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Chemical Name: | Water Disinfection Model (Bromodichloromethane) |
---|---|
CASRN: | ="75-27-4" |
Study Number: | C97013E |
Study Length (Year Completed): | 26 Weeks (N/A) |
Exposure Route: | WATER |
TDMS Number: | 9701304.ss |
Sex: | Male |
Strain and Species: | P53 +/- (C57BL/6) Mice |
Hematology Individual Animal Data | |||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Measurement Time | Animal Number | Dose Group (mg/L) | Control Code | Erythrcyt (million/uL) | Hgb (g/dL) | HCT (Automated) (%) | MCV (fL) | MCH (pg) | MCHC (g/dL) | Retics (million/uL) | Platelet (1000/mL) | Leukocytes (1000/mL) | Seg Neut (1000/mL) | Band Neut (1000/mL) | Lymph (1000/mL) | Mono (1000/mL) | EOS (1000/mL) | Basophils (1000/mL) | NRBC (1000/uL) |
Day 184 | 0201 | 0 | V | 10.1 | 15.3 | 47.2 | 46.6 | 15.1 | 32.4 | 60600 | 1003 | 3.9 | 1404 | 0 | 2457 | 39 | 0 | 0 | 0 |
Day 184 | 0202 | 0 | V | 10.5 | 15.3 | 46.7 | 44.7 | 14.6 | 32.8 | 210000 | 932 | 6.7 | 1340 | 0 | 5226 | 0 | 134 | 0 | 0 |
Day 184 | 0203 | 0 | V | 10.6 | 15.6 | 48.2 | 45.6 | 14.7 | 32.3 | 95400 | 846 | 4.4 | 792 | 0 | 3520 | 44 | 44 | 0 | 0 |
Day 184 | 0204 | 0 | V | 10.5 | 15.5 | 47.8 | 45.4 | 14.7 | 32.5 | 84000 | 816 | 6.7 | 871 | 0 | 5762 | 0 | 67 | 0 | 0 |
Day 184 | 0205 | 0 | V | 11.2 | 15.9 | 48.7 | 43.6 | 14.3 | 32.7 | 89600 | 928 | 6.0 | 840 | 0 | 5040 | 0 | 120 | 0 | 0 |
Day 184 | 0206 | 0 | V | 10.6 | 15.9 | 48.9 | 46.0 | 14.9 | 32.4 | 116600 | 1008 | 6.0 | 1140 | 0 | 4800 | 60 | 0 | 0 | 0 |
Day 184 | 0207 | 0 | V | 10.4 | 15.2 | 47.1 | 45.4 | 14.7 | 32.3 | 52000 | 869 | 5.6 | 784 | 0 | 4760 | 56 | 0 | 0 | 0 |
Day 184 | 0208 | 0 | V | 10.3 | 14.9 | 45.7 | 44.5 | 14.5 | 32.6 | 175100 | 893 | 1.5 | 240 | 0 | 1245 | 0 | 15 | 0 | 0 |
Day 184 | 0209 | 0 | V | 9.9 | 14.7 | 45.4 | 45.8 | 14.8 | 32.3 | 79440 | 898 | 2.3 | 529 | 0 | 1725 | 0 | 46 | 0 | 0 |
Day 184 | 0210 | 0 | V | 10.8 | 16.0 | 49.1 | 45.4 | 14.7 | 32.5 | 97200 | 874 | 7.9 | 1027 | 0 | 6715 | 79 | 79 | 0 | 0 |
Day 184 | 0211 | 0 | V | 10.4 | 15.2 | 46.8 | 45.2 | 14.6 | 32.4 | 52000 | 907 | 5.1 | 969 | 0 | 4080 | 0 | 51 | 0 | 0 |
Day 184 | 0212 | 0 | V | 11.0 | 16.0 | 49.2 | 44.8 | 14.5 | 32.5 | 55000 | 995 | 7.1 | 1278 | 0 | 5751 | 0 | 71 | 0 | 0 |
Day 184 | 0213 | 0 | V | 11.0 | 15.8 | 48.5 | 44.0 | 14.3 | 32.6 | 44000 | 870 | 2.8 | 504 | 0 | 2268 | 0 | 28 | 0 | 0 |
Day 184 | 0214 | 0 | V | 11.1 | 15.8 | 48.6 | 43.8 | 14.2 | 32.5 | 33300 | 928 | 5.6 | 840 | 0 | 4592 | 0 | 168 | 0 | 0 |
Day 184 | 0215 | 0 | V | 10.6 | 15.8 | 48.1 | 45.3 | 14.9 | 32.9 | 106000 | 911 | 6.8 | 1088 | 0 | 5576 | 0 | 136 | 0 | 0 |
Day 184 | 0216 | 175 | 10.9 | 16.0 | 49.1 | 45.2 | 14.8 | 32.7 | 43600 | 891 | 7.7 | 1001 | 0 | 6468 | 77 | 154 | 0 | 0 | |
Day 184 | 0218 | 175 | 11.0 | 15.8 | 49.8 | 45.2 | 14.4 | 31.8 | 44000 | 815 | 4.4 | 924 | 0 | 3432 | 0 | 44 | 0 | 0 | |
Day 184 | 0219 | 175 | 10.1 | 15.0 | 46.6 | 46.0 | 14.8 | 32.2 | 80800 | 909 | 5.6 | 1120 | 0 | 4424 | 0 | 56 | 0 | 0 | |
Day 184 | 0220 | 175 | 10.6 | 15.3 | 47.3 | 44.8 | 14.5 | 32.3 | 95400 | 930 | 5.9 | 767 | 0 | 4956 | 0 | 177 | 0 | 0 | |
Day 184 | 0221 | 175 | 10.3 | 15.3 | 47.0 | 45.4 | 14.8 | 32.6 | 144200 | 893 | 5.0 | 900 | 0 | 3950 | 50 | 100 | 0 | 0 | |
Day 184 | 0222 | 175 | 10.7 | 15.6 | 48.7 | 45.5 | 14.6 | 32.0 | 85600 | 980 | 5.5 | 825 | 0 | 4620 | 0 | 55 | 0 | 0 | |
Day 184 | 0223 | 175 | 10.6 | 15.5 | 48.3 | 45.5 | 14.6 | 32.0 | 190800 | 884 | 6.3 | 945 | 0 | 5166 | 0 | 189 | 0 | 0 | |
Day 184 | 0224 | 175 | 10.8 | 16.1 | 48.9 | 45.2 | 14.8 | 32.8 | 54000 | 875 | 6.8 | 1496 | 0 | 5236 | 68 | 0 | 0 | 0 | |
Day 184 | 0225 | 175 | 10.2 | 15.0 | 46.6 | 45.5 | 14.7 | 32.3 | 91800 | 792 | 5.1 | 1071 | 0 | 3978 | 0 | 51 | 0 | 0 | |
Day 184 | 0226 | 175 | 10.4 | 15.2 | 47.2 | 45.5 | 14.6 | 32.2 | 166400 | 961 | 4.2 | 546 | 0 | 3612 | 0 | 42 | 0 | 0 | |
Day 184 | 0227 | 175 | 10.3 | 15.0 | 45.9 | 44.5 | 14.5 | 32.6 | 51500 | 930 | 1.5 | 330 | 0 | 1125 | 15 | 30 | 0 | 0 | |
Day 184 | 0228 | 175 | 10.3 | 15.2 | 46.1 | 44.7 | 14.7 | 32.9 | 30900 | 967 | 4.9 | 882 | 0 | 3920 | 0 | 98 | 0 | 0 | |
Day 184 | 0229 | 175 | 10.3 | 15.3 | 46.9 | 45.3 | 14.8 | 32.7 | 72100 | 884 | 4.8 | 576 | 0 | 4080 | 0 | 144 | 0 | 0 | |
Day 184 | 0230 | 175 | 10.3 | 15.4 | 46.7 | 45.4 | 14.9 | 32.9 | 51500 | 982 | 3.3 | 825 | 0 | 2409 | 33 | 33 | 0 | 0 | |
Day 184 | 0231 | 350 | 10.5 | 15.2 | 47.0 | 44.9 | 14.5 | 32.3 | 126000 | 877 | 5.1 | 663 | 0 | 4335 | 51 | 51 | 0 | 0 | |
Day 184 | 0232 | 350 | 10.2 | 15.0 | 46.5 | 45.7 | 14.7 | 32.2 | 40800 | 931 | 7.1 | 710 | 0 | 6106 | 142 | 142 | 0 | 0 | |
Day 184 | 0233 | 350 | 10.1 | 14.8 | 46.8 | 46.1 | 14.6 | 31.6 | 181800 | 938 | 3.3 | 792 | 0 | 2442 | 0 | 66 | 0 | 0 | |
Day 184 | 0234 | 350 | 10.4 | 15.1 | 46.9 | 44.9 | 14.5 | 32.3 | 135200 | 854 | 5.0 | 650 | 0 | 4200 | 50 | 100 | 0 | 0 | |
Day 184 | 0235 | 350 | 10.3 | 14.7 | 46.4 | 44.9 | 14.2 | 31.6 | 82400 | 1021 | 5.0 | 1000 | 0 | 3950 | 0 | 50 | 0 | 0 | |
Day 184 | 0236 | 350 | 10.7 | 15.5 | 48.9 | 45.7 | 14.5 | 31.7 | 267500 | 791 | 5.4 | 972 | 0 | 4374 | 0 | 54 | 0 | 0 | |
Day 184 | 0237 | 350 | 10.8 | 15.2 | 46.6 | 43.0 | 14.0 | 32.6 | 108000 | 803 | 7.7 | 616 | 0 | 7007 | 0 | 77 | 0 | 0 | |
Day 184 | 0238 | 350 | 10.6 | 14.9 | 46.3 | 43.7 | 14.1 | 32.2 | 127200 | 965 | 5.8 | 1044 | 0 | 4698 | 0 | 58 | 0 | 0 | |
Day 184 | 0239 | 350 | 10.7 | 16.0 | 47.9 | 44.7 | 14.9 | 33.4 | 85600 | 831 | 6.0 | 780 | 0 | 5220 | 0 | 0 | 0 | 0 | |
Day 184 | 0240 | 350 | 10.7 | 15.2 | 47.1 | 44.3 | 14.2 | 32.2 | 42800 | 916 | 4.9 | 882 | 0 | 3969 | 0 | 49 | 0 | 0 | |
Day 184 | 0241 | 350 | 10.3 | 15.1 | 48.4 | 47.0 | 14.7 | 31.3 | 113300 | 917 | 3.3 | 726 | 0 | 2574 | 0 | 0 | 0 | 0 | |
Day 184 | 0242 | 350 | 11.0 | 15.6 | 48.0 | 43.6 | 14.2 | 32.5 | 88000 | 1028 | 3.7 | 1369 | 0 | 2294 | 37 | 0 | 0 | 0 | |
Day 184 | 0243 | 350 | 11.3 | 15.7 | 48.6 | 43.2 | 13.9 | 32.2 | 33900 | 851 | 4.2 | 546 | 0 | 3570 | 0 | 84 | 0 | 0 | |
Day 184 | 0244 | 350 | 10.3 | 15.4 | 47.9 | 46.3 | 14.9 | 32.1 | 103000 | 958 | 4.0 | 800 | 0 | 3160 | 0 | 40 | 0 | 0 | |
Day 184 | 0245 | 350 | 10.9 | 15.9 | 49.5 | 45.4 | 14.6 | 32.2 | 76300 | 799 | 4.6 | 598 | 0 | 4002 | 0 | 0 | 0 | 0 | |
Day 184 | 0246 | 700 | 10.4 | 15.0 | 45.4 | 43.7 | 14.4 | 33.0 | 114400 | 1131 | 4.6 | 644 | 0 | 3956 | 0 | 0 | 0 | 0 | |
Day 184 | 0247 | 700 | 10.0 | 14.4 | 43.4 | 43.3 | 14.4 | 33.1 | 110000 | 1116 | 4.4 | 1232 | 0 | 3080 | 0 | 88 | 0 | 0 | |
Day 184 | 0248 | 700 | 10.3 | 14.5 | 45.0 | 43.5 | 14.1 | 32.3 | 133900 | 1062 | 5.9 | 1003 | 0 | 4602 | 0 | 295 | 0 | 0 | |
Day 184 | 0249 | 700 | 10.6 | 15.3 | 46.8 | 44.1 | 14.4 | 32.6 | 201400 | 977 | 2.6 | 520 | 0 | 2028 | 0 | 52 | 0 | 0 | |
Day 184 | 0250 | 700 | 10.1 | 14.5 | 45.9 | 45.5 | 14.4 | 31.6 | 60600 | 1168 | 1.3 | 221 | 0 | 1079 | 0 | 0 | 0 | 0 | |
Day 184 | 0251 | 700 | 10.3 | 15.0 | 46.1 | 44.6 | 14.5 | 32.6 | 61800 | 898 | 5.5 | 880 | 0 | 4510 | 0 | 110 | 0 | 0 | |
Day 184 | 0252 | 700 | 10.6 | 15.1 | 47.6 | 44.8 | 14.2 | 31.7 | 169600 | 990 | 5.8 | 696 | 0 | 5046 | 58 | 0 | 0 | 0 | |
Day 184 | 0253 | 700 | 10.0 | 13.8 | 42.2 | 42.4 | 13.8 | 32.6 | 199000 | 964 | 7.9 | 1027 | 0 | 6636 | 0 | 237 | 0 | 0 | |
Day 184 | 0254 | 700 | 10.6 | 15.2 | 46.5 | 44.0 | 14.4 | 32.7 | 275600 | 895 | 7.0 | 980 | 0 | 5950 | 0 | 70 | 0 | 0 | |
Day 184 | 0255 | 700 | 10.6 | 15.1 | 47.5 | 44.6 | 14.2 | 31.8 | 106000 | 988 | 3.5 | 630 | 0 | 2800 | 0 | 70 | 0 | 0 | |
Day 184 | 0256 | 700 | 10.5 | 15.1 | 46.2 | 44.0 | 14.4 | 32.7 | 126000 | 831 | 6.2 | 1364 | 0 | 4650 | 0 | 186 | 0 | 0 | |
Day 184 | 0257 | 700 | 11.1 | 16.1 | 49.7 | 44.8 | 14.5 | 32.3 | 77700 | 662 | 5.9 | 708 | 0 | 5074 | 0 | 118 | 0 | 0 | |
Day 184 | 0258 | 700 | 10.9 | 15.9 | 47.9 | 43.9 | 14.6 | 33.2 | 98100 | 1071 | 7.4 | 1850 | 0 | 5328 | 74 | 148 | 0 | 0 | |
Day 184 | 0259 | 700 | 10.1 | 14.5 | 45.8 | 45.3 | 14.3 | 31.7 | 161600 | 1384 | 5.8 | 1102 | 0 | 4698 | 0 | 0 | 0 | 0 | |
Day 184 | 0260 | 700 | 10.4 | 15.1 | 47.8 | 45.8 | 14.5 | 31.6 | 145600 | 838 | 1.7 | 459 | 0 | 1224 | 0 | 17 | 0 | 0 | |
Abbreviations: | |||||||||||||||||||
NA: Not Available, V: Vehicle Control, Erythrcyt: Red Blood Cell Count, Hgb: Hemoglobin, HCT (Automated): Hematocrit, MCV: Mean Corpuscular Volume, MCH: Mean Cell Hemoglobin, MCHC: Mean Cell Hemoglobin Concentration, Retics: Reticulocyte Count, Platelet: Platelet Count, Leukocytes: White Blood Cell Count, Seg Neut: Segmented Neutrophil Count, Band Neut: Band Neutrophil Count, Lymph: Lymphocyte Count, Mono: Monocyte Count, EOS: Eosinophil Count, Basophils: Basophil Count, NRBC: Nucleated Rbc Count |