170 |
|
224 |
Day 546 |
285 |
170 |
|
309.6 |
Day 546 |
406 |
330 |
|
316 |
Day 546 |
428 |
330 |
|
334.9 |
Day 550 |
404 |
330 |
|
381.5 |
Day 550 |
411 |
330 |
|
298.8 |
Day 550 |
413 |
330 |
|
297.7 |
Day 551 |
424 |
330 |
|
346.1 |
Day 552 |
144 |
80 |
|
314.4 |
Day 553 |
267 |
170 |
|
299.6 |
Day 555 |
252 |
170 |
|
319.1 |
Day 556 |
168 |
80 |
|
417.3 |
Day 556 |
171 |
80 |
|
439.4 |
Day 556 |
236 |
170 |
|
331.2 |
Day 556 |
272 |
170 |
|
454.4 |
Day 556 |
290 |
170 |
|
462.8 |
Day 556 |
297 |
170 |
|
380.1 |
Day 557 |
281 |
170 |
|
337.2 |
Day 558 |
178 |
80 |
|
256.9 |
Day 560 |
242 |
170 |
|
362.1 |
Day 560 |
280 |
170 |
|
341.5 |
Day 560 |
410 |
330 |
|
440.9 |
Day 560 |
412 |
330 |
|
350.8 |
Day 560 |
414 |
330 |
|
305.7 |
Day 560 |
420 |
330 |
|
370.9 |
Day 560 |
422 |
330 |
|
358.4 |
Day 560 |
427 |
330 |
|
283.5 |
Day 561 |
244 |
170 |
|
332.1 |
Day 561 |
258 |
170 |
|
367.2 |
Day 561 |
271 |
170 |
|
369.9 |
Day 561 |
273 |
170 |
|
359.1 |
Day 561 |
274 |
170 |
|
390.3 |
Day 561 |
439 |
330 |
|
312.9 |
Day 562 |
240 |
170 |
|
396.2 |
Day 562 |
261 |
170 |
|
349.9 |
Day 562 |
299 |
170 |
|
315.3 |
Day 573 |
29 |
0 |
|
258.9 |
Day 578 |
158 |
80 |
|
317 |
Day 578 |
239 |
170 |
|
280.1 |
Day 578 |
265 |
170 |
|
280.6 |
Day 581 |
17 |
0 |
|
227.3 |
Day 581 |
302 |
170 |
|
278.7 |
Day 585 |
173 |
80 |
|
274.5 |
Day 585 |
435 |
330 |
|
238.7 |
Day 588 |
179 |
80 |
|
293.7 |
Day 590 |
432 |
330 |
|
307.3 |
Day 591 |
231 |
170 |
|
387.1 |
Day 592 |
417 |
330 |
|
300.8 |
Day 593 |
180 |
80 |
|
273 |
Day 594 |
245 |
170 |
|
263.4 |
Day 595 |
170 |
80 |
|
288.3 |
Day 595 |
405 |
330 |
|
251.6 |
Day 596 |
145 |
80 |
|
396.2 |
Day 596 |
156 |
80 |
|
294.3 |
Day 596 |
293 |
170 |
|
313.6 |
Day 597 |
408 |
330 |
|
307.1 |
Day 602 |
160 |
80 |
|
268.2 |
Day 603 |
44 |
0 |
|
384.2 |
Day 603 |
63 |
0 |
|
326.4 |
Day 603 |
152 |
80 |
|
382.1 |
Day 603 |
155 |
80 |
|
374.3 |
Day 603 |
284 |
170 |
|
346.9 |
Day 604 |
177 |
80 |
|
389.5 |
Day 604 |
270 |
170 |
|
363.2 |
Day 606 |
176 |
80 |
|
267.6 |
Day 609 |
166 |
80 |
|
355.9 |
Day 610 |
153 |
80 |
|
308.1 |
Day 611 |
159 |
80 |
|
261.5 |
Day 616 |
64 |
0 |
|
278.8 |
Day 616 |
253 |
170 |
|
422.8 |
Day 616 |
257 |
170 |
|
355.4 |
Day 616 |
276 |
170 |
|
371.9 |
Day 616 |
298 |
170 |
|
371.7 |
Day 618 |
147 |
80 |
|
382 |
Day 618 |
149 |
80 |
|
383.2 |
Day 618 |
163 |
80 |
|
377.7 |
Day 618 |
169 |
80 |
|
387.3 |
Day 629 |
40 |
0 |
|
437.8 |
Day 632 |
282 |
170 |
|
372.7 |
Day 634 |
237 |
170 |
|
339.8 |
Day 638 |
185 |
80 |
|
289.3 |
Day 640 |
25 |
0 |
|
212.9 |
Day 641 |
157 |
80 |
|
354.5 |
Day 641 |
250 |
170 |
|
293.1 |
Day 644 |
54 |
0 |
|
364.1 |
Day 644 |
142 |
80 |
|
378.4 |
Day 644 |
146 |
80 |
|
322.5 |
Day 644 |
295 |
170 |
|
369.4 |
Day 645 |
19 |
0 |
|
333.1 |
Day 645 |
55 |
0 |
|
434.2 |
Day 646 |
37 |
0 |
|
351.6 |
Day 647 |
11 |
0 |
|
431 |
Day 647 |
12 |
0 |
|
402.8 |
Day 647 |
18 |
0 |
|
404.6 |
Day 647 |
20 |
0 |
|
386.8 |
Day 647 |
21 |
0 |
|
378.2 |
Day 647 |
22 |
0 |
|
390.3 |
Day 647 |
23 |
0 |
|
390.8 |
Day 647 |
24 |
0 |
|
432.7 |
Day 647 |
26 |
0 |
|
383.1 |
Day 647 |
27 |
0 |
|
421.5 |
Day 647 |
28 |
0 |
|
378.1 |
Day 647 |
30 |
0 |
|
399.4 |
Day 647 |
31 |
0 |
|
396.5 |
Day 647 |
32 |
0 |
|
401.3 |
Day 647 |
33 |
0 |
|
369.4 |
Day 647 |
34 |
0 |
|
400.4 |
Day 647 |
35 |
0 |
|
430.9 |
Day 647 |
36 |
0 |
|
440.1 |
Day 647 |
38 |
0 |
|
447.5 |
Day 647 |
39 |
0 |
|
419 |
Day 647 |
41 |
0 |
|
439.1 |
Day 647 |
43 |
0 |
|
426.6 |
Day 647 |
45 |
0 |
|
428.5 |
Day 647 |
46 |
0 |
|
430.2 |
Day 647 |
47 |
0 |
|
364.9 |
Day 647 |
48 |
0 |
|
416.4 |
Day 647 |
49 |
0 |
|
440.7 |
Day 647 |
50 |
0 |
|
239.9 |
Day 647 |
51 |
0 |
|
427.1 |
Day 647 |
52 |
0 |
|
419.8 |
Day 647 |
53 |
0 |
|
355.6 |
Day 647 |
56 |
0 |
|
414.4 |
Day 647 |
57 |
0 |
|
395.9 |
Day 647 |
58 |
0 |
|
390.7 |
Day 647 |
59 |
0 |
|
417.9 |
Day 647 |
60 |
0 |
|
430.3 |
Day 647 |
61 |
0 |
|
420.8 |
Day 647 |
62 |
0 |
|
426.6 |
Day 647 |
65 |
0 |
|
410.9 |
Day 647 |
66 |
0 |
|
446 |
Day 647 |
67 |
0 |
|
405.1 |
Day 647 |
68 |
0 |
|
391.2 |
Day 647 |
69 |
0 |
|
388.8 |
Day 647 |
70 |
0 |
|
411.8 |
Day 647 |
150 |
80 |
|
413 |
Day 647 |
167 |
80 |
|
370.6 |
Day 647 |
172 |
80 |
|
372.5 |
Day 647 |
174 |
80 |
|
381 |
Day 647 |
181 |
80 |
|
409.4 |
Day 647 |
182 |
80 |
|
383 |
Day 647 |
183 |
80 |
|
394.1 |
Day 647 |
184 |
80 |
|
394 |
Abbreviations: |
NA: Not Available
|