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Chemical Name: | Ginseng |
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CASRN: | ="50647-08-0" |
Study Number: | C20005 |
Study Length (Year Completed): | 13 Weeks (N/A) |
Exposure Route: | GAV |
TDMS Number: | 2000503.ss |
Sex: | Male |
Strain and Species: | Fischer 344 Rats |
Hematology Individual Animal Data | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Measurement Time | Animal Number | Dose Group (mg/kg) | Control Code | Erythrcyt (million/uL) | Hgb (g/dL) | HCT (Automated) (%) | MCV (fL) | MCH (pg) | MCHC (g/dL) | Platelet (1000/mL) | Leukocytes (1000/mL) | Neut (1000/mL) | Lymph (1000/mL) | Mono (1000/mL) | EOS (1000/mL) | Basophils (1000/mL) |
Day 92 | 0001 | 0 | V | 9.10 | 15.7 | 49.3 | 54.2 | 17.2 | 31.8 | 705 | 10.44 | 1.10 | 8.93 | 0.30 | 0.07 | 0.03 |
Day 92 | 0002 | 0 | V | 8.70 | 15.0 | 46.6 | 53.6 | 17.3 | 32.3 | 723 | 10.76 | 1.21 | 9.21 | 0.25 | 0.05 | 0.04 |
Day 92 | 0003 | 0 | V | 8.88 | 15.2 | 47.4 | 53.4 | 17.1 | 32.0 | 716 | 11.09 | 1.16 | 9.64 | 0.19 | 0.06 | 0.04 |
Day 92 | 0004 | 0 | V | 9.30 | 15.6 | 48.9 | 52.6 | 16.8 | 31.9 | 596 | 10.90 | 1.43 | 8.93 | 0.41 | 0.09 | 0.05 |
Day 92 | 0005 | 0 | V | 8.78 | 15.1 | 46.3 | 52.7 | 17.2 | 32.6 | 765 | 11.29 | 1.03 | 9.76 | 0.37 | 0.09 | 0.03 |
Day 92 | 0006 | 0 | V | 8.94 | 15.4 | 48.6 | 54.4 | 17.3 | 31.7 | 732 | 10.52 | 1.33 | 8.82 | 0.25 | 0.07 | 0.05 |
Day 92 | 0007 | 0 | V | 8.67 | 14.3 | 44.9 | 51.8 | 16.5 | 31.8 | 586 | 8.31 | 0.87 | 7.16 | 0.20 | 0.04 | 0.05 |
Day 92 | 0008 | 0 | V | 8.97 | 15.5 | 48.7 | 54.3 | 17.3 | 31.8 | 630 | 11.76 | 1.41 | 9.87 | 0.24 | 0.20 | 0.03 |
Day 92 | 0009 | 0 | V | 9.20 | 15.4 | 48.4 | 52.6 | 16.8 | 31.9 | 672 | 11.76 | 1.24 | 10.13 | 0.29 | 0.06 | 0.05 |
Day 92 | 0010 | 0 | V | 9.27 | 16.0 | 49.5 | 53.4 | 17.3 | 32.3 | 675 | 10.72 | 1.24 | 9.09 | 0.30 | 0.06 | 0.04 |
Day 92 | 0011 | 1000 | 9.06 | 15.7 | 48.8 | 53.8 | 17.3 | 32.1 | 742 | 11.16 | 1.52 | 9.26 | 0.22 | 0.11 | 0.07 | |
Day 92 | 0012 | 1000 | 9.52 | 15.8 | 50.2 | 52.7 | 16.6 | 31.5 | 618 | 11.12 | 1.34 | 9.28 | 0.31 | 0.08 | 0.10 | |
Day 92 | 0013 | 1000 | 8.50 | 15.6 | 47.7 | 56.1 | 18.4 | 32.8 | 697 | 9.89 | 1.39 | 8.19 | 0.20 | 0.08 | 0.03 | |
Day 92 | 0014 | 1000 | 8.64 | 14.8 | 46.0 | 53.2 | 17.1 | 32.1 | 681 | 10.62 | 1.12 | 9.20 | 0.19 | 0.08 | 0.04 | |
Day 92 | 0015 | 1000 | 8.91 | 15.3 | 48.6 | 54.6 | 17.2 | 31.5 | 781 | 11.56 | 1.31 | 9.92 | 0.21 | 0.07 | 0.04 | |
Day 92 | 0016 | 1000 | 9.11 | 15.6 | 47.8 | 52.4 | 17.1 | 32.7 | 632 | 10.75 | 1.36 | 8.83 | 0.28 | 0.25 | 0.03 | |
Day 92 | 0017 | 1000 | 8.67 | 14.8 | 46.3 | 53.4 | 17.1 | 32.0 | 728 | 11.95 | 1.37 | 10.29 | 0.17 | 0.07 | 0.06 | |
Day 92 | 0018 | 1000 | 9.10 | 15.1 | 48.5 | 53.2 | 16.6 | 31.1 | 734 | 9.94 | 1.26 | 8.31 | 0.26 | 0.08 | 0.02 | |
Day 92 | 0019 | 1000 | 9.07 | 15.6 | 46.7 | 51.4 | 17.2 | 33.4 | 718 | 8.89 | 1.24 | 7.22 | 0.25 | 0.15 | 0.02 | |
Day 92 | 0020 | 1000 | 8.56 | 14.5 | 45.3 | 52.9 | 16.9 | 31.9 | 658 | 9.78 | 1.23 | 8.29 | 0.13 | 0.10 | 0.03 | |
Day 92 | 0021 | 2000 | 8.86 | 14.8 | 46.6 | 52.7 | 16.7 | 31.8 | 736 | 10.70 | 1.16 | 9.27 | 0.14 | 0.07 | 0.07 | |
Day 92 | 0022 | 2000 | 8.90 | 15.3 | 47.9 | 53.8 | 17.2 | 32.0 | 753 | 9.85 | 1.17 | 8.44 | 0.12 | 0.08 | 0.04 | |
Day 92 | 0023 | 2000 | 8.77 | 15.2 | 47.1 | 53.7 | 17.3 | 32.3 | 808 | 10.98 | 1.36 | 9.27 | 0.23 | 0.07 | 0.05 | |
Day 92 | 0024 | 2000 | 8.54 | 14.8 | 45.1 | 52.8 | 17.3 | 32.7 | 749 | 10.74 | 1.26 | 9.18 | 0.15 | 0.10 | 0.05 | |
Day 92 | 0025 | 2000 | 8.76 | 15.2 | 47.2 | 53.9 | 17.4 | 32.2 | 690 | 11.97 | 1.38 | 10.26 | 0.21 | 0.05 | 0.06 | |
Day 92 | 0026 | 2000 | 8.71 | 15.1 | 45.5 | 52.3 | 17.4 | 33.2 | 614 | 12.74 | 1.44 | 10.90 | 0.25 | 0.11 | 0.05 | |
Day 92 | 0027 | 2000 | 8.78 | 14.8 | 46.5 | 53.0 | 16.9 | 31.9 | 771 | 11.34 | 1.45 | 9.46 | 0.27 | 0.09 | 0.07 | |
Day 92 | 0028 | 2000 | 8.97 | 14.9 | 48.4 | 54.0 | 16.6 | 30.8 | 723 | 10.12 | 1.07 | 8.79 | 0.16 | 0.05 | 0.04 | |
Day 92 | 0029 | 2000 | 8.80 | 15.2 | 46.4 | 52.7 | 17.2 | 32.7 | 604 | 11.09 | 1.42 | 9.30 | 0.20 | 0.11 | 0.05 | |
Day 92 | 0030 | 2000 | 8.80 | 15.2 | 46.9 | 53.3 | 17.2 | 32.3 | 703 | 11.25 | 1.32 | 9.55 | 0.24 | 0.09 | 0.06 | |
Day 92 | 0031 | 3000 | 8.74 | 15.0 | 47.1 | 53.8 | 17.1 | 31.8 | 753 | 12.37 | 1.63 | 10.37 | 0.25 | 0.07 | 0.05 | |
Day 92 | 0032 | 3000 | 9.16 | 15.5 | 49.3 | 53.9 | 16.9 | 31.5 | 740 | 11.71 | 1.30 | 10.06 | 0.22 | 0.08 | 0.05 | |
Day 92 | 0033 | 3000 | 8.67 | 14.8 | 46.2 | 53.3 | 17.1 | 32.1 | 759 | 11.21 | 1.06 | 9.83 | 0.24 | 0.06 | 0.03 | |
Day 92 | 0034 | 3000 | 9.54 | 15.9 | 50.0 | 52.4 | 16.7 | 31.8 | 572 | 12.18 | 1.84 | 9.70 | 0.32 | 0.26 | 0.07 | |
Day 92 | 0035 | 3000 | 8.75 | 14.8 | 47.1 | 53.9 | 16.9 | 31.4 | 730 | 11.28 | 1.25 | 9.77 | 0.15 | 0.08 | 0.03 | |
Day 92 | 0036 | 3000 | 8.41 | 14.4 | 44.6 | 53.0 | 17.2 | 32.4 | 729 | 11.13 | 1.23 | 9.61 | 0.16 | 0.05 | 0.07 | |
Day 92 | 0037 | 3000 | 8.88 | 15.1 | 48.3 | 54.4 | 17.0 | 31.3 | 641 | 11.60 | 1.16 | 10.15 | 0.19 | 0.06 | 0.05 | |
Day 92 | 0038 | 3000 | 9.08 | 15.5 | 47.8 | 52.6 | 17.0 | 32.3 | 700 | 11.72 | 1.53 | 9.76 | 0.30 | 0.09 | 0.04 | |
Day 92 | 0039 | 3000 | 9.07 | 14.9 | 48.2 | 53.1 | 16.5 | 31.0 | 708 | 9.98 | 1.02 | 8.72 | 0.17 | 0.06 | 0.03 | |
Day 92 | 0040 | 3000 | 9.16 | 15.7 | 49.6 | 54.2 | 17.1 | 31.6 | 699 | 12.17 | 1.71 | 10.09 | 0.22 | 0.09 | 0.05 | |
Day 92 | 0041 | 4000 | 9.37 | 15.5 | 49.2 | 52.5 | 16.5 | 31.4 | 759 | 12.69 | 1.49 | 10.80 | 0.21 | 0.13 | 0.05 | |
Day 92 | 0042 | 4000 | 9.19 | 15.5 | 48.8 | 53.1 | 16.8 | 31.7 | 765 | 12.84 | 1.62 | 10.81 | 0.19 | 0.12 | 0.11 | |
Day 92 | 0043 | 4000 | 8.99 | 15.5 | 47.7 | 53.0 | 17.2 | 32.5 | 695 | 10.91 | 1.47 | 9.00 | 0.28 | 0.08 | 0.09 | |
Day 92 | 0044 | 4000 | 8.77 | 15.1 | 47.0 | 53.5 | 17.2 | 32.1 | 709 | 11.12 | 1.40 | 9.36 | 0.24 | 0.04 | 0.07 | |
Day 92 | 0045 | 4000 | 9.60 | 16.0 | 51.0 | 53.2 | 16.7 | 31.4 | 719 | 12.14 | 1.62 | 10.23 | 0.18 | 0.07 | 0.04 | |
Day 92 | 0047 | 4000 | 9.21 | 15.2 | 49.0 | 53.3 | 16.5 | 31.0 | 704 | 11.27 | 1.56 | 9.31 | 0.28 | 0.07 | 0.05 | |
Day 92 | 0048 | 4000 | 9.15 | 15.5 | 48.6 | 53.1 | 16.9 | 31.8 | 753 | 10.53 | 1.13 | 9.03 | 0.25 | 0.07 | 0.04 | |
Day 92 | 0049 | 4000 | 9.28 | 15.7 | 48.7 | 52.5 | 16.9 | 32.2 | 633 | 12.81 | 1.85 | 10.57 | 0.23 | 0.09 | 0.06 | |
Day 92 | 0050 | 4000 | 9.51 | 15.7 | 50.9 | 53.5 | 16.5 | 30.9 | 755 | 10.91 | 1.33 | 9.25 | 0.24 | 0.05 | 0.03 | |
Day 92 | 0051 | 5000 | 8.93 | 15.2 | 47.2 | 52.9 | 17.0 | 32.1 | 649 | 10.96 | 1.69 | 8.87 | 0.20 | 0.16 | 0.04 | |
Day 92 | 0052 | 5000 | 7.74 | 14.0 | 42.8 | 55.3 | 18.0 | 32.6 | 835 | 11.23 | 1.27 | 9.69 | 0.17 | 0.04 | 0.07 | |
Day 92 | 0053 | 5000 | 9.47 | 15.7 | 49.4 | 52.2 | 16.6 | 31.8 | 670 | 11.95 | 1.54 | 9.93 | 0.33 | 0.10 | 0.05 | |
Day 92 | 0054 | 5000 | 9.43 | 15.8 | 50.6 | 53.6 | 16.7 | 31.2 | 730 | 10.90 | 1.54 | 9.04 | 0.22 | 0.08 | 0.04 | |
Day 92 | 0055 | 5000 | 9.37 | 15.8 | 49.9 | 53.2 | 16.9 | 31.7 | 726 | 13.50 | 1.60 | 11.49 | 0.23 | 0.08 | 0.11 | |
Day 92 | 0056 | 5000 | 9.26 | 15.8 | 47.7 | 51.5 | 17.1 | 33.1 | 681 | 10.78 | 1.29 | 9.01 | 0.33 | 0.09 | 0.06 | |
Day 92 | 0057 | 5000 | 9.30 | 15.4 | 49.1 | 52.8 | 16.6 | 31.4 | 752 | 12.31 | 1.40 | 10.52 | 0.27 | 0.07 | 0.05 | |
Day 92 | 0058 | 5000 | 9.72 | 16.0 | 51.4 | 52.9 | 16.4 | 31.0 | 744 | 12.61 | 1.69 | 10.55 | 0.20 | 0.08 | 0.08 | |
Day 92 | 0059 | 5000 | 9.35 | 15.7 | 50.2 | 53.7 | 16.8 | 31.2 | 634 | 10.34 | 1.36 | 8.69 | 0.19 | 0.06 | 0.04 | |
Day 92 | 0060 | 5000 | 9.27 | 15.6 | 49.7 | 53.7 | 16.8 | 31.4 | 714 | 10.60 | 1.36 | 8.96 | 0.17 | 0.05 | 0.05 | |
Abbreviations: | ||||||||||||||||
NA: Not Available, V: Vehicle Control, Erythrcyt: Red Blood Cell Count, Hgb: Hemoglobin, HCT (Automated): Hematocrit, MCV: Mean Corpuscular Volume, MCH: Mean Cell Hemoglobin, MCHC: Mean Cell Hemoglobin Concentration, Platelet: Platelet Count, Leukocytes: White Blood Cell Count, Neut: Neutrophil Count, Lymph: Lymphocyte Count, Mono: Monocyte Count, EOS: Eosinophil Count, Basophils: Basophil Count |