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Chemical Name: | Cumene |
---|---|
CASRN: | ="98-82-8" |
Study Number: | C96011 |
Study Length (Year Completed): | 13 Weeks (N/A) |
Exposure Route: | INHAL |
TDMS Number: | 9601103.fixtime |
Sex: | Female |
Strain and Species: | Fischer 344 Rats |
Clinical Chemistry Individual Animal Data | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Measurement Time | Animal Number | Dose Group (ppm) | Control Code | BUN (mg_dL) | Creat (U per L) | TP (g_dL) | ALB (g_dL) | Globulin (g per dL) | A/G Ratio | Creat Kinase (IU_L) | ALT (IU_L) | SDH (IU_L) | ALP (IU_L) | TBA (umol per g) |
Day 3 | 0111 | 0 | U | 7.0 | 0.70 | 5.4 | 3.4 | 2.0 | 1.7 | 298.0 | 50.0 | 13.0 | 632 | 26.0 |
Day 3 | 0112 | 0 | U | 10.0 | 0.70 | 5.7 | 3.6 | 2.1 | 1.7 | 250.0 | 46.0 | 13.0 | 602 | 31.1 |
Day 3 | 0113 | 0 | U | 11.0 | 0.70 | 5.4 | 3.2 | 2.2 | 1.5 | 368.0 | 47.0 | 12.0 | 614 | 31.8 |
Day 3 | 0114 | 0 | U | 10.0 | 0.70 | 5.7 | 3.6 | 2.1 | 1.7 | 186.0 | 52.0 | 12.0 | 666 | 34.2 |
Day 3 | 0115 | 0 | U | 9.0 | 0.60 | 6.0 | 4.1 | 1.9 | 2.2 | 320.0 | 50.0 | 17.0 | 602 | 21.9 |
Day 3 | 0116 | 0 | U | 8.0 | 0.70 | 5.7 | 3.7 | 2.0 | 1.9 | 199.0 | 44.0 | 14.0 | 604 | 25.4 |
Day 3 | 0117 | 0 | U | 11.0 | 0.80 | 5.9 | 3.7 | 2.2 | 1.7 | 406.0 | 49.0 | 12.0 | 612 | 24.4 |
Day 3 | 0118 | 0 | U | 9.0 | 0.60 | 5.8 | 3.5 | 2.3 | 1.5 | 373.0 | 54.0 | 12.0 | 673 | 28.1 |
Day 3 | 0119 | 0 | U | 6.0 | 0.70 | 5.5 | 3.4 | 2.1 | 1.6 | 402.0 | 55.0 | 11.0 | 786 | 22.5 |
Day 3 | 0120 | 0 | U | 9.0 | 0.70 | 5.8 | 3.4 | 2.4 | 1.4 | 228.0 | 53.0 | 14.0 | 627 | 26.2 |
Day 3 | 0311 | 62.5 | 7.0 | 0.70 | 5.6 | 3.5 | 2.1 | 1.7 | 170.0 | 43.0 | 13.0 | 561 | 28.6 | |
Day 3 | 0312 | 62.5 | 11.0 | 0.70 | 5.5 | 3.6 | 1.9 | 1.9 | 197.0 | 52.0 | 12.0 | 628 | 42.8 | |
Day 3 | 0313 | 62.5 | 8.0 | 0.60 | 5.8 | 3.7 | 2.1 | 1.8 | 394.0 | 49.0 | 15.0 | 634 | 23.4 | |
Day 3 | 0314 | 62.5 | 7.0 | 0.70 | 5.6 | 3.3 | 2.3 | 1.4 | 1004.0 | 45.0 | 10.0 | 591 | 28.3 | |
Day 3 | 0315 | 62.5 | 8.0 | 0.70 | 5.6 | 3.5 | 2.1 | 1.7 | 433.0 | 60.0 | 14.0 | 756 | 36.8 | |
Day 3 | 0316 | 62.5 | 10.0 | 0.70 | 5.8 | 3.7 | 2.1 | 1.8 | 297.0 | 60.0 | 13.0 | 667 | 34.3 | |
Day 3 | 0317 | 62.5 | 8.0 | 0.60 | 6.0 | 4.0 | 2.0 | 2.0 | 261.0 | 44.0 | 12.0 | 519 | 27.4 | |
Day 3 | 0318 | 62.5 | 11.0 | 0.70 | 5.6 | 3.7 | 1.9 | 1.9 | 329.0 | 51.0 | 12.0 | 607 | 39.2 | |
Day 3 | 0319 | 62.5 | 7.0 | 0.70 | 5.5 | 3.5 | 2.0 | 1.8 | 270.0 | 55.0 | 12.0 | 669 | 34.1 | |
Day 3 | 0320 | 62.5 | 7.0 | 0.80 | 5.5 | 3.5 | 2.0 | 1.8 | 264.0 | 53.0 | 13.0 | 725 | 31.5 | |
Day 3 | 0511 | 125 | 8.0 | 0.60 | 5.7 | 3.7 | 2.0 | 1.9 | 369.0 | 52.0 | 13.0 | 562 | 34.3 | |
Day 3 | 0512 | 125 | 6.0 | 0.60 | 5.7 | 3.7 | 2.0 | 1.9 | 307.0 | 40.0 | 15.0 | 588 | 28.2 | |
Day 3 | 0513 | 125 | 7.0 | 0.70 | 5.5 | 3.4 | 2.1 | 1.6 | 189.0 | 40.0 | 12.0 | 606 | 23.0 | |
Day 3 | 0514 | 125 | 7.0 | 0.70 | 5.4 | 3.6 | 1.8 | 2.0 | 305.0 | 52.0 | 14.0 | 630 | 41.8 | |
Day 3 | 0515 | 125 | 8.0 | 0.60 | 5.5 | 3.5 | 2.0 | 1.8 | 436.0 | 56.0 | 13.0 | 779 | 40.3 | |
Day 3 | 0516 | 125 | 8.0 | 0.60 | 5.6 | 3.3 | 2.3 | 1.4 | 296.0 | 45.0 | 12.0 | 593 | 38.9 | |
Day 3 | 0517 | 125 | 8.0 | 0.70 | 5.5 | 3.5 | 2.0 | 1.8 | 246.0 | 57.0 | 12.0 | 608 | 30.1 | |
Day 3 | 0518 | 125 | 8.0 | 0.60 | 5.5 | 3.4 | 2.1 | 1.6 | 329.0 | 51.0 | 12.0 | 633 | 35.6 | |
Day 3 | 0519 | 125 | 9.0 | 0.60 | 5.8 | 3.7 | 2.1 | 1.8 | 463.0 | 41.0 | 14.0 | 595 | 36.2 | |
Day 3 | 0520 | 125 | 8.0 | 0.70 | 5.7 | 3.9 | 1.8 | 2.2 | 320.0 | 48.0 | 13.0 | 590 | 35.7 | |
Day 3 | 0711 | 250 | 10.0 | 0.70 | 5.6 | 3.3 | 2.3 | 1.4 | 242.0 | 47.0 | 13.0 | 608 | 44.2 | |
Day 3 | 0712 | 250 | 6.0 | 0.60 | 5.2 | 3.4 | 1.8 | 1.9 | 473.0 | 53.0 | 13.0 | 648 | 37.1 | |
Day 3 | 0713 | 250 | 6.0 | 0.60 | 5.7 | 3.3 | 2.4 | 1.4 | 308.0 | 46.0 | 13.0 | 562 | 33.7 | |
Day 3 | 0714 | 250 | 9.0 | 0.60 | 5.4 | 3.4 | 2.0 | 1.7 | 249.0 | 56.0 | 13.0 | 628 | 48.5 | |
Day 3 | 0715 | 250 | 9.0 | 0.60 | 5.3 | 3.4 | 1.9 | 1.8 | 489.0 | 52.0 | 12.0 | 584 | 42.5 | |
Day 3 | 0716 | 250 | 8.0 | 0.60 | 5.4 | 3.4 | 2.0 | 1.7 | 188.0 | 52.0 | 12.0 | 652 | 36.2 | |
Day 3 | 0717 | 250 | 5.0 | 0.60 | 5.7 | 3.7 | 2.0 | 1.9 | 264.0 | 47.0 | 13.0 | 656 | 29.6 | |
Day 3 | 0718 | 250 | 7.0 | 0.70 | 5.5 | 3.6 | 1.9 | 1.9 | 282.0 | 43.0 | 12.0 | 602 | 34.8 | |
Day 3 | 0719 | 250 | 9.0 | 0.60 | 5.8 | 3.7 | 2.1 | 1.8 | 415.0 | 49.0 | 12.0 | 569 | 40.9 | |
Day 3 | 0720 | 250 | 9.0 | 0.60 | 5.8 | 3.7 | 2.1 | 1.8 | 230.0 | 39.0 | 11.0 | 568 | 37.7 | |
Day 3 | 0911 | 500 | 10.0 | 0.60 | 5.7 | 3.5 | 2.2 | 1.6 | 366.0 | 41.0 | 12.0 | 561 | 41.2 | |
Day 3 | 0912 | 500 | 7.0 | 0.70 | 5.7 | 3.5 | 2.2 | 1.6 | 256.0 | 48.0 | 12.0 | 629 | 42.8 | |
Day 3 | 0913 | 500 | 12.0 | 0.70 | 5.7 | 3.8 | 1.9 | 2.0 | 308.0 | 38.0 | 12.0 | 537 | 41.5 | |
Day 3 | 0914 | 500 | 8.0 | 0.70 | 5.3 | 3.4 | 1.9 | 1.8 | 432.0 | 44.0 | 12.0 | 541 | 45.3 | |
Day 3 | 0915 | 500 | 9.0 | 0.70 | 5.6 | 3.5 | 2.1 | 1.7 | 368.0 | 45.0 | 14.0 | 523 | 39.3 | |
Day 3 | 0916 | 500 | 8.0 | 0.60 | 5.3 | 3.5 | 1.8 | 1.9 | 438.0 | 54.0 | 12.0 | 661 | 46.8 | |
Day 3 | 0917 | 500 | 8.0 | 0.60 | 5.4 | 3.6 | 1.8 | 2.0 | 330.0 | 49.0 | 12.0 | 550 | 45.5 | |
Day 3 | 0918 | 500 | 9.0 | 0.70 | 5.8 | 3.7 | 2.1 | 1.8 | 358.0 | 48.0 | 12.0 | 620 | 39.3 | |
Day 3 | 0919 | 500 | 9.0 | 0.60 | 5.7 | 3.5 | 2.2 | 1.6 | 520.0 | 46.0 | 12.0 | 625 | 40.0 | |
Day 3 | 0920 | 500 | 8.0 | 0.60 | 5.3 | 3.6 | 1.7 | 2.1 | 295.0 | 52.0 | 11.0 | 603 | 43.0 | |
Day 3 | 1111 | 1000 | 9.0 | 0.60 | 5.6 | 3.6 | 2.0 | 1.8 | 189.0 | 40.0 | 12.0 | 442 | 40.0 | |
Day 3 | 1112 | 1000 | 11.0 | 0.60 | 5.6 | 3.9 | 1.7 | 2.3 | 230.0 | 33.0 | 13.0 | 432 | 33.0 | |
Day 3 | 1113 | 1000 | 11.0 | 0.60 | 5.6 | 3.8 | 1.8 | 2.1 | 315.0 | 43.0 | 11.0 | 443 | 44.2 | |
Day 3 | 1114 | 1000 | 9.0 | 0.60 | 5.6 | 3.5 | 2.1 | 1.7 | 725.0 | 47.0 | 11.0 | 481 | 39.9 | |
Day 3 | 1115 | 1000 | 11.0 | 0.70 | 5.7 | 3.4 | 2.3 | 1.5 | 281.0 | 40.0 | 12.0 | 505 | 35.5 | |
Day 3 | 1116 | 1000 | 13.0 | 0.60 | 6.0 | 3.6 | 2.4 | 1.5 | 412.0 | 47.0 | 12.0 | 468 | 46.9 | |
Day 3 | 1117 | 1000 | 9.0 | 0.60 | 5.8 | 3.7 | 2.1 | 1.8 | 237.0 | 43.0 | 13.0 | 504 | 31.6 | |
Day 3 | 1118 | 1000 | 13.0 | 0.70 | 5.7 | 3.7 | 2.0 | 1.9 | 253.0 | 45.0 | 13.0 | 485 | 41.0 | |
Day 3 | 1119 | 1000 | 8.0 | 0.60 | 5.8 | 3.9 | 1.9 | 2.1 | 269.0 | 37.0 | 12.0 | 457 | 31.1 | |
Day 3 | 1120 | 1000 | 11.0 | 0.60 | 5.6 | 3.7 | 1.9 | 1.9 | 287.0 | 49.0 | 10.0 | 519 | 36.5 | |
Day 23 | 0111 | 0 | U | 11.0 | 0.70 | 5.8 | 3.6 | 2.2 | 1.6 | 180.0 | 34.0 | 10.0 | 375 | 23.9 |
Day 23 | 0112 | 0 | U | 12.0 | 0.80 | 6.2 | 3.9 | 2.3 | 1.7 | 296.0 | 37.0 | 13.0 | 368 | 23.0 |
Day 23 | 0113 | 0 | U | 14.0 | 0.70 | 6.3 | 3.8 | 2.5 | 1.5 | 294.0 | 40.0 | 13.0 | 357 | 20.0 |
Day 23 | 0114 | 0 | U | 12.0 | 0.70 | 5.9 | 3.6 | 2.3 | 1.6 | 160.0 | 40.0 | 12.0 | 410 | 27.3 |
Day 23 | 0115 | 0 | U | 14.0 | 0.70 | 6.2 | 3.9 | 2.3 | 1.7 | 267.0 | 36.0 | 10.0 | 387 | 22.2 |
Day 23 | 0116 | 0 | U | 10.0 | 0.70 | 6.4 | 3.9 | 2.5 | 1.6 | 249.0 | 33.0 | 14.0 | 354 | 22.3 |
Day 23 | 0117 | 0 | U | 11.0 | 0.70 | 5.8 | 3.7 | 2.1 | 1.8 | 431.0 | 37.0 | 10.0 | 376 | 23.5 |
Day 23 | 0118 | 0 | U | 14.0 | 0.70 | 5.9 | 3.6 | 2.3 | 1.6 | 142.0 | 39.0 | 10.0 | 357 | 21.2 |
Day 23 | 0119 | 0 | U | 16.0 | 0.70 | 6.6 | 3.9 | 2.7 | 1.4 | 147.0 | 31.0 | 13.0 | 352 | 21.1 |
Day 23 | 0120 | 0 | U | 15.0 | 0.80 | 6.2 | 3.8 | 2.4 | 1.6 | 254.0 | 41.0 | 12.0 | 383 | 25.6 |
Day 23 | 0311 | 62.5 | 12.0 | 0.70 | 6.2 | 3.9 | 2.3 | 1.7 | 238.0 | 44.0 | 12.0 | 403 | 30.8 | |
Day 23 | 0312 | 62.5 | 14.0 | 0.70 | 6.1 | 3.7 | 2.4 | 1.5 | 303.0 | 40.0 | 9.0 | 413 | 39.0 | |
Day 23 | 0313 | 62.5 | 14.0 | 0.70 | 6.3 | 3.9 | 2.4 | 1.6 | 178.0 | 32.0 | 11.0 | 310 | 24.2 | |
Day 23 | 0314 | 62.5 | 11.0 | 0.70 | 6.1 | 3.8 | 2.3 | 1.7 | 222.0 | 36.0 | 11.0 | 400 | 28.3 | |
Day 23 | 0315 | 62.5 | 12.0 | 0.70 | 6.0 | 3.8 | 2.2 | 1.7 | 193.0 | 37.0 | 11.0 | 398 | 30.2 | |
Day 23 | 0316 | 62.5 | 14.0 | 0.80 | 6.0 | 3.7 | 2.3 | 1.6 | 178.0 | 34.0 | 11.0 | 376 | 26.3 | |
Day 23 | 0317 | 62.5 | 12.0 | 0.70 | 6.1 | 3.6 | 2.5 | 1.4 | 202.0 | 42.0 | 12.0 | 352 | 23.7 | |
Day 23 | 0318 | 62.5 | 10.0 | 0.70 | 6.3 | 3.8 | 2.5 | 1.5 | 179.0 | 33.0 | 11.0 | 420 | 24.3 | |
Day 23 | 0319 | 62.5 | 11.0 | 0.70 | 5.8 | 3.5 | 2.3 | 1.5 | 187.0 | 33.0 | 11.0 | 384 | 23.4 | |
Day 23 | 0320 | 62.5 | 17.0 | 0.70 | 6.2 | 3.9 | 2.3 | 1.7 | 448.0 | 36.0 | 10.0 | 425 | 25.5 | |
Day 23 | 0511 | 125 | 12.0 | 0.70 | 5.9 | 3.7 | 2.2 | 1.7 | 241.0 | 30.0 | 12.0 | 355 | 27.1 | |
Day 23 | 0512 | 125 | 10.0 | 0.70 | 5.9 | 3.7 | 2.2 | 1.7 | 163.0 | 36.0 | 12.0 | 336 | 28.7 | |
Day 23 | 0513 | 125 | 10.0 | 0.70 | 5.9 | 3.7 | 2.2 | 1.7 | 167.0 | 33.0 | 11.0 | 390 | 28.8 | |
Day 23 | 0514 | 125 | 12.0 | 0.70 | 6.2 | 4.0 | 2.2 | 1.8 | 178.0 | 37.0 | 11.0 | 395 | 34.7 | |
Day 23 | 0515 | 125 | 14.0 | 0.70 | 5.8 | 3.5 | 2.3 | 1.5 | 258.0 | 36.0 | 10.0 | 414 | 30.7 | |
Day 23 | 0516 | 125 | 15.0 | 0.70 | 5.8 | 3.6 | 2.2 | 1.6 | 263.0 | 38.0 | 10.0 | 371 | 30.8 | |
Day 23 | 0517 | 125 | 13.0 | 0.70 | 6.2 | 3.9 | 2.3 | 1.7 | 137.0 | 30.0 | 12.0 | 352 | 24.1 | |
Day 23 | 0518 | 125 | 14.0 | 0.70 | 6.0 | 3.7 | 2.3 | 1.6 | 214.0 | 32.0 | 9.0 | 347 | 28.4 | |
Day 23 | 0519 | 125 | 12.0 | 0.70 | 5.9 | 3.6 | 2.3 | 1.6 | 259.0 | 30.0 | 11.0 | 372 | 28.1 | |
Day 23 | 0520 | 125 | 11.0 | 0.70 | 6.1 | 3.7 | 2.4 | 1.5 | 207.0 | 37.0 | 13.0 | 370 | 29.1 | |
Day 23 | 0711 | 250 | 13.0 | 0.70 | 6.2 | 4.0 | 2.2 | 1.8 | 215.0 | 39.0 | 10.0 | 403 | 30.4 | |
Day 23 | 0712 | 250 | 12.0 | 0.70 | 5.9 | 3.7 | 2.2 | 1.7 | 139.0 | 32.0 | 10.0 | 361 | 34.3 | |
Day 23 | 0713 | 250 | 13.0 | 0.80 | 6.3 | 4.1 | 2.2 | 1.9 | 166.0 | 31.0 | 13.0 | 303 | 28.5 | |
Day 23 | 0714 | 250 | 10.0 | 0.70 | 6.2 | 3.8 | 2.4 | 1.6 | 256.0 | 40.0 | 11.0 | 405 | 35.7 | |
Day 23 | 0715 | 250 | 12.0 | 0.70 | 5.9 | 3.8 | 2.1 | 1.8 | 254.0 | 34.0 | 13.0 | 351 | 27.0 | |
Day 23 | 0716 | 250 | 12.0 | 0.70 | 5.8 | 3.6 | 2.2 | 1.6 | 133.0 | 32.0 | 11.0 | 353 | 36.8 | |
Day 23 | 0717 | 250 | 11.0 | 0.70 | 5.9 | 3.7 | 2.2 | 1.7 | 1105.0 a | 34.0 | 12.0 | 367 | 26.6 | |
Day 23 | 0718 | 250 | 13.0 | 0.70 | 6.2 | 4.0 | 2.2 | 1.8 | 155.0 | 29.0 | 12.0 | 355 | 30.2 | |
Day 23 | 0719 | 250 | 13.0 | 0.80 | 6.0 | 3.7 | 2.3 | 1.6 | 154.0 | 39.0 | 12.0 | 372 | 33.6 | |
Day 23 | 0720 | 250 | 12.0 | 0.70 | 6.3 | 4.2 | 2.1 | 2.0 | 232.0 | 35.0 | 11.0 | 349 | 32.0 | |
Day 23 | 0911 | 500 | 12.0 | 0.70 | 6.1 | 3.9 | 2.2 | 1.8 | 142.0 | 34.0 | 10.0 | 330 | 38.9 | |
Day 23 | 0912 | 500 | 10.0 | 0.70 | 6.2 | 3.9 | 2.3 | 1.7 | 279.0 | 37.0 | 11.0 | 335 | 34.0 | |
Day 23 | 0913 | 500 | 14.0 | 0.70 | 6.5 | 3.7 | 2.8 | 1.3 | 197.0 | 33.0 | 11.0 | 369 | 43.8 | |
Day 23 | 0914 | 500 | 13.0 | 0.80 | 5.8 | 3.4 | 2.4 | 1.4 | 334.0 | 36.0 | 11.0 | 365 | 61.6 a | |
Day 23 | 0915 | 500 | 9.0 | 0.70 | 6.2 | 3.7 | 2.5 | 1.5 | 177.0 | 39.0 | 11.0 | 360 | 31.5 | |
Day 23 | 0916 | 500 | 13.0 | 0.80 | 6.3 | 3.8 | 2.5 | 1.5 | 163.0 | 36.0 | 11.0 | 323 | 32.4 | |
Day 23 | 0917 | 500 | 12.0 | 0.80 | 6.0 | 3.8 | 2.2 | 1.7 | 252.0 | 31.0 | 12.0 | 335 | 35.6 | |
Day 23 | 0918 | 500 | 12.0 | 0.70 | 6.4 | 4.0 | 2.4 | 1.7 | 181.0 | 30.0 | 11.0 | 345 | 32.5 | |
Day 23 | 0919 | 500 | 10.0 | 0.70 | 6.1 | 3.8 | 2.3 | 1.7 | 371.0 | 37.0 | 11.0 | 392 | 34.6 | |
Day 23 | 0920 | 500 | 12.0 | 0.70 | 6.0 | 3.6 | 2.4 | 1.5 | 193.0 | 31.0 | 10.0 | 321 | 40.2 | |
Day 23 | 1111 | 1000 | 9.0 | 0.70 | 6.1 | 3.6 | 2.5 | 1.4 | 423.0 | 35.0 | 11.0 | 296 | 69.4 a | |
Day 23 | 1112 | 1000 | 9.0 | 0.70 | 6.1 | 3.8 | 2.3 | 1.7 | 180.0 | 32.0 | 11.0 | 299 | 35.3 | |
Day 23 | 1113 | 1000 | 11.0 | 0.80 | 6.4 | 3.9 | 2.5 | 1.6 | 253.0 | 37.0 | 13.0 | 332 | 38.4 | |
Day 23 | 1114 | 1000 | 12.0 | 0.70 | 6.5 | 4.3 | 2.2 | 2.0 | 206.0 | 37.0 | 13.0 | 339 | 38.1 | |
Day 23 | 1115 | 1000 | 13.0 | 0.70 | 6.1 | 3.7 | 2.4 | 1.5 | 155.0 | 34.0 | 12.0 | 303 | 30.5 | |
Day 23 | 1116 | 1000 | 10.0 | 0.70 | 6.3 | 3.9 | 2.4 | 1.6 | 215.0 | 31.0 | 12.0 | 287 | 35.2 | |
Day 23 | 1117 | 1000 | 12.0 | 0.70 | 6.0 | 3.8 | 2.2 | 1.7 | 275.0 | 32.0 | 11.0 | 335 | 40.1 | |
Day 23 | 1118 | 1000 | 13.0 | 0.70 | 6.0 | 3.5 | 2.5 | 1.4 | 218.0 | 31.0 | 11.0 | 350 | 33.7 | |
Day 23 | 1119 | 1000 | 13.0 | 0.70 | 6.3 | 3.9 | 2.4 | 1.6 | 218.0 | 29.0 | 11.0 | 303 | 29.9 | |
Day 23 | 1120 | 1000 | 10.0 | 0.70 | 6.2 | 3.8 | 2.4 | 1.6 | 306.0 | 33.0 | 11.0 | 343 | 32.9 | |
Day 93 | 0101 | 0 | U | 18.0 | 1.00 | 6.7 | 4.6 | 2.1 | 2.2 | 80.0 | 126.0 | 26.0 | 294 | 26.9 |
Day 93 | 0102 | 0 | U | 11.0 | 0.90 | 6.1 | 3.9 | 2.2 | 1.8 | 161.0 | 66.0 | 18.0 | 256 | 23.5 |
Day 93 | 0103 | 0 | U | 16.0 | 1.00 | 6.9 | 4.0 | 2.9 | 1.4 | 138.0 | 123.0 | 29.0 | 301 | 28.9 |
Day 93 | 0104 | 0 | U | 16.0 | 1.00 | 6.4 | 4.3 | 2.1 | 2.0 | 302.0 | 77.0 | 20.0 | 283 | 39.5 |
Day 93 | 0105 | 0 | U | 15.0 | 1.00 | 6.3 | 3.7 | 2.6 | 1.4 | 201.0 | 76.0 | 23.0 | 304 | 25.9 |
Day 93 | 0106 | 0 | U | 15.0 | 1.00 | 7.0 | 4.2 | 2.8 | 1.5 | 87.0 | 67.0 | 23.0 | 274 | 48.0 |
Day 93 | 0107 | 0 | U | 13.0 | 1.00 | 6.7 | 4.1 | 2.6 | 1.6 | 132.0 | 67.0 | 19.0 | 248 | 22.6 |
Day 93 | 0108 | 0 | U | 12.0 | 0.90 | 6.9 | 4.4 | 2.5 | 1.8 | 174.0 | 62.0 | 19.0 | 230 | 31.6 |
Day 93 | 0109 | 0 | U | 13.0 | 1.00 | 6.7 | 4.3 | 2.4 | 1.8 | 69.0 | 64.0 | 20.0 | 231 | 21.0 |
Day 93 | 0110 | 0 | U | 15.0 | 0.90 | 6.4 | 4.0 | 2.4 | 1.7 | 143.0 | 70.0 | 21.0 | 295 | 28.8 |
Day 93 | 0301 | 62.5 | 13.0 | 1.00 | 6.6 | 4.3 | 2.3 | 1.9 | 115.0 | 64.0 | 19.0 | 306 | 25.7 | |
Day 93 | 0302 | 62.5 | 13.0 | 1.00 | 7.1 | 4.4 | 2.7 | 1.6 | 144.0 | 91.0 | 22.0 | 239 | 22.2 | |
Day 93 | 0303 | 62.5 | 14.0 | 1.00 | 6.4 | 3.9 | 2.5 | 1.6 | 98.0 | 70.0 | 22.0 | 289 | 22.2 | |
Day 93 | 0304 | 62.5 | 16.0 | 1.10 | 6.9 | 4.0 | 2.9 | 1.4 | 92.0 | 68.0 | 22.0 | 274 | 22.8 | |
Day 93 | 0305 | 62.5 | 15.0 | 1.10 | 6.2 | 3.7 | 2.5 | 1.5 | 88.0 | 67.0 | 21.0 | 248 | 22.2 | |
Day 93 | 0306 | 62.5 | 16.0 | 1.10 | 7.1 | 3.9 | 3.2 | 1.2 | 91.0 | 41.0 | 17.0 | 276 | 28.4 | |
Day 93 | 0307 | 62.5 | 15.0 | 1.00 | 6.7 | 3.8 | 2.9 | 1.3 | 101.0 | 46.0 | 17.0 | 287 | 16.2 | |
Day 93 | 0308 | 62.5 | 14.0 | 1.10 | 6.8 | 4.0 | 2.8 | 1.4 | 87.0 | 54.0 | 20.0 | 243 | 28.3 | |
Day 93 | 0309 | 62.5 | 14.0 | 1.00 | 6.6 | 4.0 | 2.6 | 1.5 | 221.0 | 99.0 | 30.0 | 274 | 30.0 | |
Day 93 | 0310 | 62.5 | 15.0 | 1.10 | 6.9 | 4.2 | 2.7 | 1.6 | 195.0 | 44.0 | 16.0 | 310 | 25.2 | |
Day 93 | 0501 | 125 | 14.0 | 1.00 | 7.1 | 4.2 | 2.9 | 1.4 | 88.0 | 70.0 | 19.0 | 258 | 28.5 | |
Day 93 | 0502 | 125 | 13.0 | 0.90 | 6.5 | 4.4 | 2.1 | 2.1 | 99.0 | 88.0 | 20.0 | 267 | 24.7 | |
Day 93 | 0503 | 125 | 12.0 | 1.00 | 6.5 | 4.3 | 2.2 | 2.0 | 97.0 | 51.0 | 18.0 | 239 | 30.8 | |
Day 93 | 0504 | 125 | 14.0 | 1.10 | 6.9 | 4.7 | 2.2 | 2.1 | 106.0 | 78.0 | 21.0 | 301 | 31.1 | |
Day 93 | 0505 | 125 | 16.0 | 1.00 | 7.3 | 4.4 | 2.9 | 1.5 | 147.0 | 54.0 | 18.0 | 269 | 23.1 | |
Day 93 | 0506 | 125 | 15.0 | 1.00 | 6.9 | 4.2 | 2.7 | 1.6 | 77.0 | 54.0 | 21.0 | 304 | 22.2 | |
Day 93 | 0507 | 125 | 14.0 | 1.00 | 7.2 | 4.7 | 2.5 | 1.9 | 84.0 | 67.0 | 18.0 | 285 | 15.7 | |
Day 93 | 0508 | 125 | 16.0 | 1.10 | 6.9 | 4.5 | 2.4 | 1.9 | 211.0 | 55.0 | 19.0 | 265 | 31.8 | |
Day 93 | 0509 | 125 | 17.0 | 1.00 | 6.8 | 3.9 | 2.9 | 1.3 | 112.0 | 42.0 | 16.0 | 176 | 23.7 | |
Day 93 | 0510 | 125 | 15.0 | 1.00 | 6.4 | 3.9 | 2.5 | 1.6 | 176.0 | 72.0 | 20.0 | 251 | 30.0 | |
Day 93 | 0701 | 250 | 13.0 | 1.00 | 6.8 | 4.2 | 2.6 | 1.6 | 128.0 | 55.0 | 16.0 | 250 | 34.3 | |
Day 93 | 0702 | 250 | 15.0 | 1.00 | 7.1 | 4.5 | 2.6 | 1.7 | 89.0 | 60.0 | 18.0 | 222 | 36.2 | |
Day 93 | 0703 | 250 | 15.0 | 1.10 | 7.0 | 3.8 | 3.2 | 1.2 | 109.0 | 51.0 | 21.0 | 250 | 22.0 | |
Day 93 | 0704 | 250 | 14.0 | 1.00 | 6.6 | 3.7 | 2.9 | 1.3 | 158.0 | 55.0 | 20.0 | 295 | 30.8 | |
Day 93 | 0705 | 250 | 17.0 | 1.10 | 7.1 | 4.1 | 3.0 | 1.4 | 202.0 | 74.0 | 21.0 | 274 | 25.4 | |
Day 93 | 0706 | 250 | 15.0 | 1.10 | 6.8 | 4.6 | 2.2 | 2.1 | 129.0 | 38.0 | 20.0 | 270 | 21.1 | |
Day 93 | 0707 | 250 | 15.0 | 1.10 | 6.7 | 4.6 | 2.1 | 2.2 | 118.0 | 40.0 | 16.0 | 301 | 24.1 | |
Day 93 | 0708 | 250 | 16.0 | 1.20 | 6.7 | 4.0 | 2.7 | 1.5 | 256.0 | 64.0 | 20.0 | 261 | 68.1 a | |
Day 93 | 0709 | 250 | 16.0 | 1.10 | 6.8 | 3.7 | 3.1 | 1.2 | 118.0 | 41.0 | 19.0 | 283 | 29.1 | |
Day 93 | 0710 | 250 | 15.0 | 1.00 | 7.0 | 4.7 | 2.3 | 2.0 | 96.0 | 55.0 | 18.0 | 265 | 30.0 | |
Day 93 | 0901 | 500 | 13.0 | 0.90 | 6.6 | 4.3 | 2.3 | 1.9 | 88.0 | 53.0 | 19.0 | 207 | 24.0 | |
Day 93 | 0902 | 500 | 14.0 | 1.00 | 6.9 | 4.6 | 2.3 | 2.0 | 82.0 | 43.0 | 16.0 | 207 | 22.1 | |
Day 93 | 0903 | 500 | 14.0 | 1.00 | 7.1 | 4.1 | 3.0 | 1.4 | 183.0 | 46.0 | 18.0 | 245 | 21.1 | |
Day 93 | 0904 | 500 | 15.0 | 1.10 | 7.1 | 4.2 | 2.9 | 1.4 | 84.0 | 47.0 | 17.0 | 265 | 25.9 | |
Day 93 | 0905 | 500 | 13.0 | 1.00 | 6.8 | 4.1 | 2.7 | 1.5 | 101.0 | 44.0 | 16.0 | 259 | 22.5 | |
Day 93 | 0906 | 500 | 17.0 | 1.10 | 6.7 | 4.5 | 2.2 | 2.0 | 75.0 | 65.0 | 19.0 | 261 | 23.4 | |
Day 93 | 0907 | 500 | 13.0 | 1.00 | 7.0 | 4.4 | 2.6 | 1.7 | 89.0 | 55.0 | 18.0 | 257 | 21.4 | |
Day 93 | 0908 | 500 | 17.0 | 1.10 | 7.0 | 4.0 | 3.0 | 1.3 | 87.0 | 50.0 | 19.0 | 243 | 21.7 | |
Day 93 | 0909 | 500 | 13.0 | 1.20 | 7.0 | 4.5 | 2.5 | 1.8 | 236.0 | 59.0 | 23.0 | 240 | 29.9 | |
Day 93 | 0910 | 500 | 15.0 | 0.90 | 6.6 | 4.3 | 2.3 | 1.9 | 224.0 | 65.0 | 12.0 | 244 | 44.8 | |
Day 93 | 1101 | 1000 | 12.0 | 1.20 | 7.3 | 4.9 | 2.4 | 2.0 | 91.0 | 36.0 | 18.0 | 216 | 22.6 | |
Day 93 | 1102 | 1000 | 14.0 | 0.90 | 7.0 | 4.8 | 2.2 | 2.2 | 60.0 | 34.0 | 15.0 | 222 | 21.7 | |
Day 93 | 1103 | 1000 | 13.0 | 1.10 | 7.2 | 4.7 | 2.5 | 1.9 | 120.0 | 33.0 | 17.0 | 195 | 21.2 | |
Day 93 | 1104 | 1000 | 9.0 | 1.00 | 6.9 | 4.2 | 2.7 | 1.6 | 154.0 | 37.0 | 16.0 | 183 | 21.0 | |
Day 93 | 1105 | 1000 | 14.0 | 1.00 | 6.8 | 4.7 | 2.1 | 2.2 | 138.0 | 33.0 | 7.0 | 194 | 25.7 | |
Day 93 | 1106 | 1000 | 14.0 | 1.20 | 7.2 | 4.9 | 2.3 | 2.1 | 93.0 | 31.0 | 19.0 | 222 | 27.1 | |
Day 93 | 1107 | 1000 | 14.0 | 0.90 | 6.5 | 4.3 | 2.2 | 2.0 | 116.0 | 33.0 | 10.0 | 188 | 23.2 | |
Day 93 | 1108 | 1000 | 15.0 | 1.00 | 7.1 | 4.7 | 2.4 | 2.0 | 91.0 | 34.0 | 16.0 | 198 | 29.7 | |
Day 93 | 1109 | 1000 | 14.0 | 1.10 | 7.1 | 4.9 | 2.2 | 2.2 | 84.0 | 31.0 | 18.0 | 227 | 23.0 | |
Day 93 | 1110 | 1000 | 16.0 | 1.00 | 7.4 | 4.3 | 3.1 | 1.4 | 94.0 | 30.0 | 15.0 | 228 | 22.7 | |
Abbreviations: | ||||||||||||||
NA: Not Available, U: Untreated Control, BUN: Urea Nitrogen, Creat: Creatinine, TP: Protein Total, ALB: Albumin, A/G Ratio: Albumin Globulin Ratio, Creat Kinase: Creatine Kinase, ALT: Alanine Aminotransferase, SDH: Sorbitol Dehydrogenase, ALP: Alkaline Phosphatase, TBA: Bile Acids Per G Tissue |