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Long-Term Study
Organ Weights Individual Animal
Study Information:
Chemical Name: | Hexachlorocyclopentadiene |
CASRN: | ="77-47-4" |
Study Number: | C55607B |
Study Length (Year Completed): |
(N/A) |
Exposure Route: | RESPIRATORY EXPOSURE WHOLE BODY |
TDMS Number: | 0511401 |
Sex: | Female |
Strain and Species: | F 344/N Rats |
Organ Weights Individual Animal Data |
Measurement Time |
Animal Number |
Dose Group (PPM) |
Control Code |
Final Body Weight (g) |
Day 37 |
540 |
0.05 |
|
248.2 |
Day 366 |
557 |
0.05 |
|
217.5 |
Day 367 |
503 |
0.05 |
|
165.5 |
Day 376 |
138 |
0 |
|
186 |
Day 376 |
158 |
0 |
|
140.2 |
Day 402 |
536 |
0.05 |
|
149 |
Day 459 |
109 |
0 |
|
324.7 |
Day 459 |
110 |
0 |
|
287.4 |
Day 459 |
116 |
0 |
|
345.1 |
Day 459 |
118 |
0 |
|
337.1 |
Day 459 |
120 |
0 |
|
275.4 |
Day 459 |
122 |
0 |
|
248.4 |
Day 459 |
125 |
0 |
|
295.1 |
Day 459 |
144 |
0 |
|
321.7 |
Day 459 |
146 |
0 |
|
331.6 |
Day 459 |
151 |
0 |
|
334.2 |
Day 459 |
301 |
0.01 |
|
309.8 |
Day 459 |
304 |
0.01 |
|
346.3 |
Day 459 |
312 |
0.01 |
|
335.3 |
Day 459 |
314 |
0.01 |
|
322.7 |
Day 459 |
315 |
0.01 |
|
315.4 |
Day 459 |
317 |
0.01 |
|
284 |
Day 459 |
329 |
0.01 |
|
386.1 |
Day 459 |
338 |
0.01 |
|
325.6 |
Day 459 |
345 |
0.01 |
|
324.4 |
Day 459 |
359 |
0.01 |
|
291.1 |
Day 459 |
501 |
0.05 |
|
354.9 |
Day 459 |
504 |
0.05 |
|
357.7 |
Day 459 |
506 |
0.05 |
|
330.1 |
Day 459 |
521 |
0.05 |
|
313.2 |
Day 459 |
524 |
0.05 |
|
285.3 |
Day 459 |
532 |
0.05 |
|
317.8 |
Day 459 |
544 |
0.05 |
|
334.9 |
Day 459 |
547 |
0.05 |
|
308.1 |
Day 459 |
549 |
0.05 |
|
292.4 |
Day 459 |
556 |
0.05 |
|
344.1 |
Day 459 |
718 |
0.2 |
|
309.5 |
Day 459 |
720 |
0.2 |
|
315.3 |
Day 459 |
727 |
0.2 |
|
330.4 |
Day 459 |
732 |
0.2 |
|
300.9 |
Day 459 |
733 |
0.2 |
|
304.8 |
Day 459 |
735 |
0.2 |
|
306.4 |
Day 459 |
739 |
0.2 |
|
277.7 |
Day 459 |
742 |
0.2 |
|
345 |
Day 459 |
751 |
0.2 |
|
313.6 |
Day 459 |
760 |
0.2 |
|
314.8 |
Day 488 |
126 |
0 |
|
402.3 |
Day 502 |
121 |
0 |
|
354.2 |
Day 521 |
309 |
0.01 |
|
337.3 |
Day 528 |
748 |
0.2 |
|
323.7 |
Day 541 |
741 |
0.2 |
|
219.2 |
Day 549 |
551 |
0.05 |
|
229.7 |
Day 550 |
509 |
0.05 |
|
299.3 |
Day 561 |
559 |
0.05 |
|
212.2 |
Day 562 |
543 |
0.05 |
|
241.5 |
Day 565 |
341 |
0.01 |
|
306.2 |
Day 569 |
511 |
0.05 |
|
208 |
Day 569 |
728 |
0.2 |
|
307.3 |
Day 585 |
530 |
0.05 |
|
272.1 |
Day 588 |
756 |
0.2 |
|
242.7 |
Day 590 |
522 |
0.05 |
|
310.7 |
Day 597 |
539 |
0.05 |
|
271.8 |
Day 597 |
759 |
0.2 |
|
311.5 |
Day 611 |
508 |
0.05 |
|
273.8 |
Day 617 |
725 |
0.2 |
|
255.7 |
Day 618 |
558 |
0.05 |
|
325.3 |
Day 621 |
348 |
0.01 |
|
269.4 |
Day 625 |
124 |
0 |
|
252.4 |
Day 625 |
356 |
0.01 |
|
242 |
Day 625 |
712 |
0.2 |
|
252.3 |
Day 626 |
730 |
0.2 |
|
242.6 |
Day 628 |
754 |
0.2 |
|
367.4 |
Day 635 |
722 |
0.2 |
|
263.8 |
Day 638 |
332 |
0.01 |
|
226.1 |
Day 639 |
132 |
0 |
|
237.2 |
Day 639 |
137 |
0 |
|
243.8 |
Day 640 |
155 |
0 |
|
323.6 |
Day 642 |
516 |
0.05 |
|
283.5 |
Day 652 |
502 |
0.05 |
|
260.2 |
Day 653 |
107 |
0 |
|
259.2 |
Day 654 |
324 |
0.01 |
|
272.5 |
Day 654 |
327 |
0.01 |
|
282.4 |
Day 658 |
723 |
0.2 |
|
286.7 |
Day 659 |
323 |
0.01 |
|
275.1 |
Day 660 |
119 |
0 |
|
312.6 |
Day 663 |
160 |
0 |
|
247 |
Day 667 |
740 |
0.2 |
|
258.9 |
Day 667 |
746 |
0.2 |
|
283.3 |
Day 668 |
326 |
0.01 |
|
287.3 |
Day 668 |
716 |
0.2 |
|
295.1 |
Day 677 |
123 |
0 |
|
253.3 |
Day 680 |
106 |
0 |
|
353.3 |
Day 681 |
102 |
0 |
|
291.3 |
Day 681 |
140 |
0 |
|
275.8 |
Day 681 |
322 |
0.01 |
|
271.4 |
Day 683 |
141 |
0 |
|
241.7 |
Day 683 |
311 |
0.01 |
|
246.3 |
Day 686 |
134 |
0 |
|
278.5 |
Day 691 |
353 |
0.01 |
|
214.4 |
Day 694 |
303 |
0.01 |
|
221 |
Day 695 |
526 |
0.05 |
|
231.8 |
Day 695 |
534 |
0.05 |
|
278.2 |
Day 696 |
734 |
0.2 |
|
283.5 |
Day 703 |
112 |
0 |
|
258.2 |
Day 705 |
133 |
0 |
|
229.4 |
Day 705 |
328 |
0.01 |
|
228.5 |
Day 709 |
145 |
0 |
|
329.2 |
Day 709 |
339 |
0.01 |
|
291.8 |
Day 709 |
513 |
0.05 |
|
386.4 |
Day 710 |
719 |
0.2 |
|
325.5 |
Day 710 |
736 |
0.2 |
|
222.5 |
Day 718 |
523 |
0.05 |
|
318.3 |
Day 719 |
156 |
0 |
|
251.2 |
Day 724 |
355 |
0.01 |
|
267.4 |
Day 724 |
357 |
0.01 |
|
239.9 |
Day 724 |
721 |
0.2 |
|
273.9 |
Day 726 |
115 |
0 |
|
220.1 |
Day 726 |
724 |
0.2 |
|
268 |
Day 726 |
745 |
0.2 |
|
278.5 |
Day 730 |
701 |
0.2 |
|
310.3 |
Day 730 |
702 |
0.2 |
|
323.4 |
Day 730 |
703 |
0.2 |
|
371.6 |
Day 730 |
704 |
0.2 |
|
350.6 |
Day 730 |
705 |
0.2 |
|
293.7 |
Day 730 |
706 |
0.2 |
|
343.4 |
Day 730 |
707 |
0.2 |
|
354.5 |
Day 730 |
708 |
0.2 |
|
353.7 |
Day 730 |
709 |
0.2 |
|
339.4 |
Day 730 |
710 |
0.2 |
|
296.9 |
Day 730 |
711 |
0.2 |
|
369.9 |
Day 730 |
713 |
0.2 |
|
339.5 |
Day 730 |
714 |
0.2 |
|
371.1 |
Day 730 |
715 |
0.2 |
|
330 |
Day 730 |
717 |
0.2 |
|
334.5 |
Day 730 |
726 |
0.2 |
|
400.9 |
Day 730 |
729 |
0.2 |
|
341.2 |
Day 730 |
731 |
0.2 |
|
332.1 |
Day 730 |
737 |
0.2 |
|
305.3 |
Day 730 |
738 |
0.2 |
|
378.7 |
Day 730 |
743 |
0.2 |
|
340.2 |
Day 730 |
744 |
0.2 |
|
362.2 |
Day 730 |
747 |
0.2 |
|
383 |
Day 730 |
749 |
0.2 |
|
304.5 |
Day 730 |
750 |
0.2 |
|
401.1 |
Day 730 |
752 |
0.2 |
|
347.1 |
Day 730 |
753 |
0.2 |
|
302.6 |
Day 730 |
755 |
0.2 |
|
359.6 |
Day 730 |
757 |
0.2 |
|
352.4 |
Day 730 |
758 |
0.2 |
|
306.5 |
Day 731 |
505 |
0.05 |
|
384.8 |
Day 731 |
507 |
0.05 |
|
335 |
Day 731 |
510 |
0.05 |
|
322.6 |
Day 731 |
512 |
0.05 |
|
370.4 |
Day 731 |
514 |
0.05 |
|
386.7 |
Day 731 |
515 |
0.05 |
|
358.7 |
Day 731 |
517 |
0.05 |
|
347.5 |
Day 731 |
518 |
0.05 |
|
350.6 |
Day 731 |
519 |
0.05 |
|
344.9 |
Day 731 |
520 |
0.05 |
|
318.7 |
Day 731 |
525 |
0.05 |
|
305.4 |
Day 731 |
527 |
0.05 |
|
333.5 |
Day 731 |
528 |
0.05 |
|
344.1 |
Day 731 |
529 |
0.05 |
|
378 |
Day 731 |
531 |
0.05 |
|
374.3 |
Day 731 |
533 |
0.05 |
|
356.3 |
Day 731 |
535 |
0.05 |
|
323.7 |
Day 731 |
537 |
0.05 |
|
340 |
Day 731 |
538 |
0.05 |
|
319.9 |
Day 731 |
541 |
0.05 |
|
288.4 |
Day 731 |
542 |
0.05 |
|
371.6 |
Day 731 |
545 |
0.05 |
|
353.3 |
Day 731 |
546 |
0.05 |
|
335.8 |
Day 731 |
548 |
0.05 |
|
340.5 |
Day 731 |
550 |
0.05 |
|
366.2 |
Day 731 |
552 |
0.05 |
|
324 |
Day 731 |
553 |
0.05 |
|
337.6 |
Day 731 |
554 |
0.05 |
|
333.7 |
Day 731 |
555 |
0.05 |
|
420.1 |
Day 731 |
560 |
0.05 |
|
371.8 |
Day 732 |
302 |
0.01 |
|
385.3 |
Day 732 |
305 |
0.01 |
|
340.7 |
Day 732 |
306 |
0.01 |
|
321.5 |
Day 732 |
307 |
0.01 |
|
420.4 |
Day 732 |
308 |
0.01 |
|
369.7 |
Day 732 |
310 |
0.01 |
|
294.4 |
Day 732 |
313 |
0.01 |
|
349.8 |
Day 732 |
316 |
0.01 |
|
342 |
Day 732 |
318 |
0.01 |
|
372.1 |
Day 732 |
319 |
0.01 |
|
417.8 |
Day 732 |
320 |
0.01 |
|
338.5 |
Day 732 |
321 |
0.01 |
|
342.9 |
Day 732 |
325 |
0.01 |
|
342.3 |
Day 732 |
330 |
0.01 |
|
301.8 |
Day 732 |
331 |
0.01 |
|
333.7 |
Day 732 |
333 |
0.01 |
|
270.1 |
Day 732 |
334 |
0.01 |
|
272.4 |
Day 732 |
335 |
0.01 |
|
360.4 |
Day 732 |
336 |
0.01 |
|
311.7 |
Day 732 |
337 |
0.01 |
|
308.5 |
Day 732 |
340 |
0.01 |
|
362.2 |
Day 732 |
342 |
0.01 |
|
363 |
Day 732 |
343 |
0.01 |
|
375.7 |
Day 732 |
344 |
0.01 |
|
317 |
Day 732 |
346 |
0.01 |
|
280.1 |
Day 732 |
347 |
0.01 |
|
240.4 |
Day 732 |
349 |
0.01 |
|
302.1 |
Day 732 |
350 |
0.01 |
|
366.9 |
Day 732 |
351 |
0.01 |
|
372.1 |
Day 732 |
352 |
0.01 |
|
380.9 |
Day 732 |
354 |
0.01 |
|
356.3 |
Day 732 |
358 |
0.01 |
|
230.7 |
Day 732 |
360 |
0.01 |
|
393.5 |
Day 733 |
101 |
0 |
|
335.3 |
Day 733 |
103 |
0 |
|
329.9 |
Day 733 |
104 |
0 |
|
350.6 |
Day 733 |
105 |
0 |
|
346.6 |
Day 733 |
108 |
0 |
|
315.9 |
Day 733 |
111 |
0 |
|
334.4 |
Day 733 |
113 |
0 |
|
350.8 |
Day 733 |
114 |
0 |
|
307.1 |
Day 733 |
117 |
0 |
|
355.1 |
Day 733 |
127 |
0 |
|
324.3 |
Day 733 |
128 |
0 |
|
359.6 |
Day 733 |
129 |
0 |
|
396.8 |
Day 733 |
130 |
0 |
|
299.3 |
Day 733 |
131 |
0 |
|
285 |
Day 733 |
135 |
0 |
|
359.7 |
Day 733 |
136 |
0 |
|
284 |
Day 733 |
139 |
0 |
|
306.8 |
Day 733 |
142 |
0 |
|
363.8 |
Day 733 |
143 |
0 |
|
340.5 |
Day 733 |
147 |
0 |
|
349.9 |
Day 733 |
148 |
0 |
|
356.5 |
Day 733 |
149 |
0 |
|
321.5 |
Day 733 |
150 |
0 |
|
343.5 |
Day 733 |
152 |
0 |
|
345.3 |
Day 733 |
153 |
0 |
|
334.9 |
Day 733 |
154 |
0 |
|
370.9 |
Day 733 |
157 |
0 |
|
345.9 |
Day 733 |
159 |
0 |
|
316.1 |
Abbreviations: |
NA: Not Available
|