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Short-Term Individual Animal Non Neoplastic Diagnosis
Study Information:
Chemical Name: | Aloe vera whole leaf extract (native) |
CASRN: | ="ALOEVLEAFEXT" |
Study Number: | C20116B |
Exposure Route: | DOSED WATER |
TDMS Number: | 2011601 |
Sex: | Female |
Strain and Species: | F 344/N Rats |
Female Individual Animal Non Neoplastic Diagnoses
System |
Organ |
Site |
Treatment Group |
Number Examined |
Cage Number |
Animal Number |
Days on Study |
Lesion Found |
Lesion Name |
Lesion Qualifier |
Removal Reason |
Alimentary System |
Intestine Large |
Cecum |
1 % |
12 |
41 |
411 |
101 |
1 |
Infiltration Cellular |
Minimal, Polymorphnuclr |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum |
3 % |
11 |
31 |
311 |
100 |
1 |
Infiltration Cellular |
Minimal, Polymorphnuclr |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum |
3 % |
11 |
32 |
321 |
100 |
1 |
Infiltration Cellular |
Mild, Polymorphnuclr |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
Vehicle Control |
12 |
28 |
281 |
101 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
1 % |
12 |
37 |
371 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
1 % |
12 |
38 |
381 |
100 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
1 % |
12 |
38 |
382 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
1 % |
12 |
40 |
401 |
101 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
1 % |
12 |
41 |
411 |
101 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
1 % |
12 |
42 |
421 |
101 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
2 % |
12 |
43 |
431 |
100 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
2 % |
12 |
43 |
432 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
2 % |
12 |
44 |
441 |
100 |
1 |
Hyperplasia |
Marked |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
2 % |
12 |
45 |
452 |
100 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
2 % |
12 |
46 |
462 |
101 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
2 % |
12 |
47 |
472 |
101 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
2 % |
12 |
48 |
481 |
101 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
2 % |
12 |
48 |
482 |
101 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
3 % |
11 |
31 |
311 |
100 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
3 % |
11 |
31 |
312 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
3 % |
11 |
32 |
321 |
100 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
3 % |
11 |
33 |
332 |
100 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon |
1 % |
12 |
39 |
392 |
100 |
1 |
Infiltration Cellular |
Mild, Polymorphnuclr |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon |
1 % |
12 |
41 |
411 |
101 |
1 |
Infiltration Cellular |
Minimal, Polymorphnuclr |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon |
2 % |
12 |
45 |
451 |
46 |
1 |
Infiltration Cellular |
Mild, Lymphoid |
Moribund Sacrifice |
Alimentary System |
Intestine Large |
Colon |
2 % |
12 |
43 |
431 |
100 |
1 |
Infiltration Cellular |
Minimal, Polymorphnuclr |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon |
2 % |
12 |
44 |
441 |
100 |
1 |
Infiltration Cellular |
Minimal, Polymorphnuclr |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon |
2 % |
12 |
46 |
462 |
101 |
1 |
Infiltration Cellular |
Mild, Polymorphnuclr |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon |
2 % |
12 |
48 |
482 |
101 |
1 |
Infiltration Cellular |
Mild, Polymorphnuclr |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon |
3 % |
11 |
33 |
332 |
100 |
1 |
Infiltration Cellular |
Moderate, Polymorphnuclr |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
1 % |
12 |
37 |
371 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
1 % |
12 |
37 |
372 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
1 % |
12 |
38 |
381 |
100 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
1 % |
12 |
38 |
382 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
1 % |
12 |
39 |
392 |
100 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
1 % |
12 |
40 |
401 |
101 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
1 % |
12 |
41 |
411 |
101 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
1 % |
12 |
42 |
421 |
101 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
2 % |
12 |
45 |
451 |
46 |
1 |
Hyperplasia |
Mild |
Moribund Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
2 % |
12 |
43 |
431 |
100 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
2 % |
12 |
43 |
432 |
100 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
2 % |
12 |
44 |
441 |
100 |
1 |
Hyperplasia |
Marked |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
2 % |
12 |
45 |
452 |
100 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
2 % |
12 |
46 |
462 |
101 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
2 % |
12 |
47 |
472 |
101 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
2 % |
12 |
48 |
481 |
101 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
2 % |
12 |
48 |
482 |
101 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
3 % |
11 |
31 |
311 |
100 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
3 % |
11 |
31 |
312 |
100 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
3 % |
11 |
32 |
321 |
100 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
3 % |
11 |
33 |
332 |
100 |
1 |
Hyperplasia |
Marked |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Rectum, Anus |
2 % |
12 |
43 |
431 |
100 |
1 |
Hyperplasia |
Moderate, Squamous |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Rectum, Anus |
2 % |
12 |
47 |
472 |
101 |
1 |
Hyperplasia |
Mild, Squamous |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Rectum, Anus |
2 % |
12 |
43 |
431 |
100 |
1 |
Inflammation |
Moderate, Chronic Active |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Rectum, Anus |
2 % |
12 |
47 |
472 |
101 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Rectum, Anus |
3 % |
11 |
31 |
311 |
100 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Rectum, Anus, Epithelium |
3 % |
11 |
31 |
311 |
100 |
1 |
Hyperplasia |
Moderate, Squamous |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Rectum, Goblet Cell |
2 % |
12 |
43 |
431 |
100 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Rectum, Goblet Cell |
2 % |
12 |
43 |
432 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Rectum, Goblet Cell |
2 % |
12 |
45 |
452 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Rectum, Goblet Cell |
2 % |
12 |
46 |
462 |
101 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Rectum, Goblet Cell |
2 % |
12 |
47 |
472 |
101 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Rectum, Goblet Cell |
2 % |
12 |
48 |
481 |
101 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Rectum, Goblet Cell |
2 % |
12 |
48 |
482 |
101 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Rectum, Goblet Cell |
3 % |
11 |
31 |
311 |
100 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Rectum, Goblet Cell |
3 % |
11 |
32 |
321 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Rectum, Goblet Cell |
3 % |
11 |
33 |
332 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Small |
Ileum, Goblet Cell |
3 % |
11 |
32 |
321 |
100 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
|
1 % |
12 |
38 |
381 |
100 |
1 |
Deformity |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
3 % |
11 |
36 |
361 |
34 |
1 |
Hepatodiaphragmatic Nodule |
|
Moribund Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
12 |
29 |
292 |
101 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Alimentary System |
Liver |
|
3 % |
11 |
31 |
312 |
100 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Alimentary System |
Liver |
|
1 % |
12 |
41 |
411 |
101 |
1 |
Vacuolization Cytoplasmic |
Minimal |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach |
2 % |
12 |
44 |
442 |
31 |
1 |
Hyperkeratosis |
Minimal |
Moribund Sacrifice |
Alimentary System |
Stomach |
Forestomach |
2 % |
12 |
46 |
461 |
31 |
1 |
Hyperkeratosis |
Mild |
Moribund Sacrifice |
Alimentary System |
Stomach |
Forestomach |
3 % |
11 |
34 |
341 |
26 |
1 |
Hyperkeratosis |
Minimal |
Moribund Sacrifice |
Alimentary System |
Stomach |
Forestomach |
3 % |
11 |
36 |
362 |
34 |
1 |
Hyperkeratosis |
Minimal |
Moribund Sacrifice |
Cardiovascular System |
Heart |
|
2 % |
12 |
45 |
452 |
100 |
1 |
Inflammation |
Marked, Chronic Active |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
2 % |
12 |
45 |
452 |
100 |
1 |
Polyarteritis |
Marked |
Terminal Sacrifice |
Genital System |
Clitoral Gland |
Duct |
2 % |
12 |
46 |
461 |
31 |
1 |
Dilatation |
Marked |
Moribund Sacrifice |
Genital System |
Clitoral Gland |
Duct |
2 % |
12 |
43 |
431 |
100 |
1 |
Dilatation |
Mild |
Terminal Sacrifice |
Genital System |
Clitoral Gland |
|
Vehicle Control |
12 |
25 |
252 |
100 |
1 |
Infiltration Cellular |
Mild, Lymphoid |
Terminal Sacrifice |
Genital System |
Clitoral Gland |
|
Vehicle Control |
12 |
27 |
271 |
100 |
1 |
Infiltration Cellular |
Mild, Lymphoid |
Terminal Sacrifice |
Genital System |
Clitoral Gland |
|
Vehicle Control |
12 |
28 |
281 |
101 |
1 |
Infiltration Cellular |
Moderate, Lymphoid |
Terminal Sacrifice |
Genital System |
Clitoral Gland |
|
Vehicle Control |
12 |
30 |
302 |
101 |
1 |
Infiltration Cellular |
Minimal, Lymphoid |
Terminal Sacrifice |
Genital System |
Clitoral Gland |
|
3 % |
11 |
32 |
322 |
31 |
1 |
Infiltration Cellular |
Minimal, Lymphoid |
Moribund Sacrifice |
Genital System |
Clitoral Gland |
|
Vehicle Control |
12 |
25 |
251 |
100 |
1 |
Inflammation |
Mild, Suppurative |
Terminal Sacrifice |
Genital System |
Clitoral Gland |
|
Vehicle Control |
12 |
26 |
261 |
100 |
1 |
Inflammation |
Mild, Suppurative |
Terminal Sacrifice |
Genital System |
Clitoral Gland |
|
Vehicle Control |
12 |
28 |
282 |
101 |
1 |
Inflammation |
Moderate, Suppurative |
Terminal Sacrifice |
Genital System |
Clitoral Gland |
|
Vehicle Control |
12 |
29 |
291 |
101 |
1 |
Inflammation |
Minimal, Suppurative |
Terminal Sacrifice |
Genital System |
Clitoral Gland |
|
2 % |
12 |
45 |
451 |
46 |
1 |
Inflammation |
Mild, Suppurative |
Moribund Sacrifice |
Genital System |
Clitoral Gland |
|
2 % |
12 |
46 |
461 |
31 |
1 |
Inflammation |
Marked, Suppurative |
Moribund Sacrifice |
Genital System |
Clitoral Gland |
|
2 % |
12 |
47 |
471 |
31 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund Sacrifice |
Genital System |
Clitoral Gland |
|
2 % |
12 |
43 |
431 |
100 |
1 |
Inflammation |
Mild, Suppurative |
Terminal Sacrifice |
Genital System |
Clitoral Gland |
|
2 % |
12 |
46 |
462 |
101 |
1 |
Inflammation |
Mild, Suppurative |
Terminal Sacrifice |
Genital System |
Clitoral Gland |
|
2 % |
12 |
48 |
481 |
101 |
1 |
Inflammation |
Minimal, Suppurative |
Terminal Sacrifice |
Genital System |
Clitoral Gland |
|
2 % |
12 |
48 |
482 |
101 |
1 |
Inflammation |
Moderate, Suppurative |
Terminal Sacrifice |
Genital System |
Clitoral Gland |
|
3 % |
11 |
34 |
341 |
26 |
1 |
Inflammation |
Minimal, Suppurative |
Moribund Sacrifice |
Genital System |
Clitoral Gland |
|
3 % |
11 |
34 |
342 |
31 |
1 |
Inflammation |
Marked, Suppurative |
Moribund Sacrifice |
Genital System |
Clitoral Gland |
|
3 % |
11 |
35 |
351 |
31 |
1 |
Inflammation |
Moderate, Suppurative |
Moribund Sacrifice |
Genital System |
Clitoral Gland |
|
3 % |
11 |
35 |
352 |
31 |
1 |
Inflammation |
Moderate, Suppurative |
Moribund Sacrifice |
Genital System |
Clitoral Gland |
|
3 % |
11 |
36 |
361 |
34 |
1 |
Inflammation |
Mild, Suppurative |
Moribund Sacrifice |
Genital System |
Clitoral Gland |
|
3 % |
11 |
31 |
311 |
100 |
1 |
Inflammation |
Moderate, Suppurative |
Terminal Sacrifice |
Genital System |
Clitoral Gland |
|
3 % |
11 |
31 |
312 |
100 |
1 |
Inflammation |
Mild, Suppurative |
Terminal Sacrifice |
Genital System |
Clitoral Gland |
|
3 % |
11 |
32 |
321 |
100 |
1 |
Inflammation |
Mild, Suppurative |
Terminal Sacrifice |
Genital System |
Clitoral Gland |
|
3 % |
11 |
33 |
332 |
100 |
1 |
Inflammation |
Minimal, Suppurative |
Terminal Sacrifice |
Genital System |
Ovary |
Interstit Cell |
2 % |
12 |
47 |
472 |
101 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Ovary |
Interstit Cell |
2 % |
12 |
48 |
481 |
101 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Ovary |
Interstit Cell |
3 % |
11 |
32 |
321 |
100 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Ovary |
|
2 % |
12 |
45 |
451 |
46 |
1 |
Hypoplasia |
Mild |
Moribund Sacrifice |
Genital System |
Ovary |
|
2 % |
12 |
47 |
471 |
31 |
1 |
Hypoplasia |
Moderate |
Moribund Sacrifice |
Genital System |
Ovary |
|
3 % |
11 |
34 |
341 |
26 |
1 |
Hypoplasia |
Moderate |
Moribund Sacrifice |
Genital System |
Ovary |
|
3 % |
11 |
34 |
342 |
31 |
1 |
Hypoplasia |
Minimal |
Moribund Sacrifice |
Genital System |
Ovary |
|
3 % |
11 |
35 |
351 |
31 |
1 |
Hypoplasia |
Moderate |
Moribund Sacrifice |
Genital System |
Ovary |
|
3 % |
11 |
36 |
361 |
34 |
1 |
Hypoplasia |
Moderate |
Moribund Sacrifice |
Genital System |
Ovary |
|
3 % |
11 |
36 |
362 |
34 |
1 |
Hypoplasia |
Moderate |
Moribund Sacrifice |
Genital System |
Uterus |
Lumen |
Vehicle Control |
12 |
25 |
251 |
100 |
1 |
Dilatation |
Marked |
Terminal Sacrifice |
Genital System |
Uterus |
Lumen |
Vehicle Control |
12 |
25 |
252 |
100 |
1 |
Dilatation |
Mild |
Terminal Sacrifice |
Genital System |
Uterus |
Lumen |
Vehicle Control |
12 |
26 |
261 |
100 |
1 |
Dilatation |
Mild |
Terminal Sacrifice |
Genital System |
Uterus |
Lumen |
1 % |
2 |
38 |
382 |
100 |
1 |
Dilatation |
Marked |
Terminal Sacrifice |
Genital System |
Uterus |
Lumen |
1 % |
2 |
39 |
391 |
100 |
1 |
Dilatation |
Marked |
Terminal Sacrifice |
Genital System |
Uterus |
Lumen |
2 % |
12 |
43 |
432 |
100 |
1 |
Dilatation |
Moderate |
Terminal Sacrifice |
Genital System |
Uterus |
|
2 % |
12 |
45 |
451 |
46 |
1 |
Hypoplasia |
Mild |
Moribund Sacrifice |
Genital System |
Uterus |
|
2 % |
12 |
47 |
471 |
31 |
1 |
Hypoplasia |
Mild |
Moribund Sacrifice |
Genital System |
Uterus |
|
3 % |
11 |
34 |
341 |
26 |
1 |
Hypoplasia |
Moderate |
Moribund Sacrifice |
Genital System |
Uterus |
|
3 % |
11 |
34 |
342 |
31 |
1 |
Hypoplasia |
Minimal |
Moribund Sacrifice |
Genital System |
Uterus |
|
3 % |
11 |
35 |
351 |
31 |
1 |
Hypoplasia |
Moderate |
Moribund Sacrifice |
Genital System |
Uterus |
|
3 % |
11 |
36 |
361 |
34 |
1 |
Hypoplasia |
Moderate |
Moribund Sacrifice |
Genital System |
Uterus |
|
3 % |
11 |
36 |
362 |
34 |
1 |
Hypoplasia |
Moderate |
Moribund Sacrifice |
Genital System |
Vagina |
Lumen |
3 % |
1 |
34 |
342 |
31 |
1 |
Dilatation |
Moderate |
Moribund Sacrifice |
Hematopoietic System |
Bone Marrow |
|
2 % |
12 |
44 |
442 |
31 |
1 |
Hypocellularity |
Marked |
Moribund Sacrifice |
Hematopoietic System |
Bone Marrow |
|
2 % |
12 |
45 |
451 |
46 |
1 |
Hypocellularity |
Mild |
Moribund Sacrifice |
Hematopoietic System |
Bone Marrow |
|
2 % |
12 |
46 |
461 |
31 |
1 |
Hypocellularity |
Moderate |
Moribund Sacrifice |
Hematopoietic System |
Bone Marrow |
|
2 % |
12 |
47 |
471 |
31 |
1 |
Hypocellularity |
Marked |
Moribund Sacrifice |
Hematopoietic System |
Bone Marrow |
|
3 % |
11 |
32 |
322 |
31 |
1 |
Hypocellularity |
Moderate |
Moribund Sacrifice |
Hematopoietic System |
Bone Marrow |
|
3 % |
11 |
34 |
341 |
26 |
1 |
Hypocellularity |
Moderate |
Moribund Sacrifice |
Hematopoietic System |
Bone Marrow |
|
3 % |
11 |
34 |
342 |
31 |
1 |
Hypocellularity |
Moderate |
Moribund Sacrifice |
Hematopoietic System |
Bone Marrow |
|
3 % |
11 |
35 |
351 |
31 |
1 |
Hypocellularity |
Moderate |
Moribund Sacrifice |
Hematopoietic System |
Bone Marrow |
|
3 % |
11 |
35 |
352 |
31 |
1 |
Hypocellularity |
Marked |
Moribund Sacrifice |
Hematopoietic System |
Bone Marrow |
|
3 % |
11 |
36 |
361 |
34 |
1 |
Hypocellularity |
Moderate |
Moribund Sacrifice |
Hematopoietic System |
Bone Marrow |
|
3 % |
11 |
36 |
362 |
34 |
1 |
Hypocellularity |
Mild |
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Lumbar |
2 % |
12 |
46 |
461 |
31 |
1 |
Hyperplasia |
Minimal, Lymphoid |
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Mandibular |
Vehicle Control |
12 |
25 |
251 |
100 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
2 % |
12 |
43 |
431 |
100 |
1 |
Degeneration |
Marked, Cystic |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
Vehicle Control |
12 |
25 |
251 |
100 |
1 |
Hyperplasia |
Moderate, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
Vehicle Control |
12 |
25 |
252 |
100 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
Vehicle Control |
12 |
26 |
261 |
100 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
Vehicle Control |
12 |
27 |
271 |
100 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
Vehicle Control |
12 |
27 |
272 |
100 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
Vehicle Control |
12 |
28 |
281 |
101 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
Vehicle Control |
12 |
29 |
292 |
101 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
Vehicle Control |
12 |
30 |
301 |
101 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
Vehicle Control |
12 |
30 |
302 |
101 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
1 % |
4 |
38 |
381 |
100 |
1 |
Hyperplasia |
Marked, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
1 % |
4 |
39 |
392 |
100 |
1 |
Hyperplasia |
Marked, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
1 % |
4 |
41 |
412 |
101 |
1 |
Hyperplasia |
Marked, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
1 % |
4 |
42 |
422 |
101 |
1 |
Hyperplasia |
Marked, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
2 % |
12 |
43 |
431 |
100 |
1 |
Hyperplasia |
Marked, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
2 % |
12 |
43 |
432 |
100 |
1 |
Hyperplasia |
Marked, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
2 % |
12 |
44 |
441 |
100 |
1 |
Hyperplasia |
Moderate, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
2 % |
12 |
45 |
452 |
100 |
1 |
Hyperplasia |
Moderate, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
2 % |
12 |
46 |
462 |
101 |
1 |
Hyperplasia |
Marked, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
2 % |
12 |
47 |
472 |
101 |
1 |
Hyperplasia |
Marked, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
2 % |
12 |
48 |
481 |
101 |
1 |
Hyperplasia |
Marked, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
2 % |
12 |
48 |
482 |
101 |
1 |
Hyperplasia |
Moderate, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
3 % |
11 |
31 |
311 |
100 |
1 |
Hyperplasia |
Marked, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
3 % |
11 |
31 |
312 |
100 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
3 % |
11 |
32 |
321 |
100 |
1 |
Hyperplasia |
Marked, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
3 % |
11 |
33 |
332 |
100 |
1 |
Hyperplasia |
Marked, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
1 % |
12 |
37 |
371 |
100 |
1 |
Inflammation |
Marked, Chronic Active |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
2 % |
12 |
44 |
442 |
31 |
1 |
Atrophy |
Marked |
Moribund Sacrifice |
Hematopoietic System |
Thymus |
|
2 % |
12 |
45 |
451 |
46 |
1 |
Atrophy |
Mild |
Moribund Sacrifice |
Hematopoietic System |
Thymus |
|
2 % |
12 |
45 |
452 |
100 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
2 % |
12 |
47 |
472 |
101 |
1 |
Atrophy |
Moderate |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
3 % |
11 |
32 |
322 |
31 |
1 |
Atrophy |
Mild |
Moribund Sacrifice |
Hematopoietic System |
Thymus |
|
3 % |
11 |
34 |
342 |
31 |
1 |
Atrophy |
Marked |
Moribund Sacrifice |
Hematopoietic System |
Thymus |
|
3 % |
11 |
35 |
351 |
31 |
1 |
Atrophy |
Marked |
Moribund Sacrifice |
Hematopoietic System |
Thymus |
|
3 % |
11 |
35 |
352 |
31 |
1 |
Atrophy |
Moderate |
Moribund Sacrifice |
Hematopoietic System |
Thymus |
|
3 % |
11 |
36 |
361 |
34 |
1 |
Atrophy |
Mild |
Moribund Sacrifice |
Hematopoietic System |
Thymus |
|
3 % |
11 |
36 |
362 |
34 |
1 |
Atrophy |
Mild |
Moribund Sacrifice |
Special Senses System |
Harderian Gland |
|
Vehicle Control |
12 |
25 |
252 |
100 |
1 |
Infiltration Cellular |
Minimal, Lymphoid |
Terminal Sacrifice |
Special Senses System |
Harderian Gland |
|
Vehicle Control |
12 |
26 |
262 |
100 |
1 |
Infiltration Cellular |
Minimal, Lymphoid |
Terminal Sacrifice |
Special Senses System |
Harderian Gland |
|
Vehicle Control |
12 |
28 |
281 |
101 |
1 |
Infiltration Cellular |
Minimal, Lymphoid |
Terminal Sacrifice |
Special Senses System |
Harderian Gland |
|
2 % |
12 |
43 |
431 |
100 |
1 |
Infiltration Cellular |
Mild, Lymphoid |
Terminal Sacrifice |
Special Senses System |
Harderian Gland |
|
2 % |
12 |
48 |
481 |
101 |
1 |
Infiltration Cellular |
Minimal, Lymphoid |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
12 |
25 |
251 |
100 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
12 |
25 |
252 |
100 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
12 |
26 |
261 |
100 |
1 |
Mineralization |
Moderate |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
12 |
26 |
262 |
100 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
12 |
27 |
271 |
100 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
12 |
27 |
272 |
100 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
12 |
28 |
281 |
101 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
12 |
28 |
282 |
101 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
12 |
29 |
291 |
101 |
1 |
Mineralization |
Moderate |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
12 |
29 |
292 |
101 |
1 |
Mineralization |
Moderate |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
12 |
30 |
301 |
101 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
12 |
30 |
302 |
101 |
1 |
Mineralization |
Moderate |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
1 % |
12 |
37 |
371 |
100 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
1 % |
12 |
37 |
372 |
100 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
1 % |
12 |
38 |
381 |
100 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
1 % |
12 |
38 |
382 |
100 |
1 |
Mineralization |
Moderate |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
1 % |
12 |
39 |
391 |
100 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
1 % |
12 |
39 |
392 |
100 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
1 % |
12 |
40 |
401 |
101 |
1 |
Mineralization |
Moderate |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
1 % |
12 |
40 |
402 |
101 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
1 % |
12 |
41 |
411 |
101 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
1 % |
12 |
41 |
412 |
101 |
1 |
Mineralization |
Moderate |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
1 % |
12 |
42 |
421 |
101 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
1 % |
12 |
42 |
422 |
101 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
2 % |
12 |
45 |
451 |
46 |
1 |
Mineralization |
Mild |
Moribund Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
2 % |
12 |
46 |
461 |
31 |
1 |
Mineralization |
Mild |
Moribund Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
2 % |
12 |
43 |
431 |
100 |
1 |
Mineralization |
Moderate |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
2 % |
12 |
43 |
432 |
100 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
2 % |
12 |
44 |
441 |
100 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
2 % |
12 |
45 |
452 |
100 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
2 % |
12 |
46 |
462 |
101 |
1 |
Mineralization |
Moderate |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
2 % |
12 |
47 |
472 |
101 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
2 % |
12 |
48 |
482 |
101 |
1 |
Mineralization |
Moderate |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
3 % |
11 |
32 |
322 |
31 |
1 |
Mineralization |
Minimal |
Moribund Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
3 % |
11 |
34 |
342 |
31 |
1 |
Mineralization |
Mild |
Moribund Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
3 % |
11 |
35 |
352 |
31 |
1 |
Mineralization |
Moderate |
Moribund Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
3 % |
11 |
31 |
311 |
100 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
3 % |
11 |
31 |
312 |
100 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
3 % |
11 |
32 |
321 |
100 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
3 % |
11 |
33 |
332 |
100 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
1 % |
12 |
37 |
371 |
100 |
1 |
Nephropathy |
Minimal, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
1 % |
12 |
37 |
372 |
100 |
1 |
Nephropathy |
Minimal, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
1 % |
12 |
39 |
391 |
100 |
1 |
Nephropathy |
Minimal, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
1 % |
12 |
39 |
392 |
100 |
1 |
Nephropathy |
Minimal, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
1 % |
12 |
40 |
402 |
101 |
1 |
Nephropathy |
Minimal, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
1 % |
12 |
41 |
411 |
101 |
1 |
Nephropathy |
Minimal, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
1 % |
12 |
41 |
412 |
101 |
1 |
Nephropathy |
Minimal, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
2 % |
12 |
43 |
432 |
100 |
1 |
Nephropathy |
Minimal, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
2 % |
12 |
46 |
462 |
101 |
1 |
Nephropathy |
Minimal, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
2 % |
12 |
48 |
481 |
101 |
1 |
Nephropathy |
Minimal, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
3 % |
11 |
31 |
312 |
100 |
1 |
Nephropathy |
Minimal, Chronic |
Terminal Sacrifice |