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Long-Term Study
Organ Weights Individual Animal
Study Information:
Chemical Name: | Turmeric, oleoresin (curcumin) |
CASRN: | ="8024-37-1" |
Study Number: | C60015 |
Study Length (Year Completed): |
(N/A) |
Exposure Route: | |
TDMS Number: | 0508401 |
Sex: | Female |
Strain and Species: | F 344/N Rats |
Organ Weights Individual Animal Data |
Measurement Time |
Animal Number |
Dose Group (PPM) |
Control Code |
Final Body Weight |
Final Body Weight (g) |
Day 220 |
496 |
0 |
|
|
|
Day 220 |
499 |
0 |
|
|
|
Day 220 |
502 |
0 |
|
|
|
Day 220 |
505 |
0 |
|
|
|
Day 220 |
508 |
0 |
|
|
|
Day 311 |
486 |
50,000 |
|
220.4 |
|
Day 359 |
490 |
50,000 |
|
192.8 |
|
Day 365 |
497 |
0 |
|
|
|
Day 365 |
500 |
0 |
|
|
|
Day 365 |
503 |
0 |
|
|
|
Day 365 |
506 |
0 |
|
|
|
Day 365 |
509 |
0 |
|
|
|
Day 367 |
447 |
50,000 |
|
226.6 |
|
Day 414 |
382 |
10,000 |
|
204 |
|
Day 444 |
323 |
2,000 |
|
202.8 |
|
Day 455 |
279 |
0 |
|
295.6 |
|
Day 455 |
282 |
0 |
|
350 |
|
Day 455 |
290 |
0 |
|
319.6 |
|
Day 455 |
291 |
0 |
|
316.6 |
|
Day 455 |
321 |
2,000 |
|
320 |
|
Day 455 |
333 |
2,000 |
|
337 |
|
Day 455 |
350 |
2,000 |
|
295.8 |
|
Day 455 |
358 |
2,000 |
|
336.4 |
|
Day 455 |
394 |
10,000 |
|
313 |
|
Day 455 |
401 |
10,000 |
|
322 |
|
Day 455 |
403 |
10,000 |
|
333 |
|
Day 455 |
407 |
10,000 |
|
288.8 |
|
Day 455 |
412 |
10,000 |
|
288.6 |
|
Day 455 |
420 |
10,000 |
|
272.2 |
|
Day 455 |
423 |
10,000 |
|
291.2 |
|
Day 455 |
426 |
10,000 |
|
305.6 |
|
Day 455 |
427 |
10,000 |
|
338.2 |
|
Day 455 |
432 |
10,000 |
|
148.8 |
|
Day 455 |
457 |
50,000 |
|
242.4 |
|
Day 455 |
471 |
50,000 |
|
300.4 |
|
Day 455 |
495 |
50,000 |
|
304.4 |
|
Day 456 |
429 |
10,000 |
|
221.4 |
|
Day 457 |
262 |
0 |
|
319 |
|
Day 457 |
263 |
0 |
|
271 |
|
Day 457 |
272 |
0 |
|
309 |
|
Day 457 |
273 |
0 |
|
309.4 |
|
Day 457 |
283 |
0 |
|
315.8 |
|
Day 457 |
287 |
0 |
|
307 |
|
Day 457 |
327 |
2,000 |
|
342.8 |
|
Day 457 |
329 |
2,000 |
|
317.6 |
|
Day 457 |
334 |
2,000 |
|
290 |
|
Day 457 |
345 |
2,000 |
|
313.6 |
|
Day 457 |
359 |
2,000 |
|
307.8 |
|
Day 457 |
363 |
2,000 |
|
315.8 |
|
Day 457 |
395 |
10,000 |
|
296.2 |
|
Day 457 |
463 |
50,000 |
|
289.6 |
|
Day 457 |
472 |
50,000 |
|
288.8 |
|
Day 457 |
480 |
50,000 |
|
259.4 |
|
Day 457 |
482 |
50,000 |
|
287 |
|
Day 457 |
484 |
50,000 |
|
257.4 |
|
Day 457 |
493 |
50,000 |
|
261.2 |
|
Day 461 |
267 |
0 |
|
273.8 |
|
Day 462 |
425 |
10,000 |
|
253.2 |
|
Day 468 |
306 |
0 |
|
211.6 |
|
Day 489 |
408 |
10,000 |
|
265.4 |
|
Day 493 |
492 |
50,000 |
|
196.3 |
|
Day 506 |
373 |
2,000 |
|
240.4 |
|
Day 510 |
453 |
50,000 |
|
230.7 |
|
Day 517 |
294 |
0 |
|
312 |
|
Day 517 |
312 |
0 |
|
291.4 |
|
Day 518 |
467 |
50,000 |
|
227.9 |
|
Day 519 |
379 |
10,000 |
|
243.2 |
|
Day 526 |
430 |
10,000 |
|
265.7 |
|
Day 528 |
424 |
10,000 |
|
236.2 |
|
Day 528 |
452 |
50,000 |
|
226.6 |
|
Day 542 |
498 |
0 |
|
|
|
Day 542 |
501 |
0 |
|
|
|
Day 542 |
504 |
0 |
|
|
|
Day 542 |
507 |
0 |
|
|
|
Day 542 |
510 |
0 |
|
|
|
Day 550 |
292 |
0 |
|
354.8 |
|
Day 552 |
349 |
2,000 |
|
258.6 |
|
Day 552 |
351 |
2,000 |
|
340.6 |
|
Day 553 |
260 |
0 |
|
240.8 |
|
Day 556 |
404 |
10,000 |
|
326.2 |
|
Day 560 |
340 |
2,000 |
|
255 |
|
Day 574 |
296 |
0 |
|
255 |
|
Day 576 |
391 |
10,000 |
|
243.2 |
|
Day 577 |
387 |
10,000 |
|
258 |
|
Day 591 |
343 |
2,000 |
|
247 |
|
Day 591 |
421 |
10,000 |
|
258.6 |
|
Day 595 |
336 |
2,000 |
|
357.8 |
|
Day 598 |
366 |
2,000 |
|
228.2 |
|
Day 598 |
460 |
50,000 |
|
241.6 |
|
Day 603 |
293 |
0 |
|
324.6 |
|
Day 615 |
346 |
2,000 |
|
252 |
|
Day 622 |
339 |
2,000 |
|
347.6 |
|
Day 624 |
442 |
50,000 |
|
246 |
|
Day 632 |
489 |
50,000 |
|
276.2 |
|
Day 643 |
281 |
0 |
|
256 |
|
Day 643 |
315 |
0 |
|
252.8 |
|
Day 643 |
398 |
10,000 |
|
193.2 |
|
Day 646 |
299 |
0 |
|
240.8 |
|
Day 647 |
362 |
2,000 |
|
263.8 |
|
Day 647 |
402 |
10,000 |
|
349 |
|
Day 654 |
330 |
2,000 |
|
275 |
|
Day 655 |
380 |
10,000 |
|
239.4 |
|
Day 659 |
483 |
50,000 |
|
294.6 |
|
Day 661 |
491 |
50,000 |
|
337.4 |
|
Day 667 |
338 |
2,000 |
|
259.5 |
|
Day 673 |
437 |
50,000 |
|
278.4 |
|
Day 673 |
475 |
50,000 |
|
220.2 |
|
Day 676 |
284 |
0 |
|
297.2 |
|
Day 677 |
377 |
10,000 |
|
287.8 |
|
Day 680 |
289 |
0 |
|
243.6 |
|
Day 680 |
390 |
10,000 |
|
282.6 |
|
Day 681 |
297 |
0 |
|
345.2 |
|
Day 685 |
372 |
2,000 |
|
248 |
|
Day 688 |
389 |
10,000 |
|
404.2 |
|
Day 692 |
305 |
0 |
|
273.4 |
|
Day 694 |
335 |
2,000 |
|
314.2 |
|
Day 700 |
320 |
2,000 |
|
259 |
|
Day 700 |
328 |
2,000 |
|
249.4 |
|
Day 700 |
353 |
2,000 |
|
278 |
|
Day 700 |
361 |
2,000 |
|
376.2 |
|
Day 700 |
368 |
2,000 |
|
233.4 |
|
Day 700 |
386 |
10,000 |
|
253.6 |
|
Day 700 |
417 |
10,000 |
|
331.8 |
|
Day 700 |
469 |
50,000 |
|
224.2 |
|
Day 702 |
347 |
2,000 |
|
332 |
|
Day 702 |
348 |
2,000 |
|
253 |
|
Day 702 |
371 |
2,000 |
|
330.8 |
|
Day 707 |
314 |
0 |
|
261.2 |
|
Day 708 |
409 |
10,000 |
|
318.2 |
|
Day 708 |
431 |
10,000 |
|
334 |
|
Day 708 |
438 |
50,000 |
|
329 |
|
Day 717 |
313 |
0 |
|
292.4 |
|
Day 721 |
476 |
50,000 |
|
240.6 |
|
Day 727 |
446 |
50,000 |
|
320.2 |
|
Day 727 |
448 |
50,000 |
|
334.8 |
|
Day 727 |
449 |
50,000 |
|
321.6 |
|
Day 727 |
450 |
50,000 |
|
332.4 |
|
Day 727 |
451 |
50,000 |
|
306 |
|
Day 727 |
455 |
50,000 |
|
320.2 |
|
Day 727 |
473 |
50,000 |
|
278 |
|
Day 727 |
474 |
50,000 |
|
308.6 |
|
Day 727 |
477 |
50,000 |
|
325.2 |
|
Day 727 |
478 |
50,000 |
|
278.8 |
|
Day 727 |
479 |
50,000 |
|
323.6 |
|
Day 727 |
481 |
50,000 |
|
310.4 |
|
Day 727 |
485 |
50,000 |
|
346.2 |
|
Day 727 |
494 |
50,000 |
|
307.6 |
|
Day 728 |
454 |
50,000 |
|
323.4 |
|
Day 728 |
466 |
50,000 |
|
296 |
|
Day 728 |
468 |
50,000 |
|
319.2 |
|
Day 728 |
470 |
50,000 |
|
303.4 |
|
Day 728 |
487 |
50,000 |
|
309.6 |
|
Day 728 |
488 |
50,000 |
|
323.2 |
|
Day 729 |
381 |
10,000 |
|
277.4 |
|
Day 729 |
383 |
10,000 |
|
308.4 |
|
Day 729 |
384 |
10,000 |
|
281.4 |
|
Day 729 |
385 |
10,000 |
|
272.6 |
|
Day 729 |
388 |
10,000 |
|
308.6 |
|
Day 729 |
392 |
10,000 |
|
316.2 |
|
Day 729 |
393 |
10,000 |
|
307.6 |
|
Day 729 |
397 |
10,000 |
|
304.2 |
|
Day 729 |
399 |
10,000 |
|
305.2 |
|
Day 729 |
433 |
10,000 |
|
338.2 |
|
Day 729 |
434 |
10,000 |
|
299.7 |
|
Day 729 |
435 |
10,000 |
|
292.8 |
|
Day 729 |
436 |
50,000 |
|
328.8 |
|
Day 729 |
439 |
50,000 |
|
334.4 |
|
Day 729 |
440 |
50,000 |
|
289.4 |
|
Day 729 |
441 |
50,000 |
|
321 |
|
Day 729 |
443 |
50,000 |
|
345.2 |
|
Day 729 |
444 |
50,000 |
|
326.4 |
|
Day 729 |
445 |
50,000 |
|
335.8 |
|
Day 729 |
456 |
50,000 |
|
311.2 |
|
Day 729 |
458 |
50,000 |
|
326.6 |
|
Day 729 |
459 |
50,000 |
|
309 |
|
Day 729 |
461 |
50,000 |
|
293.6 |
|
Day 729 |
462 |
50,000 |
|
324.6 |
|
Day 729 |
464 |
50,000 |
|
315.6 |
|
Day 729 |
465 |
50,000 |
|
356 |
|
Day 730 |
257 |
0 |
|
322.4 |
|
Day 730 |
376 |
10,000 |
|
319.4 |
|
Day 730 |
378 |
10,000 |
|
362.4 |
|
Day 730 |
396 |
10,000 |
|
302 |
|
Day 730 |
400 |
10,000 |
|
323.8 |
|
Day 730 |
406 |
10,000 |
|
310.8 |
|
Day 730 |
410 |
10,000 |
|
244.4 |
|
Day 730 |
411 |
10,000 |
|
360.2 |
|
Day 730 |
413 |
10,000 |
|
333.4 |
|
Day 730 |
414 |
10,000 |
|
340.8 |
|
Day 730 |
415 |
10,000 |
|
337 |
|
Day 730 |
418 |
10,000 |
|
344.4 |
|
Day 730 |
422 |
10,000 |
|
292 |
|
Day 730 |
428 |
10,000 |
|
299 |
|
Day 731 |
316 |
2,000 |
|
291.6 |
|
Day 731 |
317 |
2,000 |
|
336 |
|
Day 731 |
318 |
2,000 |
|
280 |
|
Day 731 |
319 |
2,000 |
|
329.8 |
|
Day 731 |
326 |
2,000 |
|
343.2 |
|
Day 731 |
331 |
2,000 |
|
326.1 |
|
Day 731 |
332 |
2,000 |
|
312 |
|
Day 731 |
344 |
2,000 |
|
321.7 |
|
Day 731 |
405 |
10,000 |
|
303 |
|
Day 731 |
416 |
10,000 |
|
389.2 |
|
Day 731 |
419 |
10,000 |
|
329 |
|
Day 732 |
322 |
2,000 |
|
338.4 |
|
Day 732 |
341 |
2,000 |
|
306.8 |
|
Day 732 |
342 |
2,000 |
|
370.2 |
|
Day 732 |
352 |
2,000 |
|
338.8 |
|
Day 732 |
354 |
2,000 |
|
356.4 |
|
Day 732 |
355 |
2,000 |
|
327.8 |
|
Day 732 |
356 |
2,000 |
|
376.8 |
|
Day 732 |
357 |
2,000 |
|
351.8 |
|
Day 732 |
360 |
2,000 |
|
334.8 |
|
Day 732 |
364 |
2,000 |
|
293 |
|
Day 732 |
374 |
2,000 |
|
280 |
|
Day 733 |
324 |
2,000 |
|
383.6 |
|
Day 733 |
325 |
2,000 |
|
322.2 |
|
Day 733 |
337 |
2,000 |
|
316.8 |
|
Day 733 |
365 |
2,000 |
|
346 |
|
Day 733 |
367 |
2,000 |
|
326.2 |
|
Day 733 |
375 |
2,000 |
|
359 |
|
Day 734 |
256 |
0 |
|
341.2 |
|
Day 734 |
258 |
0 |
|
242.6 |
|
Day 734 |
261 |
0 |
|
302.8 |
|
Day 734 |
264 |
0 |
|
354.5 |
|
Day 734 |
265 |
0 |
|
358 |
|
Day 734 |
266 |
0 |
|
320 |
|
Day 734 |
274 |
0 |
|
358.8 |
|
Day 734 |
275 |
0 |
|
344 |
|
Day 734 |
276 |
0 |
|
307.3 |
|
Day 734 |
277 |
0 |
|
308.6 |
|
Day 734 |
278 |
0 |
|
328 |
|
Day 734 |
280 |
0 |
|
283.8 |
|
Day 734 |
286 |
0 |
|
335.8 |
|
Day 734 |
288 |
0 |
|
344.6 |
|
Day 734 |
295 |
0 |
|
339.5 |
|
Day 734 |
300 |
0 |
|
339.3 |
|
Day 734 |
307 |
0 |
|
372 |
|
Day 734 |
308 |
0 |
|
347 |
|
Day 734 |
309 |
0 |
|
310.7 |
|
Day 734 |
369 |
2,000 |
|
319.4 |
|
Day 734 |
370 |
2,000 |
|
350.4 |
|
Day 735 |
259 |
0 |
|
333.6 |
|
Day 735 |
268 |
0 |
|
298.4 |
|
Day 735 |
269 |
0 |
|
356.2 |
|
Day 735 |
270 |
0 |
|
349.2 |
|
Day 735 |
271 |
0 |
|
360 |
|
Day 735 |
285 |
0 |
|
312.8 |
|
Day 735 |
298 |
0 |
|
365.6 |
|
Day 735 |
301 |
0 |
|
298.2 |
|
Day 735 |
302 |
0 |
|
329.4 |
|
Day 735 |
303 |
0 |
|
334.8 |
|
Day 735 |
304 |
0 |
|
348 |
|
Day 735 |
310 |
0 |
|
337.8 |
|
Day 735 |
311 |
0 |
|
372.6 |
|
Abbreviations: |
NA: Not Available
|