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Long-Term Individual Animal Neoplastic Diagnosis
Study Information:
Chemical Name: | IPD (3,3'-iminobis-1-propanol dimethanesulfonate (ester) hydrochloride) |
CASRN: | ="3458-22-8" |
Study Number: | C01547 |
Exposure Route: | Intraperitoneal Injection |
TDMS Number: | |
Sex: | Male |
Strain and Species: | Sprague Dawley Rats |
Male Individual Animal Neoplastic Diagnoses
System |
Organ |
Site |
Treatment Group |
Number Examined |
Cage Number |
Animal Number |
Weeks on Study |
Lesion Found |
Lesion Name |
Lesion Qualifier |
Removal Reason |
Alimentary System |
Intestine Large |
Cecum, Colon |
002.5 ML/KG |
28 |
NA |
2_022 |
77.00 |
1 |
Mucinous Adenocarcinoma |
|
Moribund Sacrifice |
Alimentary System |
Intestine Large |
Colon |
002.5 ML/KG |
28 |
NA |
2_044 |
77.00 |
1 |
Adenocarcinoma, Nos |
|
Natural Death |
All Others |
Unspecified |
|
Vehicle Control |
NA |
NA |
6_012 |
88.00 |
1 |
Fibrosarcoma |
|
Moribund Sacrifice |
Endocrine System |
Pituitary gland |
|
Untreated Control |
10 |
NA |
4_012 |
94.00 |
1 |
Chromophobe Carcinoma |
|
Scheduled Sacrifice |
Endocrine System |
Pituitary gland |
|
Vehicle Control |
10 |
NA |
3_023 |
94.00 |
1 |
Chromophobe Carcinoma |
|
Scheduled Sacrifice |
General Body System |
Peritoneum |
|
002.5 ML/KG |
NA |
NA |
2_064 |
77.00 |
1 |
Fibroma |
|
Moribund Sacrifice |
General Body System |
Peritoneum |
|
002.5 ML/KG |
NA |
NA |
2_064 |
77.00 |
1 |
Fibrosarcoma |
|
Moribund Sacrifice |
General Body System |
Peritoneum |
|
002.5 ML/KG |
NA |
NA |
5_011 |
63.00 |
1 |
Sarcoma, Nos |
|
Moribund Sacrifice |
General Body System |
Peritoneum |
|
002.5 ML/KG |
NA |
NA |
5_035 |
63.00 |
1 |
Sarcoma, Nos |
|
Moribund Sacrifice |
Genital System |
Testis |
|
Untreated Control |
10 |
NA |
7_024 |
88.00 |
1 |
Interstitial-Cell Tumor |
|
Scheduled Sacrifice |
Integumentary System |
Mammary gland |
|
Vehicle Control |
1 |
NA |
6_023 |
88.00 |
1 |
Adenocarcinoma, Nos |
|
Scheduled Sacrifice |
Integumentary System |
Mammary gland |
|
Vehicle Control |
1 |
NA |
6_024 |
88.00 |
1 |
Fibroadenoma |
|
Scheduled Sacrifice |
Integumentary System |
Skin |
|
Vehicle Control |
8 |
NA |
3_022 |
94.00 |
1 |
Keratoacanthoma |
|
Scheduled Sacrifice |
Nervous System |
Brain |
|
002.5 ML/KG |
22 |
NA |
1_061 |
28.00 |
1 |
Astrocytoma |
|
Natural Death |
Nervous System |
Brain |
|
002.5 ML/KG |
29 |
NA |
5_073 |
63.00 |
1 |
Astrocytoma |
|
Natural Death |
Special Senses System |
Ear |
Canal |
Untreated Control |
1 |
NA |
7_024 |
88.00 |
1 |
Squamous Cell Carcinoma |
|
Scheduled Sacrifice |
Special Senses System |
Ear |
Canal |
002.5 ML/KG |
35 |
NA |
2_031 |
77.00 |
1 |
Keratoacanthoma |
|
Moribund Sacrifice |