Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
1 % |
12 |
2 |
24 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
2 % |
12 |
19 |
191 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
2 % |
12 |
20 |
201 |
100 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
2 % |
12 |
21 |
211 |
101 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
2 % |
12 |
21 |
213 |
101 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
2 % |
12 |
21 |
214 |
101 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
3 % |
12 |
7 |
71 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
3 % |
12 |
7 |
72 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
3 % |
12 |
7 |
73 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
3 % |
12 |
7 |
74 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
3 % |
12 |
8 |
81 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
3 % |
12 |
8 |
82 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
3 % |
12 |
8 |
83 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
3 % |
12 |
8 |
84 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Cecum, Goblet Cell |
3 % |
12 |
9 |
92 |
101 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
1 % |
12 |
2 |
24 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
1 % |
12 |
3 |
31 |
101 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
1 % |
12 |
3 |
34 |
101 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
2 % |
12 |
19 |
191 |
100 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
2 % |
12 |
19 |
193 |
100 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
2 % |
12 |
20 |
201 |
100 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
2 % |
12 |
20 |
202 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
2 % |
12 |
20 |
203 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
2 % |
12 |
20 |
204 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
2 % |
12 |
21 |
211 |
101 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
2 % |
12 |
21 |
213 |
101 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
2 % |
12 |
21 |
214 |
101 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
3 % |
12 |
7 |
71 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
3 % |
12 |
7 |
72 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
3 % |
12 |
7 |
73 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
3 % |
12 |
7 |
74 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
3 % |
12 |
8 |
81 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
3 % |
12 |
8 |
82 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
3 % |
12 |
8 |
83 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
3 % |
12 |
8 |
84 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
3 % |
12 |
9 |
91 |
101 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
3 % |
12 |
9 |
92 |
101 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon, Goblet Cell |
3 % |
12 |
9 |
93 |
101 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Rectum, Goblet Cell |
3 % |
12 |
7 |
72 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Rectum, Goblet Cell |
3 % |
12 |
7 |
73 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Rectum, Goblet Cell |
3 % |
12 |
7 |
74 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Rectum, Goblet Cell |
3 % |
12 |
8 |
82 |
100 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
3 % |
12 |
9 |
91 |
101 |
1 |
Mixed Cell Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
12 |
13 |
132 |
100 |
1 |
Tension Lipidosis |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
2 % |
12 |
20 |
204 |
100 |
1 |
Tension Lipidosis |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
|
Vehicle Control |
12 |
14 |
143 |
100 |
1 |
Accessory Adrenal Cortical Nodule |
|
Terminal Sacrifice |
Genital System |
Preputial Gland |
Duct |
Vehicle Control |
12 |
13 |
132 |
100 |
1 |
Dilatation |
Moderate |
Terminal Sacrifice |
Genital System |
Preputial Gland |
Duct |
Vehicle Control |
12 |
13 |
134 |
100 |
1 |
Dilatation |
Moderate |
Terminal Sacrifice |
Genital System |
Preputial Gland |
Duct |
Vehicle Control |
12 |
14 |
142 |
100 |
1 |
Dilatation |
Mild |
Terminal Sacrifice |
Genital System |
Preputial Gland |
Duct |
Vehicle Control |
12 |
14 |
143 |
100 |
1 |
Dilatation |
Mild |
Terminal Sacrifice |
Genital System |
Preputial Gland |
Duct |
Vehicle Control |
12 |
14 |
144 |
100 |
1 |
Dilatation |
Marked |
Terminal Sacrifice |
Genital System |
Preputial Gland |
Duct |
Vehicle Control |
12 |
15 |
152 |
101 |
1 |
Dilatation |
Moderate |
Terminal Sacrifice |
Genital System |
Preputial Gland |
Duct |
Vehicle Control |
12 |
15 |
154 |
101 |
1 |
Dilatation |
Marked |
Terminal Sacrifice |
Genital System |
Preputial Gland |
Duct |
1 % |
4 |
2 |
24 |
100 |
1 |
Dilatation |
Mild |
Terminal Sacrifice |
Genital System |
Preputial Gland |
Duct |
1 % |
4 |
3 |
31 |
101 |
1 |
Dilatation |
Mild |
Terminal Sacrifice |
Genital System |
Preputial Gland |
Duct |
1 % |
4 |
3 |
33 |
101 |
1 |
Dilatation |
Mild |
Terminal Sacrifice |
Genital System |
Preputial Gland |
Duct |
1 % |
4 |
3 |
34 |
101 |
1 |
Dilatation |
Moderate |
Terminal Sacrifice |
Genital System |
Preputial Gland |
Duct |
2 % |
6 |
19 |
191 |
100 |
1 |
Dilatation |
Moderate |
Terminal Sacrifice |
Genital System |
Preputial Gland |
Duct |
2 % |
6 |
19 |
192 |
100 |
1 |
Dilatation |
Moderate |
Terminal Sacrifice |
Genital System |
Preputial Gland |
Duct |
2 % |
6 |
20 |
202 |
100 |
1 |
Dilatation |
Moderate |
Terminal Sacrifice |
Genital System |
Preputial Gland |
Duct |
2 % |
6 |
20 |
204 |
100 |
1 |
Dilatation |
Marked |
Terminal Sacrifice |
Genital System |
Preputial Gland |
Duct |
2 % |
6 |
21 |
211 |
101 |
1 |
Dilatation |
Mild |
Terminal Sacrifice |
Genital System |
Preputial Gland |
Duct |
2 % |
6 |
21 |
214 |
101 |
1 |
Dilatation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
Vehicle Control |
12 |
13 |
134 |
100 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
Vehicle Control |
12 |
15 |
151 |
101 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
Vehicle Control |
12 |
15 |
152 |
101 |
1 |
Hyperplasia |
Minimal, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
Vehicle Control |
12 |
15 |
153 |
101 |
1 |
Hyperplasia |
Moderate, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
3 % |
12 |
7 |
72 |
100 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
3 % |
12 |
7 |
73 |
100 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
3 % |
12 |
8 |
81 |
100 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
3 % |
12 |
8 |
84 |
100 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
3 % |
12 |
9 |
91 |
101 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
3 % |
12 |
9 |
92 |
101 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
3 % |
12 |
9 |
93 |
101 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
12 |
15 |
151 |
101 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
12 |
15 |
152 |
101 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
12 |
15 |
153 |
101 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
12 |
15 |
154 |
101 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
1 % |
12 |
1 |
11 |
100 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
1 % |
12 |
3 |
31 |
101 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
2 % |
12 |
21 |
211 |
101 |
1 |
Hematopoietic Cell Proliferation |
Moderate |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
2 % |
12 |
21 |
212 |
101 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
3 % |
12 |
8 |
83 |
100 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
3 % |
12 |
9 |
92 |
101 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
3 % |
12 |
9 |
93 |
101 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
3 % |
12 |
9 |
94 |
101 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
1 % |
12 |
3 |
33 |
101 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
2 % |
12 |
20 |
201 |
100 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Integumentary System |
Skin |
Epidermis |
Vehicle Control |
12 |
14 |
144 |
100 |
1 |
Inflammation |
Minimal, Suppurative |
Terminal Sacrifice |
Urinary System |
Kidney |
|
1 % |
12 |
3 |
31 |
101 |
1 |
Infiltration Cellular |
Minimal, Lymphoid |
Terminal Sacrifice |
Urinary System |
Kidney |
|
2 % |
12 |
21 |
211 |
101 |
1 |
Infiltration Cellular |
Minimal, Lymphoid |
Terminal Sacrifice |
Urinary System |
Urinary Bladder |
|
Vehicle Control |
12 |
14 |
143 |
100 |
1 |
Dilatation |
Marked |
Terminal Sacrifice |
Urinary System |
Urinary Bladder |
|
Vehicle Control |
12 |
15 |
151 |
101 |
1 |
Dilatation |
Marked |
Terminal Sacrifice |
Urinary System |
Urinary Bladder |
|
3 % |
12 |
8 |
81 |
100 |
1 |
Dilatation |
Marked |
Terminal Sacrifice |
Urinary System |
Urinary Bladder |
|
3 % |
12 |
8 |
82 |
100 |
1 |
Dilatation |
Marked |
Terminal Sacrifice |