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Current Search Critera
Short-Term Study
Individual Animal Clinical Observations
Study Information:
Chemical Name: | 4-(6-Methyl-2-benzothiazolyl)-benzenamine |
CASRN: | ="92-36-4" |
Study Number: | C61745 |
Exposure Route: | |
TDMS Number: | 0514003 |
Sex: | Female |
Strain and Species: | F 344/N Rats |
Animal Number |
Dose Group |
Clinical Observation |
Qualifier |
Incident Number |
Observation Date |
First Dose Date |
Days On Study |
Removal Observation |
64 |
Untreated Control |
Lacrimation |
|
|
07/22/1986 |
07/15/86 |
8.00 |
No |
64 |
Untreated Control |
Reddened Eye |
|
|
09/09/1986 |
07/15/86 |
57.00 |
No |
64 |
Untreated Control |
Reddened Eye |
|
|
09/16/1986 |
07/15/86 |
64.00 |
No |
66 |
Untreated Control |
Alopecia |
|
|
09/09/1986 |
07/15/86 |
57.00 |
No |
66 |
Untreated Control |
Alopecia |
|
|
09/16/1986 |
07/15/86 |
64.00 |
No |
67 |
Untreated Control |
Alopecia |
|
|
09/09/1986 |
07/15/86 |
57.00 |
No |
67 |
Untreated Control |
Alopecia |
|
|
09/16/1986 |
07/15/86 |
64.00 |
No |
69 |
Untreated Control |
Lacrimation |
|
|
07/22/1986 |
07/15/86 |
8.00 |
No |
74 |
0.00625 % |
Hyperactive |
|
|
07/29/1986 |
07/15/86 |
15.00 |
No |
75 |
0.00625 % |
Hyperactive |
|
|
07/29/1986 |
07/15/86 |
15.00 |
No |
75 |
0.00625 % |
Fractured Appendage |
Tail |
|
09/23/1986 |
07/15/86 |
71.00 |
No |
75 |
0.00625 % |
Fractured Appendage |
Tail |
|
09/30/1986 |
07/15/86 |
78.00 |
No |
75 |
0.00625 % |
Fractured Appendage |
Tail |
|
10/07/1986 |
07/15/86 |
85.00 |
No |
75 |
0.00625 % |
Missing Anatomy |
Tail |
|
10/17/1986 |
07/15/86 |
95.00 |
Yes |
76 |
0.00625 % |
Reddened Eye |
|
|
07/29/1986 |
07/15/86 |
15.00 |
No |
77 |
0.00625 % |
Reddened Eye |
|
|
07/29/1986 |
07/15/86 |
15.00 |
No |
77 |
0.00625 % |
Lacrimation |
|
|
07/29/1986 |
07/15/86 |
15.00 |
No |
81 |
0.0125 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
81 |
0.0125 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
81 |
0.0125 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
82 |
0.0125 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
82 |
0.0125 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
82 |
0.0125 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
84 |
0.0125 % |
Reddened Eye |
|
|
09/02/1986 |
07/15/86 |
50.00 |
No |
84 |
0.0125 % |
Reddened Eye |
|
|
09/09/1986 |
07/15/86 |
57.00 |
No |
84 |
0.0125 % |
Lacrimation |
|
|
09/16/1986 |
07/15/86 |
64.00 |
No |
84 |
0.0125 % |
Reddened Eye |
|
|
09/16/1986 |
07/15/86 |
64.00 |
No |
84 |
0.0125 % |
Micro-Ophthalmia |
|
|
09/16/1986 |
07/15/86 |
64.00 |
No |
85 |
0.0125 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
85 |
0.0125 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
85 |
0.0125 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
91 |
0.025 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
91 |
0.025 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
91 |
0.025 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
92 |
0.025 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
92 |
0.025 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
92 |
0.025 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
93 |
0.025 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
93 |
0.025 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
93 |
0.025 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
94 |
0.025 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
94 |
0.025 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
94 |
0.025 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
95 |
0.025 % |
Fractured Appendage |
Tail |
|
09/09/1986 |
07/15/86 |
57.00 |
No |
95 |
0.025 % |
Fractured Appendage |
Tail |
|
09/16/1986 |
07/15/86 |
64.00 |
No |
95 |
0.025 % |
Fractured Appendage |
Tail |
|
09/23/1986 |
07/15/86 |
71.00 |
No |
95 |
0.025 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
95 |
0.025 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
95 |
0.025 % |
Fractured Appendage |
Tail |
|
09/30/1986 |
07/15/86 |
78.00 |
No |
95 |
0.025 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
95 |
0.025 % |
Fractured Appendage |
Tail |
|
10/07/1986 |
07/15/86 |
85.00 |
No |
96 |
0.025 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
96 |
0.025 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
96 |
0.025 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
97 |
0.025 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
97 |
0.025 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
97 |
0.025 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
98 |
0.025 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
98 |
0.025 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
98 |
0.025 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
99 |
0.025 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
99 |
0.025 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
99 |
0.025 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
100 |
0.025 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
100 |
0.025 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
100 |
0.025 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
101 |
0.05 % |
Pallor |
|
|
09/02/1986 |
07/15/86 |
50.00 |
No |
101 |
0.05 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
101 |
0.05 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
101 |
0.05 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
102 |
0.05 % |
Pallor |
|
|
09/02/1986 |
07/15/86 |
50.00 |
No |
102 |
0.05 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
102 |
0.05 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
102 |
0.05 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
103 |
0.05 % |
Pallor |
|
|
09/02/1986 |
07/15/86 |
50.00 |
No |
103 |
0.05 % |
Pallor |
|
|
09/16/1986 |
07/15/86 |
64.00 |
No |
103 |
0.05 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
103 |
0.05 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
103 |
0.05 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
104 |
0.05 % |
Pallor |
|
|
09/02/1986 |
07/15/86 |
50.00 |
No |
104 |
0.05 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
104 |
0.05 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
104 |
0.05 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
105 |
0.05 % |
Pallor |
|
|
09/02/1986 |
07/15/86 |
50.00 |
No |
105 |
0.05 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
105 |
0.05 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
105 |
0.05 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
106 |
0.05 % |
Pallor |
|
|
09/16/1986 |
07/15/86 |
64.00 |
No |
106 |
0.05 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
106 |
0.05 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
106 |
0.05 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
107 |
0.05 % |
Pallor |
|
|
09/02/1986 |
07/15/86 |
50.00 |
No |
107 |
0.05 % |
Hyperactive |
|
|
09/16/1986 |
07/15/86 |
64.00 |
No |
107 |
0.05 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
107 |
0.05 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
107 |
0.05 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
108 |
0.05 % |
Hyperactive |
|
|
07/22/1986 |
07/15/86 |
8.00 |
No |
108 |
0.05 % |
Pallor |
|
|
09/02/1986 |
07/15/86 |
50.00 |
No |
108 |
0.05 % |
Pallor |
|
|
09/16/1986 |
07/15/86 |
64.00 |
No |
108 |
0.05 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
108 |
0.05 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
108 |
0.05 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
109 |
0.05 % |
Hyperactive |
|
|
07/22/1986 |
07/15/86 |
8.00 |
No |
109 |
0.05 % |
Pallor |
|
|
09/02/1986 |
07/15/86 |
50.00 |
No |
109 |
0.05 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
109 |
0.05 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
109 |
0.05 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
110 |
0.05 % |
Pallor |
|
|
09/02/1986 |
07/15/86 |
50.00 |
No |
110 |
0.05 % |
Pallor |
|
|
09/16/1986 |
07/15/86 |
64.00 |
No |
110 |
0.05 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
110 |
0.05 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
110 |
0.05 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
111 |
0.1 % |
Pallor |
|
|
09/02/1986 |
07/15/86 |
50.00 |
No |
111 |
0.1 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
111 |
0.1 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
111 |
0.1 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
112 |
0.1 % |
Pallor |
|
|
09/02/1986 |
07/15/86 |
50.00 |
No |
112 |
0.1 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
112 |
0.1 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
112 |
0.1 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
113 |
0.1 % |
Pallor |
|
|
09/02/1986 |
07/15/86 |
50.00 |
No |
113 |
0.1 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
113 |
0.1 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
113 |
0.1 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
114 |
0.1 % |
Pallor |
|
|
09/02/1986 |
07/15/86 |
50.00 |
No |
114 |
0.1 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
114 |
0.1 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
114 |
0.1 % |
Hyperactive |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
114 |
0.1 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
114 |
0.1 % |
Hyperactive |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
115 |
0.1 % |
Pallor |
|
|
09/02/1986 |
07/15/86 |
50.00 |
No |
115 |
0.1 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
115 |
0.1 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
115 |
0.1 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
116 |
0.1 % |
Pallor |
|
|
09/02/1986 |
07/15/86 |
50.00 |
No |
116 |
0.1 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
116 |
0.1 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
116 |
0.1 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
117 |
0.1 % |
Pallor |
|
|
09/02/1986 |
07/15/86 |
50.00 |
No |
117 |
0.1 % |
Hyperactive |
|
|
09/16/1986 |
07/15/86 |
64.00 |
No |
117 |
0.1 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
117 |
0.1 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
117 |
0.1 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
118 |
0.1 % |
Pallor |
|
|
09/02/1986 |
07/15/86 |
50.00 |
No |
118 |
0.1 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
118 |
0.1 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
118 |
0.1 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
119 |
0.1 % |
Pallor |
|
|
09/02/1986 |
07/15/86 |
50.00 |
No |
119 |
0.1 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
119 |
0.1 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
119 |
0.1 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |
120 |
0.1 % |
Pallor |
|
|
09/02/1986 |
07/15/86 |
50.00 |
No |
120 |
0.1 % |
Pallor |
|
|
09/23/1986 |
07/15/86 |
71.00 |
No |
120 |
0.1 % |
Pallor |
|
|
09/30/1986 |
07/15/86 |
78.00 |
No |
120 |
0.1 % |
Pallor |
|
|
10/07/1986 |
07/15/86 |
85.00 |
No |